プリブノーボックス
WordNet
- the quantity contained in a box; "he gave her a box of chocolates" (同)boxful
- evergreen shrubs or small trees (同)boxwood
- a rectangular drawing; "the flowchart contained many boxes"
- hit with the fist; "Ill box your ears!"
- the drivers seat on a coach; "an armed guard sat in the box with the driver" (同)box_seat
- private area in a theater or grandstand where a small group can watch the performance; "the royal box was empty" (同)loge
- a (usually rectangular) container; may have a lid; "he rummaged through a box of spare parts"
- a blow with the hand (usually on the ear); "I gave him a good box on the ear"
- any one of several designated areas on a ball field where the batter or catcher or coaches are positioned; "the umpire warned the batter to stay in the batters box"
- separate partitioned area in a public place for a few people; "the sentry stayed in his box to avoid the cold"
- put into a box; "box the gift, please" (同)package
- engage in a boxing match
- enclosed in or set off by a border or box; "boxed sections of the report"; "boxed announcements in the newspaper"
- enclosed in or as if in a box; "boxed cigars"; "a confining boxed-in space"; "felt boxed in by the traffic" (同)boxed-in, boxed in
- fighting with the fists (同)pugilism, fisticuffs
PrepTutorEJDIC
- 『箱』 / (の…)『1箱』《+『of』+『名』》 / (劇場などの)さじき席 ます席 / 番小屋,詰め所 / (野球で)バッターボックス;コーチャーズボックス;ピッチャーズマウンド;キャッチャーの定位置 / (線で囲った)四角のわく,囲み;(新聞・雑誌の) / (郵便の)私書箱 / 《the box》《英俗》テレビ / …'を'箱に入れる,箱詰めにする
- 〈C〉(平手・こぶしの)びんた,張り手,ひと打ち / 〈人〉‘と'ボクシングをする / …'を'平手で打つ,こぶしでなぐる / (…と)ボクシングをする《+『with』(『against』)+『名』》
- 〈C〉〈U〉ツゲ(常緑低木) / 〈U〉=boxwood
- 『ボクシング』
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/11/18 17:12:56」(JST)
[Wiki en表示]
The Pribnow box (also known as the Pribnow-Schaller box) is the sequence TATAAT of six nucleotides (thymine-adenine-thymine-etc.) that is an essential part of a promoter site on DNA for transcription to occur in bacteria.[1][2] It is an idealized or consensus sequence—that is, it shows the most frequently occurring base at each position in a large number of promoters analyzed; individual promoters often vary from the consensus at one or more positions. It is also commonly called the -10 sequence, because it is centered roughly 10 base pairs upstream from the site of initiation of transcription.
The Pribnow box has a function similar to the TATA box that occurs in promoters in eukaryotes and archaea: it is recognized and bound by a subunit of RNA polymerase during initiation of transcription. This region of the DNA is also the first place where base pairs separate during prokaryotic transcription to allow access to the template strand. The AT-richness is important to allow this separation, since adenine and thymine are easier to break apart (not due to the hydrogen bond count[3]).
It is named after David Pribnow and Heinz Schaller.[1][2]
Probability of occurrence of each nucleotide[4]
T |
A |
T |
A |
A |
T |
82% |
89% |
52% |
59% |
49% |
89% |
See also
References
- ^ a b Pribnow, David (March 1975). "Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter". PNAS 72 (3): 784–788. doi:10.1073/pnas.72.3.784. ISSN 1091-6490. PMC 432404. PMID 1093168. //www.ncbi.nlm.nih.gov/pmc/articles/PMC432404/.
- ^ a b Schaller, Heinz; Gray, Christopher; Herrman, Karin (February 1975). "Nucleotide sequence of an RNA polymerase binding site from the DNA of Bacteriophage fd". PNAS 72 (2): 737–741. doi:10.1073/pnas.72.2.737. ISSN 1091-6490. PMC 432391. PMID 1054851. //www.ncbi.nlm.nih.gov/pmc/articles/PMC432391/.
- ^ Yakovchuk, Peter; Protozanova, Ekaterina; Frank-Kamenetskii, Maxim D. (January 2006). "Base-stacking and base-pairing contributions into thermal stability of the DNA double helix". Nucleic Acids Research 34 (2): 564–574. doi:10.1093/nar/gkj454. ISSN 0305-1048. PMC 1360284. PMID 16449200. http://nar.oxfordjournals.org/content/34/2/564.long.
