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Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/11/09 14:44:26」(JST)
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A pentamer is an entity composed of five sub-units.
In chemistry, it applies to molecules made of five monomers.
In biochemistry, it applies to macromolecules, in particular to pentameric proteins, made of five proteic sub-units.
In microbiology, a pentamer is one of the proteins composing the polyhedral protein shell that encloses the bacterial micro-compartments known as carboxysomes.
In immunology, an MHC Pentamer is a reagent used to detect antigen-specific CD8+ T cells.
See also
|
Wikimedia Commons has media related to Pentamers. |
- penta prefix
- -mer suffix
- Pentamerous Metamorphosis, an album by Global Communication
- Pentamery (botany), a characteristic of plants having five petals (pentamerous flowers).
- Pentamerous can also refer to animals, such as crinoids
UpToDate Contents
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English Journal
- Phylogenetic conservation of protein-lipid motifs in pentameric ligand-gated ion channels.
- Barrantes FJ1.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Sep;1848(9):1796-805. doi: 10.1016/j.bbamem.2015.03.028. Epub 2015 Mar 31.
- Using the crosstalk between the nicotinic acetylcholine receptor (nAChR) and its lipid microenvironment as a paradigm, this short overview analyzes the occurrence of structural motifs which appear not only to be conserved within the nAChR family and contemporary eukaryotic members of the pentameric
- PMID 25839355
- Nicotinic acetylcholine receptor-lipid interactions: Mechanistic insight and biological function.
- Baenziger JE1, Hénault CM2, Therien JP2, Sun J2.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Sep;1848(9):1806-17. doi: 10.1016/j.bbamem.2015.03.010. Epub 2015 Mar 16.
- Membrane lipids are potent modulators of the nicotinic acetylcholine receptor (nAChR) from Torpedo. Lipids influence nAChR function by both conformational selection and kinetic mechanisms, stabilizing varying proportions of activatable versus non-activatable conformations, as well as influencing the
- PMID 25791350
- The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation.
- Cecchini M1, Changeux JP2.
- Neuropharmacology.Neuropharmacology.2015 Sep;96(Pt B):137-49. doi: 10.1016/j.neuropharm.2014.12.006. Epub 2014 Dec 18.
- Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a chemical messenger - a neurotransmitter - into an ion flux through the postsynaptic membrane. Here, we present an overview of the most recent advance
- PMID 25529272
Japanese Journal
- Cysteine Residues in the Major Capsid Protein, Vp1, of the JC Virus Are Important for Protein Stability and Oligomer Formation
- Kobayashi Shintaro,Suzuki Tadaki,Igarashi Manabu,Orba Yasuko,Ohtake Noriko,Nagakawa Keita,Niikura Kenichi,Kimura Takashi,Kasamatsu Harumi,Sawa Hirofumi
- PLoS One 8(10), e76668, 2013-10-09
- … The capsid of the human polyomavirus JC virus (JCV) consists of 72 pentameric capsomeres of a major structural protein, Vp1. …
- NAID 120005350093
- Expression and Secretion of Cholera Toxin B Subunit in Lactobacilli
- Okuno Takahiro,Kashige Nobuhiro,Satho Tomomitsu [他],Irie Keiichi,Hiramatsu Yukihiro,Sharmin Tanjina,Fukumitsu Yuki,Uyeda Saori,Yamada Seitaro,Harakuni Tetsuya,Miyata Takeshi,Arakawa Takeshi,Imoto Masumi,Toda Akihisa,Nakashima Yukihiko,Miake Fumio
- Biological and Pharmaceutical Bulletin 36(6), 952-958, 2013
- … The pentameric cholera toxin B (CTB) subunit has no toxicity, and is used as an antigen in cholera vaccines and as a delivery molecule in vaccines to various diseases. …
- NAID 130003361440
- Anti-Angiogenesis Activities of Novel Peptide Complexes: Mitochondria-Disruptive 9mer Peptides Conjugated with the Integrin alpha V beta 3-Homing Cyclic RGD Motif
- IWASAKI Takashi,YAMAKAWA Minoru,ASAOKA Ai,KAWANO Tsuyoshi,ISHIBASHI Jun
- Bioscience, Biotechnology, and Biochemistry 76(11), 2044-2048, 2012
- … We investigated the specific delivery and pharmacological potential of enantiomeric mitochondria-disruptive peptides (RLYLRIGRR-NH2, RLRLRIGRR-NH2, ALYLAIRRR-NH2, and RLLLRIGRR-NH2) after conjugation with an integrin αVβ3-homing peptide, cyclic pentameric RGD peptide. …
- NAID 130004137845
Related Links
- A] receptors are pentameric ligand-gated chloride ion channels that are activated by binding gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system (Sieghart 2006). Silexan, an essential ...
- However, this anti-apoptotic activity is expressed only when the cyclic pentameric structure of CRP is lost, resulting in formation of modified or monomeric CRP (mCRP), which may be formed in inflamed tissues. By Migration of ...
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