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1. 卵細胞質内精子注入法 intracytoplasmic sperm injection
2. NK細胞欠損症候群：臨床症状および診断 nk cell deficiency syndromes clinical manifestations and diagnosis
3. 体外受精（IFV） in vitro fertilization

English Journal

Gingival fibroblast responsiveness is differentially affected by Porphyromonas gingivalis: implications for the pathogenesis of periodontitis.

Scheres N, Crielaard W.SourceDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands.
Molecular oral microbiology.Mol Oral Microbiol.2013 Jun;28(3):204-18. doi: 10.1111/omi.12016. Epub 2012 Dec 26.
In periodontitis, tissue damage results mainly from aberrant host responses to oral microorganisms. Fibroblasts can play an important role in this. Gingival fibroblasts do not develop tolerance against the lipopolysaccharide of Porphyromonas gingivalis, a keystone pathogen in periodontitis, which ma
PMID 23279858

Crotonaldehyde-exposed macrophages induce IL-8 release from airway epithelial cells through NF-κB and AP-1 pathways.

Yang BC, Yang ZH, Pan XJ, Xiao FJ, Liu XY, Zhu MX, Xie JP.SourceDalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning 116023, PR China; Zhengzhou Tobacco Research Institute of CNTC, 2 Fengyang Road, Zhengzhou, Henan 450001, PR China.
Toxicology letters.Toxicol Lett.2013 May 10;219(1):26-34. doi: 10.1016/j.toxlet.2013.02.018. Epub 2013 Feb 28.
Crotonaldehyde, a highly toxic α, β-unsaturated aldehyde, is a major component of cigarette smoke and a ubiquitous environmental pollutant. Crotonaldehyde exposure is known to have adverse effects on respiratory health, but the underlying mechanisms remain obscure. To examine the interaction betwe
PMID 23458894

Involvement of heat shock protein 70 in the DNA protective effect from estrogen.

Dong Y, Wang Y, Yu H, Liu Y, Yang N, Zuo P.Source1School of Medicine, Yunnan University, Kunming, Yunnan, China.
American journal of Alzheimer's disease and other dementias.Am J Alzheimers Dis Other Demen.2013 May;28(3):269-77. doi: 10.1177/1533317513481096. Epub 2013 Mar 25.
As an endogenous cytoprotective factor, the protection of estrogen and heat shock protein-70 (Hsp70) on DNA has been documented, respectively, but the functional interaction between estrogen and Hsp70 on DNA damage repair is largely unknown. We therefore investigated the relation between estrogen an
PMID 23528882

木村友美,内山真一郎
東京女子医科大学雑誌 84(E1), E111-E117, 2014-01-31
… in vitro におけるシロスタゾール、GP IIb/IIIa阻害薬FK419およびtirofibanの血液レオロジーに及ぼす影響を検討した.,健常人より採取した全血にシロスタゾール1〜40μM、FK419 10〜1000nM、tirofiban 10〜1000nMを加えてpreincubation後、adenosine 5'-diphosphate(ADP)1μM、血小板活性化因子(PAF)0.1μMまたは N-formyl-methionyl-leucil-phenylalanine(FMLP)1μMを添加し、100μlの全血通過速度(μl/秒)をMC-FANを用いて測定した.,シロスタゾール、 FK419、tirofiban投与群 …
NAID 110009752563

NAKAGATA Naomi,TAKEO Toru,FUKUMOTO Kiyoko,HARUGUCHI Yukie,KONDO Tomoko,TAKESHITA Yumi,NAKAMUTA Yuko,UMENO Tomoko,TSUCHIYAMA Shuuji
Journal of Reproduction and Development, 2014
… In this study, we cryopreserved mouse sperm via various methods and performed in vitro fertilization (IVF) in which the combination of methyl-beta-cyclodextrin for sperm preincubation and reduced glutathione for insemination was used (the MBCD-GSH IVF). …
NAID 130003390825

CCL2/CCR2 augments the production of transforming growth factor-beta1, type 1 collagen and CCL2 by human CD45-/collagen 1-positive cells under high glucose concentrations

Hara Akinori,Sakai Norihiko,Furuichi Kengo,Sakai Yoshio,Takeya Motohiro,Bucala Richard,Mukaida Naofumi,Takuwa Yoh,Matsushima Kouji,Kaneko Shuichi,Wada Takashi
Clinical and Experimental Nephrology 17(6), 793-804, 2013-12
… Preincubation of the cells with cytochalasin B (a GLUT inhibitor) or N-acetylcysteine (an antioxidant) blocked the stimulatory effect of high glucose concentrations on these profibrotic molecules. … In addition, preincubation of the cells with CCL2 enhanced the high glucose-induced upregulation of TGF-β1, pro-COL1A1 and CCL2 and migration of the cells, and this effect was partly inhibited by treatment with CCR2 inhibitors. …
NAID 120005368211