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1. 糖尿病性網膜症：予防および治療 diabetic retinopathy prevention and treatment
2. 糖尿病性網膜症：分類および臨床的特徴 diabetic retinopathy classification and clinical features
3. 糖尿病性網膜症：病因 diabetic retinopathy pathogenesis
4. 糖尿病性網膜症：スクリーニング diabetic retinopathy screening
5. 鎌状赤血球症の臨床症状の概要 overview of the clinical manifestations of sickle cell disease

Activation of ERK pathway is required for 15-HETE-induced angiogenesis in human umbilical vascular endothelial cells.

Wang S1, Cao W1, Xing H1, Chen YL2, Li Q1, Shen T1, Jiang C1,3, Zhu D1,2.
Journal of receptor and signal transduction research.J Recept Signal Transduct Res.2016 Jun;36(3):225-32. doi: 10.3109/10799893.2015.1077865. Epub 2015 Oct 13.
Angiogenesis plays a critical role in the progression of cardiovascular disease, retinal ischemia, or tumorigenesis. The imbalance of endothelial cell proliferation and apoptosis disturbs the establishment of the vasculogenesis, which is affected by several arachidonic acid metabolites. 15-Hydroxyei
PMID 26460784

Angiographic evidence of proliferative retinopathy predicts neuropsychiatric morbidity in diabetic patients.

Serlin Y1, Shafat T2, Levy J3, Winter A4, Shneck M3, Knyazer B3, Parmet Y5, Shalev H6, Ur E7, Friedman A8.
Psychoneuroendocrinology.Psychoneuroendocrinology.2016 May;67:163-70. doi: 10.1016/j.psyneuen.2016.02.009. Epub 2016 Feb 12.
INTRODUCTION: Diabetic retinopathy (DR) is a common vasculopathy categorized as either non-proliferative (NPDR) or proliferative (PDR),characterized by dysfunctional blood-retinal barrier (BRB) and diagnosed using fluorescein angiography (FA). Since the BRB is similar in structure and function to th
PMID 26907995

Serum fetuin-A levels are independently correlated with vascular endothelial growth factor and C-reactive protein concentrations in type 2 diabetic patients with diabetic retinopathy.

Zhou ZW1, Ju HX2, Sun MZ1, Fu QP1, Chen HM1, Ji HB1, Ji F3, Jiang DM4.
Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2016 Apr 1;455:113-7. doi: 10.1016/j.cca.2016.02.003. Epub 2016 Feb 4.
BACKGROUND: The higher expression of vascular endothelial growth factor (VEGF) and C-reactive protein (CRP) is associated with the development of diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM). Fetuin-A is shown to have proangiogenic and proinflammatory effects.METHODS: This study incl
PMID 26851648

増澤浩一/堀貞夫
東京女子医科大学雑誌 82(E1), E71-E77, 2012-01-31
極めて強力で持続的な血管収縮作用を示すペプチドであるエンドセリンは、その発見から約20年が経過し、この間に各分野での研究が進んだ。糖尿病においてはその発現亢進が網膜症初期における血流減少の原因とされ、さらには増殖網膜症への悪化要因となり得る可能性が示唆されている。また現在、vascular endothelial growth factor (VEGF)やintercellular adhesio …
NAID 110008767955

木戸口裕
東京女子医科大学雑誌 82(E1), E52-E58, 2012-01-31
本論文は眼科MOOK46 糖尿病と眼科診療(pp 170-179、1991)を短縮したものであり、内容は当時の医療水準に基づいている。,多数例の糖尿病妊婦の網膜症の経過について検討し、経過観察・治療の方針について考案した。,妊娠時に、福田分類AII(重症単純網膜症)以上の網膜症を有する例では、妊娠中に網膜症が悪化する危険性が高い。AIIの症例では、慎重な経過観察と適切な時期の光凝固により、ほとんど …
NAID 110008767952