- ^ Harley, Calvin B.; Reynolds, Robert P. (March 1987). "Analysis of E. coli promoter sequences" (PDF, 0.9 MB). Nucleic Acids Research 15 (5): 2343–2361. doi:10.1093/nar/15.5.2343. ISSN 0305-1048. PMC 340638. PMID 3550697. http://nar.oxfordjournals.org/content/15/5/2343.long.
Transcription (Prokaryotic, Eukaryotic)
|
|
Transcriptional regulation |
prokaryotic
|
Operon (lac operon, trp operon, gal operon) · Repressor (lac repressor, trp repressor)
|
|
eukaryotic
|
Histone-modifying enzymes (histone/nucleosome): Histone methylation/Histone methyltransferase (EZH2) · Histone demethylase · Histone acetylation and deacetylation (Histone deacetylase HDAC1 · Histone acetyltransferase)
DNA methylation (DNA methyltransferase)
Chromatin remodeling: CHD7
|
|
both
|
Transcription coregulator (Coactivator, Corepressor) · Inducer
|
|
|
Promotion |
Promoter (Pribnow box, TATA box, BRE, CAAT box, Response element) · Enhancer (E-box, Response element) · Insulator · Silencer
|
|
Initiation (prokaryotic,
eukaryotic) |
Transcription start site
|
|
Elongation |
prokaryotic RNA polymerase: rpoB
eukaryotic RNA polymerase: RNA polymerase II
|
|
Termination
(prokaryotic,
eukaryotic) |
Terminator · Intrinsic termination · Rho factor
|
|
see also disorders of transcription and post transcriptional modification
B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)
|
|
UpToDate Contents
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English Journal
- Natural IS711 insertion causing omp31 gene inactivation in Brucella ovis.
- Gyuranecz M1, Kreizinger Z, Horváth G, Rónai Z, Dán A, Nagy B, Szeredi L, Makrai L, Jánosi S, Hajtós I, Magyar T, Bhide M, Erdélyi K, Dénes B.
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.J Vet Diagn Invest.2013 Mar;25(2):234-8. doi: 10.1177/1040638712474815. Epub 2013 Feb 12.
- The present report describes an atypical Brucella ovis strain (Bo10) isolated from the epididymis and testis of an infected ram. Macroscopic and microscopic lesions characteristic for the infection, including positive Brucella immunostaining, were observed within lesions in the genital organs. Compa
- PMID 23404477
- Structural and biophysical studies on two promoter recognition domains of the extra-cytoplasmic function sigma factor sigma(C) from Mycobacterium tuberculosis.
- Thakur KG1, Joshi AM, Gopal B.
- The Journal of biological chemistry.J Biol Chem.2007 Feb 16;282(7):4711-8. Epub 2006 Dec 4.
- sigma factors are transcriptional regulatory proteins that bind to the RNA polymerase and dictate gene expression. The extracytoplasmic function (ECF) sigma factors govern the environment dependent regulation of transcription. ECF sigma factors have two domains sigma(2) and sigma(4) that recognize t
- PMID 17145760
- Increased resistance to beta-lactams in a Klebsiella pneumoniae strain: role of a deletion downstream of the Pribnow box in the blaSHV-1 promoter.
- Corvec S1, Caroff N, Cosano D, Dauvergne S, Drugeon H, Reynaud A.
- International journal of antimicrobial agents.Int J Antimicrob Agents.2006 Oct;28(4):308-12. Epub 2006 Sep 7.
- Two hundred and five isolates of Klebsiella pneumoniae were collected from Nantes University Hospital in 2002. A new 30bp deletion was detected downstream of the -10 box of the SHV-1 promoter in a clinical K. pneumoniae isolate with a high amoxicillin/clavulanic acid minimum inhibitory concentration
- PMID 16956751
Japanese Journal
- Transferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow box
- Molecular Cloning and Nucleotide Sequence of the Pectate Lyase Gene from Pseudomonas marginalis N6301
- Bioscience, Biotechnology, and Biochemistry 57(6), 957-960, 1993-06-23
- NAID 110002676387
- Complete Nucleotide Sequence of Bacil-lus subtilis(natto)Plasmid Responsi-ble for γ-Polyglutamate Synthesis
Related Links
- The first, the pribnow box, is at about 10 and has the consensus sequence 5' TATAAT 3'. The second, the 35 sequence, ...
- ho·me·o·box (hō'mē-ō-boks), A highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes; it encodes a DNA-binding domain that allows the homeobox proteins to bind to and regulate gene ...
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