WordNet

the main protein of the keratohyalin granules; "the specific target of the immune response in rheumatoid arthritis is filaggrin"

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Kaae J, Thyssen JP, Johansen JD, Meldgaard M, Linneberg A, Allen M, Skov L.SourceDepartment of Dermato-Allergology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.
The British journal of dermatology.Br J Dermatol.2013 Aug 8. doi: 10.1111/bjd.12573. [Epub ahead of print]
Basal cell carcinoma (BCC) is prevalent in lightly-pigmented Europeans. While ultraviolet (UV) radiation is an important risk factor, genetic predispositions to BCC have also been identified 1 . Atopic dermatitis (AD), a condition with a heritability that reaches 71-84%, might increase the risk of B
PMID 23927042

Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis.

von Neubeck C, Shankaran H, Geniza MJ, Kauer PM, Robinson RJ, Chrisler WB, Sowa MB.SourceGerman Cancer Consortium (DKTK), OncoRay - National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Integrative biology : quantitative biosciences from nano to macro.Integr Biol (Camb).2013 Aug 8. [Epub ahead of print]
The effects of low dose high linear energy transfer (LET) radiation on human health are of concern for space, occupational, and clinical exposures. As epidemiological data for such radiation exposures are scarce for making relevant predictions, we need to understand the mechanism of response especia
PMID 23925568

Bunker CB.SourceUniversity College London and Chelsea & Westminster Hospitals, London, Department of Dermatology, University College Hospital, 235 Euston Rd, London, NW1 2BU, UK.
The British journal of dermatology.Br J Dermatol.2013 Aug 2. doi: 10.1111/bjd.12553. [Epub ahead of print]
From their interesting data Becker et al (Br J Dermatol 2013;168:362-6) induce that … 'AD seems to be a priming precondition for the development of LS in boys' … consistent with … a permissive effect of atopy facilitating the development of LS' …. Not unreasonably, they continue … 'geneti
PMID 23909578

Optimization of filaggrin expression and processing in cultured rat keratinocytes

CHATTERJEA Sudeshna M.,RESING Katheryn A.,OLD William,NIRUNSUKSIRI Wilas,FLECKMAN Philip
Journal of dermatological science 61(1), 51-59, 2011-01-01
NAID 10030889754

SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing

Matsui Takeshi,Miyamoto Kenichi,Kubo Akiharu,Kawasaki Hiroshi,Ebihara Tamotsu,Hata Kazuya,Tanahashi Shinya,Ichinose Shizuko,Imoto Issei,Inazawa Johji,Kudoh Jun,Amagai Masayuki
EMBO MOLECULAR MEDICINE 3(6), 320-333, 2011-00-00
NAID 120005207232