English Journal

Catecholamine secretion by chemical hypoxia in guinea-pig, but not rat, adrenal medullary cells: Differences in mitochondria.

Harada K1, Endo Y1, Warashina A1, Inoue M2.
Neuroscience.Neuroscience.2015 Aug 20;301:134-43. doi: 10.1016/j.neuroscience.2015.05.080. Epub 2015 Jun 3.
The effects of mitochondrial inhibitors (CN(-), a complex IV inhibitor and CCCP, protonophore) on catecholamine (CA) secretion and mitochondrial function were explored functionally and biochemically in rat and guinea-pig adrenal chromaffin cells. Guinea-pig chromaffin cells conspicuously secreted CA
PMID 26047729

A case of sudden death after ultrasound-guided percutaneous alcohol injection of a paraganglioma mis-diagnosed as a peri-renal cyst.

Andrello L1, Visonà SD2, Osculati A1.
Forensic science international.Forensic Sci Int.2015 Aug;253:e20-4. doi: 10.1016/j.forsciint.2015.05.019. Epub 2015 Jun 6.
Paragangliomas are cromaffin tumors arising from the neural crest cells of parasympathetic or sympathetic ganglia. They are known to be rare causes of sudden death. Here we present the autopsy findings, as well as microscopical and immunohistochemistry study, of a 48-years-old woman who died suddenl
PMID 26055308

Enhanced BDNF signalling following chronic hypoxia potentiates catecholamine release from cultured rat adrenal chromaffin cells.

Scott AL1, Zhang M1, Nurse CA1.
The Journal of physiology.J Physiol.2015 Aug 1;593(15):3281-3299. doi: 10.1113/JP270725.
KEY POINTS: We investigated the role of the neurotrophin BDNF signalling via the TrkB receptor in rat adrenomedullary chromaffin cells (AMCs) exposed to normoxia (Nox; 21% O2 ) and chronic hypoxia (CHox; 2% O2 ) in vitro for ∼48 h. TrkB receptor expression was upregulated in primary AMCs and in i
PMID 26095976