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the organic processes (in a cell or organism) that are necessary for life (同)metabolic_process

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Lipidome and proteome of lipid droplets from the methylotrophic yeast Pichia pastoris.

Ivashov VA, Grillitsch K, Koefeler H, Leitner E, Baeumlisberger D, Karas M, Daum G.SourceInstitute of Biochemistry, Graz University of Technology, Austria.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Feb;1831(2):282-90. doi: 10.1016/j.bbalip.2012.09.017. Epub 2012 Oct 4.
Lipid droplets (LD) are the main depot of non-polar lipids in all eukaryotic cells. In the present study we describe isolation and characterization of LD from the industrial yeast Pichia pastoris. We designed and adapted an isolation procedure which allowed us to obtain this subcellular fraction at
PMID 23041514

FoxO3a Negatively Regulates Nerve Growth Factor-Induced Neuronal Differentiation Through Inhibiting the Expression of Neurochondrin in PC12 Cells.

Wang H, Duan X, Ren Y, Liu Y, Huang M, Liu P, Wang R, Gao G, Zhou L, Feng Z, Zheng W.SourceNeuropharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
Molecular neurobiology.Mol Neurobiol.2013 Feb;47(1):24-36. doi: 10.1007/s12035-012-8357-7. Epub 2012 Oct 21.
Forkhead box O3 (FoxO3a) is a forkhead family transcription factor playing important roles in non-neuronal differentiation, metabolism, proliferation, and survival, but its role in neuronal differentiation remains unclear. In the present study, we investigated the role of FoxO3a in neuronal differen
PMID 23086522

Phosphatidylinositol 4-Kinases and PI4P Metabolism in the Nervous System: Roles in Psychiatric and Neurological Diseases.

Clayton EL, Minogue S, Waugh MG.SourceUCL Institute for Liver and Digestive Health, Royal Free Campus, Rowland Hill Street, London, NW3 2PF, UK.
Molecular neurobiology.Mol Neurobiol.2013 Feb;47(1):361-72. doi: 10.1007/s12035-012-8358-6. Epub 2012 Oct 10.
The four mammalian phosphatidylinositol 4-kinases, together with the PI(4,5)P(2) depleting 5-phosphatases of the oculocerebrorenal syndrome of Lowe and synaptojanin families, modulate neuronal pools of PI4P lipid and regulate intracellular membrane trafficking in the endocytic and secretory pathways
PMID 23054682

Hattori Kenji,Yamaguchi Nozomi,Umezawa Kazuo [他],Tamura Hiroomi
Biological and Pharmaceutical Bulletin 35(9), 1588-1593, 2012
… Steroid sulfatase (STS) plays an important role in steroid metabolism in which estrogens and dehydroepiandrosterone (DHEA) are produced from their sulfates. … This induction was completely inhibited by treatment with phosphatidylinositol (PI) 3-kinase inhibitors such as LY294002 or wortmannin, and by the nuclear factor-kappa B (NF-κB) inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ). …
NAID 130001872068

Expression and functions of myo-inositol monophosphatase family genes in seed development of Arabidopsis

Sato Yuko,Yazawa Katsumi,Yoshida Seiji [他],Tamaoki Masanori,Nakajima Nobuyoshi,Iwai Hiroaki,Ishii Tadashi,Satoh Shinobu,岩井宏暁,佐藤忍
Journal of plant research 124(3), 385-394, 2011-05-01
… IMP is also important in phosphate metabolism and is required for the biosynthesis of cell wall polysaccharides, phytic acid, and phosphatidylinositol. …
NAID 10028258177

Roles of Cyclic Adenosine Monophosphate Signaling in Endothelial Cell Differentiation and Arterial-Venous Specification During Vascular Development

YAMAMIZU Kohei,YAMASHITA Jun K.
Circulation journal : official journal of the Japanese Circulation Society 75(2), 253-260, 2011-01-25
… Cyclic adenosine monophosphate (cAMP) is an important second messenger mediating physiological functions, including metabolism, gene expression, cell growth and differentiation. … On the other hand, cAMP can activate phosphatidylinositol-3 kinase, which induces an arterial fate in vascular progenitors via dual activation of Notch and β-catenin signaling as an arterial-specific machinery. …
NAID 10027426508