WordNet

an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/30 06:56:44」(JST)

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Structure of Taq DNA polymerase

A polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains or polymers of nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA or RNA template strand using base-pairing interactions.

It is an accident of history that the enzymes responsible for the generation of other biopolymers are not also referred to as polymerases. For example, the enzymatic complex that assembles amino acids into proteins is termed the ribosome, rather than "protein polymerase".

A polymerase from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is used in the polymerase chain reaction, an important technique of molecular biology.

Other well-known polymerases include:

Terminal Deoxynucleotidyl Transferase (TDT), which lends diversity to antibody heavy chains

Reverse Transcriptase, an enzyme used by RNA retroviruses like HIV, which is used to create a complementary strand to the preexisting strand of viral RNA before it can be integrated into the DNA of the host cell. It is also a major target for antiviral drugs.

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4. 遺伝学およびゲノミクスのためのツール：ポリメラーゼ連鎖反応 tools for genetics and genomics polymerase chain reaction
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English Journal

Association of cytotoxic T-lymphocyte antigen 4 gene with immune thrombocytopenia in Chinese Han children.

Yao L1, Liu B2, Jiang L3, Zhou L4, Liu X5.
Hematology (Amsterdam, Netherlands).Hematology.2019 Dec;24(1):123-128. doi: 10.1080/10245332.2018.1530179. Epub 2018 Oct 14.
PMID 30319055

Relationship between genetic polymorphism of MTHFR C677T and lower extremities deep venous thrombosis.

Xu J1, Li K2, Zhou W1.
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Cross-sectional physician survey on the use of minimal residual disease testing in the management of pediatric and adult patients with acute lymphoblastic leukemia.

Kim C1, Delaney K2, McNamara M2, Chia V1, Romanov V3.
Hematology (Amsterdam, Netherlands).Hematology.2019 Dec;24(1):70-78. doi: 10.1080/10245332.2018.1510068. Epub 2018 Aug 21.
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Japanese Journal

感染症診断における遺伝子検査の進歩と実践 (特集よくわかる小児感染症の基礎知識) -- (診断編)

大楠清文
小児科診療 78(5), 619-626, 2015-05
NAID 40020446743

酵素による遺伝子増幅反応を目的としたマイクロチューブ加熱用共振器とその電磁界解析 (マイクロ波)

吉村武朗,花井孝真,峯木茂 [他]
電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 115(4), 71-76, 2015-04-16
NAID 40020459644

酵素による遺伝子増幅反応を目的としたマイクロチューブ加熱用共振器とその電磁界解析 (無線電力伝送)

吉村武朗,花井孝真,峯木茂 [他]
電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 115(3), 71-76, 2015-04-16
NAID 40020459456

「ポリメラーゼ」

　　[★]

英: polymerase
関: 重合酵素

「DNA-directed RNA polymerase」

　　[★]

DNA依存性RNAポリメラーゼ、DNA指向性RNAポリメラーゼ

関: DNA-dependent RNA polymerase、RNA polymerase、transcriptase

「DNA-dependent RNA polymerase II」

　　[★]

DNA依存性RNAポリメラーゼII

関: RNA polymerase II

「RNA-dependent RNA polymerase」

　　[★]

RNA依存性RNA・リメラーゼ

関: RNA replicase

「RNA-directed DNA polymerase」

　　[★] RNA指向性DNAポリメラーゼ

「inhibitor of DNA polymerase」

　　[★] DNAポリメラーゼ阻害剤

リンク元	「ポリメラーゼ」
拡張検索	「DNA-directed RNA polymerase」「DNA-dependent RNA polymerase II」「RNA-dependent RNA polymerase」「RNA-directed DNA polymerase」「inhibitor of DNA polymerase」

匿名

検索

案内

案内

polymerase