多感覚特性侵害受容器
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English Journal
- Proton block of proton-activated TRPV1 current.
- Lee BH1, Zheng J2.
- The Journal of general physiology.J Gen Physiol.2015 Jul 13. pii: jgp.201511386. [Epub ahead of print]
- The TRPV1 cation channel is a polymodal nociceptor that is activated by heat and ligands such as capsaicin and is highly sensitive to changes in extracellular pH. In the body core, where temperature is usually stable and capsaicin is normally absent, H+ released in response to ischemia, tissue injur
- PMID 26170176
- Cav3.2-expressing low-threshold C fibres in human hairy skin contribute to cold allodynia-a non-TRPV1- and non-TRPM8-dependent phenomenon.
- Samour MS1, Nagi SS, Mahns DA.
- Pain.Pain.2015 Aug;156(8):1566-1575.
- It is generally agreed that cold allodynia is a consequence of impaired (Aδ-fibre-mediated) central inhibition of C-nociceptive inputs. However, it is also known that C polymodal nociceptors are not activated at innocuous low temperatures. Recently, we demonstrated the contribution of C-tactile fib
- PMID 25932689
- Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site.
- Wang S1, Joseph J, Ro JY, Chung MK.
- Pain.Pain.2015 May;156(5):931-41. doi: 10.1097/j.pain.0000000000000134.
- TRPV1 is a nociceptive ion channel activated by polymodal stimuli such as capsaicin, proton, and noxious heat. Multiple inflammatory mediators activate protein kinases, especially protein kinase C (PKC), which phosphorylates TRPV1. Emerging evidence suggests that phosphorylation of TRPV1 constitutes
- PMID 25734989
Japanese Journal
- ＥＲＣＰ後すい炎のすい性とう痛の発生機序とペインコントロール
- 明石 隆吉,浜田 知久馬
- 膵臓 20(1), 1-9, 2005
- … すなわち, SIRS項目陽性例は有意に"強い腹痛"を訴える例が多く, 重症化しやすいことが判明した.膵性疼痛はトリプシン, サイトカイン (TNF-α), PAR-2, アラキドン酸カスケード, polymodal-nociceptorのカスケード反応により惹起される. …
- NAID 130004495647
- 痛み受容器(侵害受容器)の生理学 : 痛み受容器における受容変換・感作の機構
- 水村 和枝
- The journal of the Japan Society of Pain Clinicians = 日本ペインクリニック学会誌 9(4), 400-406, 2002-10-25
- 痛みは, 痛み刺激 (侵害刺激) が侵害受容器によって電気的な信号 (活動電位) に変換されたうえ, 末梢求心神経軸索上を伝達され, さらにその情報が脊髄, 視床を経て大脳皮質まで伝達されて痛みとして感じられる. 各種の刺激が痛みの受容器終末に到達したとき, 最初に起こることは電気的変化 (受容器電位) を生じることである. この変換を行うトランスジューサー, イオンチャネルについての研究の現状を …
- NAID 10010308247
- 佐藤 純,鈴木 義明,河西 稔,水村 和枝
- 末梢神経 = Peripheral nerve 12(1), 137-140, 2002-05-31
- NAID 10020439852
Related Links
- Polymodal Nociceptors, Heat Transduction C AROLINA R OZA Polymodal Sensory Neurones Mechanoheat Nociceptor Muscle Nociceptor Nociceptor Nociceptor Accommodation Nociceptor Adaptation Nociceptor Desensitization ...
- polymodal nociceptor a nociceptor of unmyelinated nerve fibers, activated by several different types of stimuli such as heat, mechanical pressure, or chemical ... Look at other dictionaries: Nociceptor — A nociceptor is a sensory ...
★リンクテーブル★
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- 英
- polymodal nociceptor
- 同
- ポリモーダル侵害受容器、多モード侵害受容器
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- 関
- multimodal、multimodality