photoallergy

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/16 11:16:31」(JST)

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Sun poisoning
An image of a patch of sun poisoning on the left forearm
Classification and external resources
ICD-10	L57.8
ICD-9	692.79
DiseasesDB	24609
MeSH	D010787

Photodermatitis, sometimes referred to as sun poisoning or photoallergy, is a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Signs and symptoms

Photodermatitis may result in swelling, a burning sensation, a red itchy rash sometimes resembling small blisters, and peeling of the skin. Nausea may also occur. There may also be blotches where the itching may persist for long periods of time. In these areas an unsightly orange to brown tint may form, usually near or on the face.

Causes

Many medications and conditions can cause sun sensitivity, including:

• Sulfa used in some drugs, among them some antibiotics, diuretics, COX-2 inhibitors, and diabetes drugs.
• Psoralens, coal tars, photo-active dyes (eosin, acridine orange)
• Musk ambrette, methylcoumarin, lemon oil (may be present in fragrances)
• PABA (found in sunscreens)
• Oxybenzone (UVA and UVB chemical blocker also in sunscreens)
• Salicylanilide (found in industrial cleaners)
• St John's Wort, used to treat clinical depression
• Hexachlorophene (found in some ℞ antibacterial soaps)
• Contact with sap from Giant Hogweed. Common Rue (Ruta graveolins) is another phototoxic plant commonly found in gardens
• Tetracycline antibiotics (e.g., tetracycline, doxycycline, minocycline)
• Benzoyl peroxide
• Retinoids (e.g., isotretinoin)
• Some NSAIDs (e.g., ibuprofen, naproxen sodium)
• Fluoroquinolone antibiotic: Sparfloxacin in 2% of cases
• Amiodarone, used to treat atrial fibrillation
• Pellagra

Photo dermatitis can also be caused by plants like the Dictamnus (commonly known as the "Burning Bush") which is a genus of the flowering plant in the Rutaceae family. This is called phytophotodermatitis.

Prevention

Prevention includes avoiding exposure to the sun and wearing sun block on the affected area.

• Cover up: wear long sleeves, slacks, and a wide-brimmed hat whenever harsh exposure is probable
• Avoid chemicals that may trigger a reaction
• Wear sunscreen at least factor 30 with a high UVA protection level
• Wear gloves and/or remain indoors after handling fruits or plants which increase sensitivity to light

See also

• Light sensitivity
• Photosensitivity
• Solar urticaria

References

UpToDate Contents

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• 1. 光線過敏症（光線皮膚症）：臨床症状、診断、および治療 photosensitivity disorders photodermatoses clinical manifestations diagnosis and treatment
• 2. 皮膚光線過敏症の概要：光生物学、患者評価、および光保護 overview of cutaneous photosensitivity photobiology patient evaluation and photoprotection
• 3. 薬疹 drug eruptions
• 4. アレルギー性接触皮膚炎の臨床的特徴および診断 clinical features and diagnosis of allergic contact dermatitis
• 5. 従来の癌の化学療法による皮膚合併症 cutaneous complications of conventional chemotherapy agents

English Journal

• Photopatch testing in Asians: a 5-year experience in Singapore.

• Chuah SY, Leow YH, Goon AT, Theng CT, Chong WS.SourceDepartment of Dermatology, National Skin Centre, Singapore.
• Photodermatology, photoimmunology & photomedicine.Photodermatol Photoimmunol Photomed.2013 Jun;29(3):116-20. doi: 10.1111/phpp.12034.
• BACKGROUND: Photopatch testing is important for diagnosing photoallergic contact dermatitis. We aimed to evaluate the use of photopatch test at the National Skin Centre, Singapore.METHODS: All patients who had photopatch tests done between 2007 and 2011 at the National Skin Centre were included.RESU
• PMID 23651271

• [Phototoxic and photoallergic reactions].

• Neumann NJ, Schauder S.SourceUniversitätshautklinik der Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland, neumannt@uni-duesseldorf.de.
• Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete.Hautarzt.2013 May;64(5):354-62. doi: 10.1007/s00105-012-2512-y.
• Many artificial or naturally occurring substances are included under the term photosensitizer. After ultraviolet (UV) exposure such agents can lead to increased photosensitivity and subsequently to phototoxic or photoallergic reactions in the skin. From clinical observations and comprehensive studie
• PMID 23644473

• Photopatch testing: recommendations for a European photopatch test baseline series.

• Gonçalo M, Ferguson J, Bonevalle A, Bruynzeel DP, Giménez-Arnau A, Goossens A, Kerr A, Lecha M, Neumann N, Niklasson B, Pigatto P, Rhodes LE, Rustemeyer T, Sarkany R, Thomas P, Wilkinson M.SourceDepartment of Dermatology, Coimbra University Hospital, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. mmgoncalo@gmail.com
• Contact dermatitis.Contact Dermatitis.2013 Apr;68(4):239-43. doi: 10.1111/cod.12037.
• In order to establish a consensus recommendation for performing photopatch testing, a photopatch test taskforce group was established under the joint umbrella of the European Society for Contact Dermatitis and the European Society for Photodermatology in 2000. After proposing the most adequate metho
• PMID 23510344

Japanese Journal

• 光毒性リスク評価のためのreactive oxygen species (ROS) assayの開発とその改良 (特集 動物実験代替法を展望する)

• 尾上 誠良
• Fragrance journal 42(9), 45-49, 2014-09
• NAID 40020211439

• ヒドロクロロチアジド配合降圧薬による光線過敏型薬疹の8例 : 光毒性 ? 光アレルギー性 ? 光線テストによる作用機序の考察

• 車地 祐子
• Journal of environmental dermatology and cutaneous allergology = / the Japanese Society for Dermatoallergology and Contact Dermatitis 7(3), 177-186, 2013-07-31
• NAID 10031190566

• 新しい皮膚生理機能評価法による乾燥性口唇に対するリップクリームの有用性検討

• 西村 景子,矢上 晶子,佐野 晶代,小林 束,沼田 茂樹,高橋 正幸,三和 拓人,佐々木 りか子,福永 淳,錦織 千佳子,森田 栄伸,松永 佳世子
• 西日本皮膚科 75(6), 540-544, 2013
• 2010 年 11 月から 2011 年 5 月の間に藤田保健衛生大学病院，りかこ皮フ科クリニックおよび神戸大学医学部附属病院を受診したアトピー性皮膚炎，小児乾燥性皮膚炎，光線過敏症などの患者の中で口唇の乾燥を有する 50 例に対し，口唇の保湿と遮光を目的として「ノブ® リップケアクリーム UV」を 4 週間使用した。試験開始および終了時に口唇の皮膚所見を得るとともに角層水分量と経表皮水分蒸散量を …
• NAID 130004831846

Related Pictures

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★リンクテーブル★

リンク元	「光アレルギー」「photoallergic contact dermatitis」

「光アレルギー」

　　[★]

英

photoallergy

関

光接触皮膚炎、光アレルギー性皮膚炎、光アレルギー性接触皮膚炎

「photoallergic contact dermatitis」

　　[★]

光アレルギー性接触皮膚炎

関

photoallergic dermatitis、photoallergy、photocontact dermatitis