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1. アテローム性腎血管性疾患に関係する慢性腎疾患 chronic kidney disease associated with atherosclerotic renovascular disease
2. 両側性アテローム性腎動脈狭窄症の治療 treatment of bilateral atherosclerotic renal artery stenosis
3. 片側性アテローム性腎動脈狭窄症の治療 treatment of unilateral atherosclerotic renal artery stenosis
4. 腎血管性高血圧の診断 establishing the diagnosis of renovascular hypertension
5. 腎血管性またはその他の原因による二次性高血圧の評価対象患者 who should be evaluated for renovascular or other causes of secondary hypertension

Reconstitution of signal transduction from the membrane to the nucleus in a baculovirus expression system: activation of Raf-1 leads to hypermodification of c-jun and c-fos via multiple pathways.

Agarwal S1, Corbley MJ, Roberts TM.
Oncogene.Oncogene.1995 Aug 3;11(3):427-38.
We have attempted to dissect signaling pathways involved in transmitting activating signals from the cell surface to the nucleus by reconstituting them in the baculovirus/Sf9 cell system. We have used this system to coexpress different combinations of the critical signaling proteins pp60v-src, p21v-
PMID 7543194

Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase.

Williams NG1, Paradis H, Agarwal S, Charest DL, Pelech SL, Roberts TM.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.1993 Jun 15;90(12):5772-6.
Mitogen-activated protein (MAP) kinases Raf-1, pp60src, and p21ras all play important roles in the transfer of signals from the cell surface to the nucleus. We have used the baculovirus/Sf9 insect cell system to elucidate the regulatory relationships between pp60v-src, p21v-ras, MAP kinase (p44erk1/
PMID 8390681

Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.

Lu X1, Chou TB, Williams NG, Roberts T, Perrimon N.
Genes & development.Genes Dev.1993 Apr;7(4):621-32.
Determination of cell fate at the posterior termini of the Drosophila embryo is specified by the activation of the torso (tor) receptor tyrosine kinase. This signaling pathway is mediated by the serine/threonine kinase D-raf and a protein tyrosine phosphatase corkscrew (csw). We found that expressio
PMID 8458578

Raf-l and p21^<v-ras> cooperate in the acti-vation of mitogen-activated protein kinase.