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English Journal

Proteomic profile of aminoglutethimide-induced apoptosis in HL-60 cells: Role of myeloperoxidase and arylamine free radicals.

Khan SR1, Baghdasarian A1, Nagar PH2, Fahlman R2, Jurasz P1, Michail K1, Aljuhani N3, Siraki AG4.
Chemico-biological interactions.Chem Biol Interact.2015 Sep 5;239:129-38. doi: 10.1016/j.cbi.2015.06.020. Epub 2015 Jun 20.
In this study, the cellular effects resulting from the metabolism of aminoglutethimide by myeloperoxidase were investigated. Human promyelocytic leukemia (HL-60) cells were treated with aminoglutethimide (AG), an arylamine drug that has a risk of adverse drug reactions, including drug-induced agranu
PMID 26102013

Kim CD1, Cha JD2, Li S3, Cha IH4.
Archives of oral biology.Arch Oral Biol.2015 Sep;60(9):1283-98. doi: 10.1016/j.archoralbio.2015.05.009. Epub 2015 Jun 8.
BACKGROUND: Acacetin (5,7-dihydroxy-40-methoxyflavone), present in safflower seeds, plants, flowers, Cirisium rhinoceros Nakai, has been reported to be able to exert anti-peroxidative, anti-inflammatory, anti-plasmodial, and anti-proliferative activities by inducing apoptosis and blocking the progre
PMID 26099663

Aloe vera affects changes induced in pulmonary tissue of mice caused by cigarette smoke inhalation.

Koul A1, Bala S1, Yasmeen1, Arora N1.
Environmental toxicology.Environ Toxicol.2015 Sep;30(9):999-1013. doi: 10.1002/tox.21973. Epub 2014 Feb 24.
This study was undertaken to determine the influence of Aloe vera (AV) on changes induced in pulmonary tissue of cigarette smoke (CS) inhaling mice. CS inhalation for 4 weeks caused pulmonary damage as evident by histoarchitectural alterations and enhanced serum and tissue lactate dehydrogenase (LDH
PMID 24615921