WordNet

the source of somethings existence or from which it derives or is derived; "the rumor had its origin in idle gossip"; "vegetable origins"; "mineral origin"; "origin in sensation"
properties attributable to your ancestry; "he comes from good origins" (同)descent, extraction
an event that is a beginning; a first part or stage of subsequent events (同)origination, inception
the point of intersection of coordinate axes; where the values of the coordinates are all zero
(genetics) the process whereby DNA makes a copy of itself before cell division
the repetition of an experiment in order to test the validity of its conclusion; "scientists will not believe an experimental result until they have seen at least one replication"
(law) a pleading made by a plaintiff in reply to the defendants plea or answer
of or relating to a chromosome; "chromosomal defect"

PrepTutorEJDIC

〈U〉〈C〉(…の)『起源』発端;もと,原因《+『of』+『名』》 / 〈U〉『生まれ』,素性,血統 / 〈U〉〈C〉(数学で,座標の)原点
写し,複写,複製 / 《文》(被告の訴答に対する)原告の訴答
《選択を表し,語句・節を結んで》《肯定文・疑問文で》・・・『または』・・・,・・・か・・・ / 《否定文で》・・・も・・・もない / 《命令的表現の後で》『さもないと』 / 《前出の語を言い換えたり説明したりして》『すなわち』,言い換えれば

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Kono N1, Arakawa K2, Sato M2, Yoshikawa H3, Tomita M2, Itaya M4.
Journal of molecular biology.J Mol Biol.2014 Aug 12;426(16):2918-27. doi: 10.1016/j.jmb.2014.06.005. Epub 2014 Jun 16.
The oriC DNA replication origin in bacterial chromosomes, the location of which appears to be physically identified, is genetically regulated by relevant molecular machinery. In contrast, the location of the terminus remains obscure for many bacterial replicons, except for terC, the proposed and wel
PMID 24946150

Assembly of Helicobacter pylori initiation complex is determined by sequence-specific and topology-sensitive DnaA-oriC interactions.

Donczew R1, Mielke T2, Jaworski P3, Zakrzewska-Czerwińska J4, Zawilak-Pawlik A5.
Journal of molecular biology.J Mol Biol.2014 Jul 29;426(15):2769-82. doi: 10.1016/j.jmb.2014.05.018. Epub 2014 May 24.
In bacteria, chromosome replication is initiated by binding of the DnaA initiator protein to DnaA boxes located in the origin of chromosomal replication (oriC). This leads to DNA helix opening within the DNA-unwinding element. Helicobacter pylori oriC, the first bipartite origin identified in Gram-n
PMID 24862285

Beyond DnaA: the role of DNA topology and DNA methylation in bacterial replication initiation.

Donczew R1, Zakrzewska-Czerwińska J2, Zawilak-Pawlik A3.
Journal of molecular biology.J Mol Biol.2014 Jun 12;426(12):2269-82. doi: 10.1016/j.jmb.2014.04.009. Epub 2014 Apr 18.
The replication of chromosomal DNA is a fundamental event in the life cycle of every cell. The first step of replication, initiation, is controlled by multiple factors to ensure only one round of replication per cell cycle. The process of initiation has been described most thoroughly for bacteria, e
PMID 24747048

Absence of strand bias for deletion mutagenesis during chromosomal leading and lagging strand replication in Escherichia coli

Nagata Yuki,Kawaguchi Genta,Tago Yu-ichiro [他],IMAI Masaru,WATANABE Takashi,SAKURAI Shigehisa,IHARA Makoto,KAWATA Masakado,YAMAMOTO Kazuo
Genes & genetic systems 80(1), 1-8, 2005-02-01
… Investigations were carried out to determine whether both DNA strands involved in Escherichia coli chromosomal DNA replication are replicated with similar accuracy. … in pairs of polA deficient strains in which the chromosomal target gene tonB was oriented in the two possible directions relative to the origin of replication, oriC. …
NAID 130000062137

吉川寛
藥學雜誌 105(11), 1019-1028, 1985-11-25
… Recent progress in our studies on mechanism and regulation of initiation of chromosomal replication in Bacillus subtilis is reviewed. … The origin of the chromosomal replication, OriC, is supposed to be composed of deoxyribonucleic acid (DNA) signals for initiation of autonomous replication and its regulation. …
NAID 110003649559