English Journal

Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation.

Capolicchio S1, Wang H, Thakor DT, Shears SB, Jessen HJ.
Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2014 Sep 1;53(36):9508-11. doi: 10.1002/anie.201404398. Epub 2014 Jul 14.
The ubiquitous mammalian signaling molecule bis-diphosphoinositol tetrakisphosphate (1,5-(PP)2 -myo-InsP4 , or InsP8 ) displays the most congested three-dimensional array of phosphate groups found in nature. The high charge density, the accumulation of unstable P-anhydrides and P-esters, the lack of
PMID 25044992

Arabidopsis inositol pentakisphosphate 2-kinase, AtIPK1, is required for growth and modulates phosphate homeostasis at the transcriptional level.

Kuo HF1, Chang TY, Chiang SF, Wang WD, Charng YY, Chiou TJ.
The Plant journal : for cell and molecular biology.Plant J.2014 Aug 23. doi: 10.1111/tpj.12650. [Epub ahead of print]
Inositol hexakisphosphate (IP6 ) provides a phosphorous reservoir in plant seeds; in addition, along with its biosynthesis intermediates and derivatives, IP6 also plays important roles in diverse developmental and physiological processes. Disruption of the Arabidopsis inositol pentakisphosphate 2-ki
PMID 25155524

Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio.

Wundenberg T, Grabinski N, Lin H, Mayr GW.
The Biochemical journal.Biochem J.2014 Aug 15;462(1):173-84. doi: 10.1042/BJ20130992.
InsP6 (inositol hexakisphosphate), the most abundant inositol phosphate in metazoa, is pyrophosphorylated to InsP7 [5PP-InsP5 (diphosphoinositol pentakisphosphate)] by cytosolic and nuclear IP6Ks (InsP6 kinases) and to 1PP-InsP5 by another InsP6/InsP7 kinase family. MINPP1 (multiple inositol-polypho
PMID 24865181

Japanese Journal

Myo-inositol Polyphosphate Intermediates in the Dephosphorylation of Phytic Acid by Acid Phosphatase with Phytase Activity from Rice Bran(Biological Chemistry)

HAYAKAWA Toshiro,SUZUKI Kayoko,MIURA Hidehiko,OHNO Takao,IGAUE Ikuo
Agricultural and Biological Chemistry 54(2), 279-286, 1990-02-23
… Hydrolysis of phytic acid proceeded via L-myo-inositol 1,2,3,4,5 and D-myo-inositol 1,2,4,5,6-pentakisphosphate, D-myo-inositol 1,2,5,6 and L-myo-inositol 1,2,3,4-tetrakisphosphate, D-myo-inositol 1,2,6 and myo-inositol 1,2,3-trisphosphate, D-myo-inositol 1,2-bisphosphate and finally myo-inositol monophosphate (myo-inositol 2,93%; …
NAID 110006324757