腫瘍随伴内分泌症候群
- 関
- ectopic hormone syndrome
WordNet
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
- of or belonging to endocrine glands or their secretions; "endocrine system" (同)endocrinal
PrepTutorEJDIC
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
- 内分泌(ぶんぴつ)の / 内分泌物;内分泌腺(せん)
UpToDate Contents
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English Journal
- Copeptin as a marker for arginine-vasopressin/antidiuretic hormone secretion in the diagnosis of paraneoplastic syndrome of inappropriate ADH secretion.
- Wuttke A, Dixit KC, Szinnai G, Werth SC, Haagen U, Christ-Crain M, Morgenthaler N, Brabant G.Author information Experimental and Clinical Endocrinology Med. Clinic I, University of Luebeck, Ratzeburger Allee 160D, 23538, Luebeck, Germany, anna.wuttke@gmx.de.AbstractDirect measurement of arginine-vasopressin/antidiuretic hormone (AVP/ADH) concentrations is not included in the standard diagnostic procedures for paraneoplastic syndrome of inappropriate ADH secretion (SIADH). Here, we evaluate the potential of copeptin measurement as a surrogate marker of AVP/ADH secretion for the direct diagnosis of suspected SIADH in cancer patients. Forty-six unselected cancer patients with serum sodium concentrations permanently below 135 mmol/L were included in this study. We compared standard diagnostic criteria for SIADH to the measurement of plasma copeptin in relation to osmolality. Normative data for comparison were constructed from 24 healthy controls studied under basal conditions, experimental dehydration, and hypotonic hypervolemia as well as from 222 hospital patients with no suspicion of an altered ADH regulation. Log transformation of copeptin revealed a linear relationship to plasma osmolality in the controls (R = 0.495, p < 0.001). Compared to these normative data, copeptin levels in most cancer patients were inappropriately high for plasma osmolality and were not significantly correlated. These results, suggestive for paraneoplastic SIADH, could be confirmed by conventional diagnostic procedures for SIADH. Current strategies to diagnose SIADH are difficult to perform under outpatients conditions. Our approach allows screening from a single plasma sample for true paraneoplastic ADH oversecretion and thus rapid selection for a specific therapy with an AVP receptor antagonist.
- Endocrine.Endocrine.2013 Dec;44(3):744-9. doi: 10.1007/s12020-013-9919-9. Epub 2013 Mar 12.
- Direct measurement of arginine-vasopressin/antidiuretic hormone (AVP/ADH) concentrations is not included in the standard diagnostic procedures for paraneoplastic syndrome of inappropriate ADH secretion (SIADH). Here, we evaluate the potential of copeptin measurement as a surrogate marker of AVP/ADH
- PMID 23479045
- Testicular choriocarcinoma presenting as hyperthyroidism.
- Heda P, Cushing G.
- The American journal of medicine.Am J Med.2013 Nov;126(11):e1-2. doi: 10.1016/j.amjmed.2013.07.017.
- PMID 24157290
- Neoplastic causes of abnormal puberty.
- Wendt S, Shelso J, Wright K, Furman W.Author information Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.AbstractBACKGROUND: Neoplasm-related precocious puberty (PP) is a rare presenting feature of childhood cancer. Moreover, evaluation of suspected PP in a child is complex, and cancer is often not considered. We characterized the clinicopathologic features of patients presenting with PP at a large pediatric cancer center, reviewed the relevant literature, and developed an algorithm for the diagnostic work-up of these patients.
- Pediatric blood & cancer.Pediatr Blood Cancer.2013 Oct 24. doi: 10.1002/pbc.24825. [Epub ahead of print]
- BACKGROUND: Neoplasm-related precocious puberty (PP) is a rare presenting feature of childhood cancer. Moreover, evaluation of suspected PP in a child is complex, and cancer is often not considered. We characterized the clinicopathologic features of patients presenting with PP at a large pediatric c
- PMID 24155044
Japanese Journal
- A Case Report of Paraneoplastic Neurological Syndrome Associated with Occult Breast Cancer
- KAWASOE Teru,YAMAMOTO Yutaka,OKUMURA Yasuhiro,IWASE Hirotaka
- Breast cancer : the journal of the Japanese Breast Cancer Society 13(2), 202-204, 2006-04-10
- NAID 10018167947
- A Case Report of Paraneoplastic Neurological Syndrome Associated with Occult Breast Cancer
- Kawasoe Teru,Yamamoto Yutaka,Okumura Yasuhiro,Iwase Hirotaka
- Breast Cancer 13(2), 202-204, 2006
- … Paraneoplastic syndromes are the rarest neurological complications in patients with breast cancer. … Here, we present a case of occult breast cancer presenting as paraneoplastic sensory neuropathy. … Although no paraneoplastic antibodies were found, paraneoplastic neurological syndrome was suspected after examination by the neurologist eliminated other possibilities. …
- NAID 130004467436
- Transforming growth factor-alpha (TGF α)-producing gastric carcinoma with acanthosis nigricans: An endocrine effect of TGF αin the pathogenesis of cutaneous paraneoplastic syndrome and epithelial hyperplasia of the esophagus.
- KOYAMA Shohei,IKEDA Kazuho,SATO Mikio,SHIBAHARA Ken,YUHARA Kyoko,FUKUTOMI Hisayuki,FUKUNAGA Kiyoshi,KANAZAWA Nobuo,YUZAWA Kenji,FUKAO Katashi,IIJIMA Tatsuo,KIKUCHI Masanori,TOMIYA Tomoaki,FUJIWARA Kenji
- Journal of gastroenterology 32(1), 71-77, 1997-02
- NAID 10007029056
Related Links
- paraneoplastic syndrome [par″ah-ne″o-plas´tik] a collective term for disorders arising from metabolic effects of cancer on tissues remote from the tumor; such disorders may, for example, appear as primary endocrine, hematologic, or ...
- Paraneoplastic Endocrine Syndrome 1. Paraneoplastic Endocrine Syndrome 2. Paraneoplastic Syndrome • Definition: a syndrome due to substances secreted by a tumour or its metastases, with effects occurring remotely ...
★リンクテーブル★
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- 英
- paraneoplastic endocrine syndrome, tumor-associated endocrine syndrome
- 関
- 異所性ホルモン症候群、異所性ホルモン産生腫瘍
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異所性ホルモン症候群
- 関
- paraneoplastic endocrine syndrome
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- 関
- endocrinic, endocrinal
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