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WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- not structural
PrepTutorEJDIC
- 蛋白(たんばく)質
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/03/08 04:32:10」(JST)
[Wiki en表示]
In virology, a nonstructural protein is a protein encoded by a virus but it is not part of the viral particle.[1]
List
- NSP1 (rotavirus)
- NSP4 (rotavirus)
- NSP5 (rotavirus)
- Influenza non-structural protein
- NS1 influenza protein
References
- ^ Viral+Nonstructural+Proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
Viral proteins (early and late)
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DNA |
Herpes simplex
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Herpes simplex virus protein vmw65 · HHV capsid portal protein
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Hepatitis B
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HBsAg · HBcAg (HBeAg) · HBx · Hepatitis B virus DNA polymerase
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Epstein-Barr
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EBNA-1 · EBNA-2 · EBNA-3 · LMP-1 · LMP-2 · EBER
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RNA |
Rotavirus
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VNPs: NSP1 · NSP2 · NSP4 · NSP5 · NSP6
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Influenza
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capsid: matrix protein (M1 protein) · viral envelope (M2 protein)
glycoprotein: Influenza hemagglutinin · Neuraminidase
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Parainfluenza
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Parainfluenza hemagglutinin-neuraminidase
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Mumps
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Mumps hemagglutinin-neuraminidase
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Measles
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Measles hemagglutinin
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RSV
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Respiratory syncytial virus G protein
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Hepatitis C
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VSPs: E1 · E2
VNPs: P7 · NS2 · NS3 · NS4 · NS5
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RT |
Structure and genome of HIV
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VSPs: gag · pol (Integrase, Reverse transcriptase, HIV-1 protease) · env (gp120, gp41)
VRAPs: transactivators (Tat, Rev, Vpr) · Nef · Vif · Vpu
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Fusion protein |
Gag-onc fusion protein
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cutn/syst (hppv/hiva, infl/zost/zoon)/epon
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drug (dnaa, rnaa, rtva, vacc)
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UpToDate Contents
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English Journal
- The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity.
- Hartjen P, Höchst B, Heim D, von der Kammer H, Lucke J, Reinholz M, Baier A, Smeets R, Wege H, Borowski P, Schulze Zur Wiesch J.SourceDepartment of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359, Hamburg, Germany, philip.hartjen@gmail.com.
- Cellular & molecular biology letters.Cell Mol Biol Lett.2013 Sep;18(3):447-58. doi: 10.2478/s11658-013-0099-7. Epub 2013 Jul 27.
- Helicase motif VI is a short arginine-rich motif within the NTPase/helicase domain of the non-structural protein 3 (NS3) of the hepatitis C virus (HCV). We previously demonstrated that it reduces the catalytic activity and intracellular shuttling of protein kinase C (PKC). Thus, NS3-mediated PKC inh
- PMID 23893289
- Rotavirus NSP1 Mediates Degradation of Interferon Regulatory Factors through Targeting of the Dimerization Domain.
- Arnold MM, Barro M, Patton JT.SourceRotavirus Molecular Biology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
- Journal of virology.J Virol.2013 Sep;87(17):9813-21. doi: 10.1128/JVI.01146-13. Epub 2013 Jul 3.
- Rotavirus nonstructural protein NSP1 can inhibit expression of interferon (IFN) and IFN-stimulated gene products by inducing proteasome-mediated degradation of IFN-regulatory factors (IRFs), including IRF3, IRF5, and IRF7. All IRF proteins share an N-terminal DNA-binding domain (DBD), and IRF3, IRF5
- PMID 23824805
- Measles Virus Nonstructural C Protein Modulates Viral RNA Polymerase Activity by Interacting with Host Protein SHCBP1.
- Ito M, Iwasaki M, Takeda M, Nakamura T, Yanagi Y, Ohno S.SourceDepartment of Virology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
- Journal of virology.J Virol.2013 Sep;87(17):9633-42. doi: 10.1128/JVI.00714-13. Epub 2013 Jun 26.
- Most viruses possess strategies to circumvent host immune responses. The measles virus (MV) nonstructural C protein suppresses the interferon response, thereby allowing efficient viral growth, but its detailed mechanism has been unknown. We identified Shc Src homology 2 domain-binding protein 1 (SHC
- PMID 23804634
Japanese Journal
- Key role of regulated upon activation normal T-cell expressed and secreted, nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8 (A/H1N1) infection in A549 bronchial epithelial cells
- Phung Thuy Thi Bich,Sugamata Ryuichi,Uno Kazuko [他]
- Microbiology and immunology 55(12), 874-884, 2011-12
- NAID 40019163634
- C型肝炎ウイルスNS5A蛋白とToll-like receptorシグナル伝達経路を介したApoptosisの抑制 (特集 肝炎ウィルスによる病態形成,治療抵抗性獲得のメカニズム)
- Nonstructural protein 1 antibody-based epitope-blocking enzyme-linked immunosorbent assay to differentiate Japanese encephalitis virus from dengue virus infections in humans
- Konisi Eiji,Konishi Mayu
- Japanese Journal of Infectious Diseases 64(4), 284-291, 2011-07
- NAID 40018924976
Related Links
- 1. Hepatology. 2012 Mar;55(3):742-8. doi: 10.1002/hep.24724. Epub 2012 Jan 30. Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus ...
- 1. Viral Immunol. 2013 Feb;26(1):75-83. doi: 10.1089/vim.2012.0061. Nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA Vaccine. Bao H ...
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★リンクテーブル★
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- nonstructural protein
- 関
- 非構造タンパク質
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- nonstructural protein, NS
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- virus NS protein
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- nonstructurally