Observed octameric assembly of a Plasmodium yoelii peroxiredoxin can be explained by the replacement of native "ball-and-socket" interacting residues by an affinity tag.
Gretes MC, Karplus PA.SourceDepartment of Biochemistry & Molecular Biology, Oregon Health & Science University, Portland, Oregon, 97239; Department of Biochemistry & Biophysics, Oregon State University, Corvallis, Oregon, 97331.
Protein science : a publication of the Protein Society.Protein Sci.2013 Oct;22(10):1445-52. doi: 10.1002/pro.2328.
Peroxiredoxins (Prxs) are ubiquitous and efficient antioxidant enzymes crucial for redox homeostasis in most organisms, and are of special importance for disease-causing parasites that must protect themselves against the oxidative weapons of the human immune system. Here, we describe reanalyses of c
Ablation of Peroxiredoxin II Attenuates Experimental Colitis by Increasing FoxO1-Induced Foxp3+ Regulatory T Cells.
Won HY, Jang EJ, Lee K, Oh S, Kim HK, Woo HA, Kang SW, Yu DY, Rhee SG, Hwang ES.SourceCollege of Pharmacy and Global Top 5 Research Program, Ewha Womans University, Seoul 120-750, Korea.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2013 Sep 18. [Epub ahead of print]
Peroxiredoxin (Prx) II is an intracellular antioxidant molecule that eliminates hydrogen peroxide, employing a high substrate-binding affinity. PrxII deficiency increases the levels of intracellular reactive oxygen species in many types of cells, which may increase reactive oxygen species-mediated i
Molecular Basis for the Resistance of Human Mitochondrial 2-Cys Peroxiredoxin 3 to Hyperoxidation.
Haynes AC, Qian J, Reisz JA, Furdui CM, Lowther WT.SourceWake Forest School of Medicine, United States.
The Journal of biological chemistry.J Biol Chem.2013 Sep 3. [Epub ahead of print]
Peroxiredoxins (Prxs) detoxify peroxides and modulate H2O2-mediated cell signaling in normal and numerous pathophysiological contexts. The typical 2-Cys subclass of Prxs (human Prx1-4) utilize a Cys sulfenic acid (Cys-SOH) intermediate and disulfide bond formation across two subunits during catalysi
Disruption of Glutathione Homeostasis Causes Accumulation of <i>S</i>-Glutathionyl Proteins in Response to Exposure to Reactive Oxygen Species in Human Erythrocytes
KEY WORDS: hyperoxidation, oxygen consumption, flavonoid phenols, oxidative aging, browning, flavor stability. The very first experiments on must hyperoxidation were reported in the 1970s [37,38,39]. Traditionally, careful protection of must ...
Hyperoxidation - Meaning and definition. ... hyperoxidation. Excessive oxidation. . .. (05 Mar 2000) ... Found op http://www.mondofacto.com/facts/dictionary? hyperoxidation. hyperoxidation. Type: Term Pronunciation: hī′pĕr-oks′i-dā′ shŭn ...