オクトチアミン
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/30 09:57:57」(JST)
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Octotiamine
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| Systematic (IUPAC) name |
|
methyl 6-(acetylsulfanyl)-8-{[(2E)-2-{[(4-amino-2-methyl-5-pyrimidinyl)methyl](formyl)amino}-5-hydroxy-2-penten-3-yl]disulfanyl}octanoate
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| Identifiers |
| CAS Number |
137-86-0 |
| ATC code |
None |
| PubChem |
CID 3034020 |
| ChemSpider |
2298574 |
| Chemical data |
| Formula |
C23H36N4O5S3 |
| Molar mass |
544.751 g/mol |
SMILES
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Cc1ncc(c(n1)N)CN(C=O)/C(=C(\CCO)/SSCCC(CCCCC(=O)OC)SC(=O)C)/C
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InChI
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InChI=1S/C23H36N4O5S3/c1-16(27(15-29)14-19-13-25-17(2)26-23(19)24)21(9-11-28)35-33-12-10-20(34-18(3)30)7-5-6-8-22(31)32-4/h13,15,20,28H,5-12,14H2,1-4H3,(H2,24,25,26)/b21-16+
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Key:VJTXQHYNRDGLON-LTGZKZEYSA-N
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Octotiamine (INN, JAN; Gerostop, Neuvita, Neuvitan), also known as thioctothiamine, is an analogue of vitamin B1 which is used in Japan and Finland.[1][2]
See also
References
- ^ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1469–. ISBN 978-0-412-46630-4.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 756–. ISBN 978-3-88763-075-1.
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Vitamins (A11)
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|
| Fat soluble |
| A |
- α-Carotene
- β-Carotene
- Retinol#
- Tretinoin
|
|
| D |
- D2
- Ergosterol
- Ergocalciferol#
- D3
- 7-Dehydrocholesterol
- Previtamin D3
- Cholecalciferol
- 25-hydroxycholecalciferol
- Calcitriol (1,25-dihydroxycholecalciferol)
- Calcitroic acid
- D4
- D5
- D analogues
- Alfacalcidol
- Dihydrotachysterol
- Calcipotriol
- Tacalcitol
- Paricalcitol
|
|
| E |
- Tocopherol
- Tocotrienol
- Tocofersolan
|
|
| K |
- Naphthoquinone
- Phylloquinone (K1)
- Menaquinones (K2)
- Menadione (K3)‡
- Menadiol (K4)
|
|
|
| Water soluble |
| B |
- B1
- B1 analogues
- Acefurtiamine
- Allithiamine
- Benfotiamine
- Fursultiamine
- Octotiamine
- Prosultiamine
- Sulbutiamine
- B2
- B3
- B5
- Pantothenic acid
- Dexpanthenol
- Pantethine
- B6
- Pyridoxine#, Pyridoxal phosphate
- Pyridoxamine
- Pyritinol
- B7
- B9
- Folic acid
- Dihydrofolic acid
- Folinic acid
- Levomefolic acid
- B12
- Cyanocobalamin
- Hydroxocobalamin
- Methylcobalamin
- Cobamamide
- Choline
|
|
| C |
- Ascorbic acid#
- Dehydroascorbic acid
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|
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| Combinations |
|
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
English Journal
- Influence of powder characteristics of bulk substance with pharmaceutical processing.
- Tomozawa H, Momonaga M, Uemura T, Yazawa H.SourceManufacturing Technology Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan.
- Drug development and industrial pharmacy.Drug Dev Ind Pharm.1998 Sep;24(9):857-61.
- The physicochemical properties of crystals can vary with the crystallization procedure employed in their isolation and purification. Moreover, the success of any direct-tableting procedure is directly effected by the quality of the crystals used in this process. We examined the conventional crystall
- PMID 9876537
Japanese Journal
- 吉野 寿高,百永 眞士,篠崎 勝彦 [他],矢澤 久豊
- 化学工学論文集 23(6), 906-913, 1997-11-20
- … To develop such a complex, compound tablet, crystallization of Octotiamine was carried out and the crystallization method and conditions that produced the optimum tablet are established. …
- NAID 10002768466
Related Pictures
★リンクテーブル★
[★]
- 英
- octotiamine, octothiamine
- 商
- ノイビタ、ノイロビタン配合
- 関
- ビタミンB1