WordNet

a drug that induces labor by stimulating contractions of the muscles of the uterus (同)oxytocic drug

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/06 21:53:18」(JST)

wiki en

[Wiki en表示]

A uterotonic, also known as ecbolic, is an agent used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor, and to reduce postpartum hemorrhage.

Some uterotonics act as analogues of oxytocin. An oxytocinergic, or oxytocic, means "having to do with oxytocin (OXT)". The Oxytocin Receptor (OXTR) is the binding and activation site of oxytocin.

Some agents may act as indirect oxytocinergics:

5-HT_1A Receptor (5-HT_1AR): A protein responsible for inducing the secretion of oxytocin.
Serotonergic: A drug which acts upon serotonin and 5-HT_1AR, resulting in oxytocin release (e.g., MDMA ("Ecstasy").

Other uterotonics include Methylergonovine and Prostaglandin F2.

A tocolytic acts to oppose uterine contractility. These agents may be oxytocinergic in mechanism. For example, Atosiban works in this way.

References

This biology article is a stub. You can help Wikipedia by expanding it.

English Journal

Anti-inflammatory effects of ethanolic extract of Rosmarinus officinalis L. and rosmarinic acid in a rat model of neuropathic pain.

Ghasemzadeh Rahbardar M1, Amin B2, Mehri S3, Mirnajafi-Zadeh SJ4, Hosseinzadeh H5.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.Biomed Pharmacother.2017 Feb;86:441-449. doi: 10.1016/j.biopha.2016.12.049. Epub 2016 Dec 22.
BACKGROUND: Rosemary, Rosmarinus (R.) officinalis L. is a well-known plant with several useful properties such as analgesic, anti-inflammatory and anti-neurodegenerative. It has been used in folk medicine to alleviate rheumatic pain, stomachache and dysmenorrhea. Rosemary has several constituents su
PMID 28012923

Lipopolysaccharide reduces food passage rate from the crop by a prostaglandin-independent mechanism in chickens.

Tachibana T1, Ogino M1, Makino R1, Khan MS2, Cline MA3.
British poultry science.Br Poult Sci.2017 Feb;58(1):100-106. doi: 10.1080/00071668.2016.1237768. Epub 2016 Dec 2.
1. We examined the effect of lipopolysaccharide (LPS), a component of Gram-negative bacteria, on food passage in the digestive tract of chickens (Gallus gallus) in order to clarify whether bacterial infection affects food passage in birds. 2. Food passage in the crop was significantly reduced by int
PMID 27871194

Emergency obstetric and neonatal care availability, use, and quality: a cross-sectional study in the city of Lubumbashi, Democratic Republic of the Congo, 2011.

Ntambue AM1, Malonga FK2, Cowgill KD3, Dramaix-Wilmet M4, Donnen P4,5.
BMC pregnancy and childbirth.BMC Pregnancy Childbirth.2017 Jan 19;17(1):40. doi: 10.1186/s12884-017-1224-9.
BACKGROUND: While emergency obstetric and neonatal care (EmONC) is a proxy indicator for monitoring maternal and perinatal mortalities, in Democratic Republic of the Congo (DRC), data on this care is rarely available. In the city of Lubumbashi, the second largest in DRC with an estimated population
PMID 28103822

Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum.

BenSaad LA1, Kim KH2, Quah CC1, Kim WR3, Shahimi M4.
BMC complementary and alternative medicine.BMC Complement Altern Med.2017 Jan 14;17(1):47. doi: 10.1186/s12906-017-1555-0.
BACKGROUND: Punica granatum (pomegranate), an edible fruit originating in the Middle East, has been used as a traditional medicine for treatment of pain and inflammatory conditions such as peptic ulcer. The numerous risks associated with nonsteroidal anti-inflammatory drugs (NSAIDs) for treatment of
PMID 28088220

Japanese Journal

Carbetocin versus syntometrine in prevention of post-partum hemorrhage following vaginal delivery

NIRMALA Kampan,ZAINUDDIN Ani Amelia,GHANI Nur Azurah Abdul,ZULKIFLI Syed,ABDUL JAMIL Mohd
The journal of obstetrics and gynaecology research 35(1), 48-54, 2009-02-01
NAID 10025338446

Low-dose sublingual misoprostol versus methylergometrine for active management of the third stage of labor

CHHABRA Shakuntala,TICKOO Chandan
The journal of obstetrics and gynaecology research 34(5), 820-823, 2008-10-01
NAID 10022603491

(4)無茎性粘膜下子宮筋腫に対する子宮鏡下手術の工夫 : 一期的摘出法標準化の試み(講演要旨,<特集>第58回学術講演会シンポジウム-4「安全性の向上をめざした婦人科良性腫瘍に対する内視鏡手術」)

村上節
日本産科婦人科學會雜誌 58(12), 1818-1824, 2006-12-01
… In conclusion, the combination of techniques-the use of appropriate electrodes, the extruding the remnant myoma by the oxytocic agent-induced uterine contractions, and uncritical manipulations-will allow safe and certain hysteroresectoscopy of a sessile submucous myoma. …
NAID 110006204892

Effect of 2,5-Dimethylpyrazine on Uterine Contraction in Late Stage of Pregnant Female Rats(Pharmacology)

Yamada Kenji,Sano Miwa,Fujihara Hisato [他],OHTA Akihiro
Biological & pharmaceutical bulletin 26(11), 1614-1617, 2003-11-01
… Effect of 2,5-dimethylpyrazine (2,5-DMP) on oxytocic agent-induced late pregnant uterine contraction in female rats was studied. … Oxytocic agents induced-hypercontraction in the late phase of pregnant uterine movements were inhibited by administration of 2,5-DMP. …
NAID 110003608357