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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/09/23 12:50:17」(JST)
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Phosphorylethanolamine |
|
Identifiers |
CAS number |
1071-23-4 Y |
PubChem |
1015 |
ChemSpider |
990 Y |
DrugBank |
DB04403 |
MeSH |
phosphorylethanolamine |
ChEBI |
CHEBI:17553 Y |
ChEMBL |
CHEMBL146972 Y |
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InChI=1S/C2H8NO4P/c3-1-2-7-8(4,5)6/h1-3H2,(H2,4,5,6) Y
Key: SUHOOTKUPISOBE-UHFFFAOYSA-N Y
|
Properties |
Molecular formula |
C2H8NO4P |
Molar mass |
141.063 g/mol |
Appearance |
white powder |
Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
Infobox references |
Phosphorylethanolamine or phosphoethanolamine is an ethanolamine derivative that is used to construct sphingomyelins. This chemical possesses two pKa values: 5.61 and 10.39.[1] The amine group is only weakly acidic so it doesn't have any significant contribution in pKa values.
References[edit source | edit]
- ^ Myller, AT et al. 2010 Preparation of aminofunctionalized Ti02 surfaces by binding of organophosphates; Applied Surface Science 257,1616
Additional images[edit source | edit]
See also[edit source | edit]
- Phosphoserine
- Phosphocholine
UpToDate Contents
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English Journal
- Cyclen-based cationic lipids containing a pH-sensitive moiety as gene delivery vectors.
- Huang Z1, Liu YH, Zhang YM, Zhang J, Liu Q, Yu XQ.
- Organic & biomolecular chemistry.Org Biomol Chem.2015 Jan 14;13(2):620-30. doi: 10.1039/c4ob01856g. Epub 2014 Nov 5.
- A series of novel cationic lipids based on 1,4,7,10-tetrazacyclododecane (cyclen) with the imidazole group as the pH-sensitive moiety and various aliphatic long chains were designed and synthesized. Cationic liposomes were prepared by mixing the lipids and the helper lipid 1,2-dioleoyl-sn-glycero-3-
- PMID 25372457
- Stalk formation as a function of lipid composition studied by X-ray reflectivity.
- Khattari Z1, Köhler S2, Xu Y2, Aeffner S2, Salditt T3.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jan;1848(1 Pt A):41-50. doi: 10.1016/j.bbamem.2014.08.010. Epub 2014 Sep 28.
- We have investigated the structure and interaction of solid-supported multilamellar phospholipid bilayers in view of stalk formation as model systems for membrane fusion. The multi-component bilayers were composed of ternary and quaternary mixtures, containing phosphatidylcholines, phosphatidylethan
- PMID 25261611
- How polyunsaturated fatty acids modify molecular organization in membranes: Insight from NMR studies of model systems.
- Shaikh SR1, Kinnun JJ2, Leng X2, Williams JA2, Wassall SR3.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jan;1848(1PB):211-219. doi: 10.1016/j.bbamem.2014.04.020. Epub 2014 May 9.
- Marine long chain n-3 polyunsaturated fatty acids (PUFA), eicosapentaenoic (EPA) and docosahexaenoic acid (DHA), are bioactive molecules with clinical applications for the treatment of several diseases. In order to effectively translate these molecules into clinical trials, it is essential to establ
- PMID 24820775
Japanese Journal
- siRNA Delivery into Tumor Cells by Cationic Cholesterol Derivative-Based Nanoparticles and Liposomes
- , , [他], , , , , , ,
- Biological and Pharmaceutical Bulletin 38(1), 30-38, 2015
- … diamine-type cationic cholesteryl carbamate (OH-C-Chol, cholesteryl (2-((2-hydroxyethyl)amino)ethyl)carbamate) and triamine-type carbamate (OH-NC-Chol, cholesteryl (2-((2-((2-hydroxyethyl)amino)ethyl)amino)ethyl)carbamate), and prepared cationic nanoparticles composed of OH-C-Chol or OH-NC-Chol with Tween 80 (NP-C and NP-NC, respectively), as well as cationic liposomes composed of OH-C-Chol or OH-NC-Chol with 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) (LP-C and LP-NC, respectively) for evaluation of their possible use as siRNA delivery …
- NAID 130004872237
- An aptamer ligand based liposomal nanocarrier system that targets tumor endothelial cells
- Ara Mst Naznin,Matsuda Takashi,Hyodo Mamoru,Sakurai Yu,Hatakeyama Hiroto,Ohga Noritaka,Hida Kyoko,Harashima Hideyoshi
- Biomaterials 35(25), 7110-7120, 2014-08
- … We first synthesized an aptamer-polyethylene glycol 2000-distearoyl phosphoethanolamine (Apt-PEG(2000)-DSPE). …
- NAID 120005512022
- Purification, characterization, molecular cloning, and extracellular production of a novel bacterial glycerophosphocholine cholinephosphodiesterase from Streptomyces sanglieri(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Sugimori Daisuke,Ogasawara Junki,Okuda Koki,Murayama Kazutaka
- Journal of bioscience and bioengineering 117(4), 422-430, 2014-04
- … The enzyme exhibited specificity toward GPC and glycerol-3-phosphoethanolamine and hydrolyzed glycerol-3-phosphate and lysophosphatidylcholine. …
- NAID 110009817056
Related Links
- Phosphorylethanolamine or phosphoethanolamine is an ethanolamine derivative that is used to construct sphingomyelins. This chemical possesses two pKa values: 5.61 and 10.39. The amine group is only weakly acidic so it doesn't have ...
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