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English Journal

Identification and characterization of a novel mammalian isoform of the endocytic adaptor ITSN1.

Dergai M, Skrypkina I, Dergai O, Tsyba L, Novokhatska O, Filonenko V, Drobot L, Rynditch A.SourceDepartment of Functional Genomics, Institute of Molecular Biology and Genetics, 150 Zabolotnogo Street, Kyiv 03680, Ukraine.
Gene.Gene.2011 Oct 10;485(2):120-9. Epub 2011 Jun 25.
Intersectin 1 (ITSN1) is an evolutionarily conserved adaptor protein engaged in clathrin-mediated endocytosis, cell signaling and actin cytoskeleton rearrangements. Two major ITSN1 isoforms were initially described, the ubiquitous short isoform (ITSN1-s) and the long isoform (ITSN1-l) expressed pred
PMID 21712076

Long SW, Ooi JY, Yau PM, Jones PL.SourceDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, B107 Chemical and Life Sciences Laboratory, Urbana, IL 61801, USA.
Bioscience reports.Biosci Rep.2011 Oct 1;31(5):333-43.
Mutations in MECP2 (methyl-CpG-binding protein 2) are linked to the severe postnatal neurodevelopmental disorder RTT (Rett syndrome). MeCP2 was originally characterized as a transcriptional repressor that preferentially bound methylated DNA; however, recent results indicate MeCP2 is a multifunctiona
PMID 21070191