WordNet
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
- informal term for information; "give me the gen on your new line of computers"
PrepTutorEJDIC
- 遺伝子
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/01/19 13:35:15」(JST)
[Wiki en表示]
An overlapping gene is a gene whose expressible nucleotide sequence partially overlaps with the expressible nucleotide sequence of another gene.[1] In this way, a nucleotide sequence may make a contribution to the function of one or more gene products. The shared nucleotide sequence may be read in alternate reading frames during transcription of different genes, or (in double-stranded DNA), part of the antisense strand of one gene may form part of the sense strand of a different gene. They have been found in multiple domains of life, including bacteria, viruses and higher eukaryotes, including humans.[2]
References
- ^ Y. Fukuda, M. Tomita et T. Washio (1999). "Comparative study of overlapping genes in the genomes of Mycoplasma genitalium and Mycoplasma pneumoniae". Nucl. Acids Res. (Oxford Journals) 27 (8): 1847–1853. doi:10.1093/nar/27.8.1847.
- ^ C. Sanna, W. Li et L. Zhang (2008). "Overlapping genes in the human and mouse genomes". BMC Genomics 9 (169). doi:10.1186/1471-2164-9-169.
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Recombining Overlapping BACs into Single Large BACs.
- Kotzamanis G1, Kotsinas A.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2015;1227:123-39. doi: 10.1007/978-1-4939-1652-8_6.
- BAC clones containing the entire genomic region of a gene including the long-range regulatory elements are very useful for gene functional analysis. However, large genes often span more than the insert of a BAC clone, and single BACs covering the entire region of interest are not available. Here, we
- PMID 25239744
- Gammaretrovirus mRNA expression is mediated by a novel, bipartite post-transcriptional regulatory element.
- Pilkington GR1, Purzycka KJ2, Bear J1, Le Grice SF3, Felber BK4.
- Nucleic acids research.Nucleic Acids Res.2015 Jan 1;42(17):11092-106. doi: 10.1093/nar/gku798. Epub 2014 Sep 4.
- Post-transcriptional regulatory mechanisms of several complex and simple retroviruses and retroelements have been elucidated, with the exception of the gammaretrovirus family. We found that, similar to the other retroviruses, gag gene expression of MuLV and XMRV depends on post-transcriptional regul
- PMID 25190459
- Arabidopsis SEPALLATA proteins differ in cooperative DNA-binding during the formation of floral quartet-like complexes.
- Jetha K1, Theißen G1, Melzer R2.
- Nucleic acids research.Nucleic Acids Res.2015 Jan 1;42(17):10927-42. doi: 10.1093/nar/gku755. Epub 2014 Sep 2.
- The SEPALLATA (SEP) genes of Arabidopsis thaliana encode MADS-domain transcription factors that specify the identity of all floral organs. The four Arabidopsis SEP genes function in a largely yet not completely redundant manner. Here, we analysed interactions of the SEP proteins with DNA. All of the
- PMID 25183521
Japanese Journal
- 〈Original〉Generation and some characterization of BAC transgenic mouse that neurally expresses antisense RNA against the potential longevity determinant miR-29
- TANABE Hiroyuki,MATSUURA Yoshinori
- 近畿大学農学部紀要 46, 1-14, 2013-03
- … [Synopsis] miR-29, a gene family of microRNA, is highly expressed across the entire adulthood until life termination in the mouse central nervous system. … BAC (bacterial artificial chromosome)-mediated transgenesis is a powerful technology that facilitates spatial and temporal modulation of gene expression in vivo. …
- NAID 120005298690
- Zygosity Determination in Hairless Mice by PCR Based on Hrhr Gene Analysis
- Suzuki Osamu,Koura Minako,Noguchi Yoko,Uchio-Yamada Kozue,Matsuda Junichiro
- Experimental Animals 62(3), 267-273, 2013
- … We analyzed the Hr gene of a hairless mouse strain of unknown origin (HR strain, http://animal.nibio.go.jp/e_hr.html) to determine whether the strain shares a mutation with other hairless strains, such as HRS/J and Skh:HR-1, both of which have an Hrhr allele. … Using PCR with multiple pairs of primers designed to amplify multiple overlapping regions covering the entire Hr gene, we found an insertion mutation in intron 6 of mutant Hr genes in HR mice. …
- NAID 130003362963
- Antiproliferative, cell-cycle dysregulation effects of novel asiatic acid derivatives on human non-small cell lung cancer cells
- Wang Liang,Xu Jie,Zhao Chunhui,Zhao Longxuan,Feng Bin
- Chemical and Pharmaceutical Bulletin, 2013
- … To determine the cellular gene expression changes in A549 and PC9/G cells treated with A-3, Affymetrix GeneChip® Human Genome U133 Plus 2.0 Array were used to screen transcriptome differences. … Expression levels of 1121 genes in A549 and 1873 genes in PC9/G were significantly altered upon treatment with 10 μ M A-3 after 48 h, with 357 overlapping genes. …
- NAID 130003360908
Related Links
- ... such constraints can be alleviated by duplication of the overlapping gene pair, allowing for independent evolution of each gene in the resulting copies. This means that overlapping genes can thus only survive long evolutionary In 7 ...
- Background Overlapping genes are known to be common in viruses, mitochondria, bacteria, and plasmids [1], but are thought to be rare in eukaryotes. This view is changing because recent studies have suggested the ...
★リンクテーブル★
[★]
- 英
- [[]]
- 同
- overlapping gene
- 関
- [[]]
- 同
- overlapping gene
[★]
- 関
- overlap