非ケトン性アシドーシス
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- ケトアシドーシス
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- 1. 成人における低カリウム血症の臨床症状および治療clinical manifestations and treatment of hypokalemia in adults [show details]
… two main examples are insulin therapy in diabetic ketoacidosis or nonketotic hyperglycemia, and bicarbonate therapy in metabolic acidosis with a normal anion gap. Potassium repletion is most easily accomplished …
- 2. 特定の脂肪酸酸化障害specific fatty acid oxidation disorders [show details]
…later-onset form. The severe neonatal form can present with metabolic crisis, including metabolic acidosis, nonketotic hypoglycemia, and hyperammonemia; additional features include hypotonia, cardiomyopathy, hepatomegaly …
- 3. 乳酸アシドーシスの原因causes of lactic acidosis [show details]
… form of chronic lactic acidosis can occur in the absence of sepsis or hypoperfusion (type B lactic acidosis). Intravenous (IV) epinephrine is associated with a lactic acidosis . The mechanism likely …
- 4. 成人における代謝性アシドーシスへのアプローチapproach to the adult with metabolic acidosis [show details]
… metabolic acidosis will be reviewed here. An overview of simple and mixed acid-base disorders and the approach in children with metabolic acidosis are discussed separately. Metabolic acidosis is defined …
- 5. 代謝性アシドーシスを有する小児に対するアプローチapproach to the child with metabolic acidosis [show details]
… that result in metabolic acidosis. An approach to the physiology, diagnosis, and treatment of metabolic acidosis in children will be reviewed in this topic. Metabolic acidosis in adults is discussed separately …
English Journal
- Unidentified anion gap metabolic acidosis.
- Langman LJ, Jannetto PJ, Sztajnkrycer MD.
- Clinical biochemistry. 2019 Mar;65()53-54.
- A 35-month-old female with nonketotic hyperglycinemia (NKH) presented to the Emergency department with severe hypoglycemia, fever, and several episodes of seizures. Due to worsening respiratory status, additional seizures and anion gap worsening metabolic acidosis the patient was transferred to the
- PMID 30578759
- Acid-base and electrolyte disturbances in patients with diabetes mellitus.
- Pipeleers L, Wissing KM, Hilbrands R.
- Acta clinica Belgica. 2019 Feb;74(1)28-33.
- PMID 30470164
- Glycine decarboxylase deficiency-induced motor dysfunction in zebrafish is rescued by counterbalancing glycine synaptic level.
- Riché R, Liao M, Pena IA, Leung KY, Lepage N, Greene N, Sarafoglou K, Schimmenti LA, Drapeau P, Samarut É.
- JCI insight. 2018 11;3(21).
- Glycine encephalopathy (GE), or nonketotic hyperglycinemia (NKH), is a rare recessive genetic disease caused by defective glycine cleavage and characterized by increased accumulation of glycine in all tissues. Here, based on new case reports of GLDC loss-of-function mutations in GE patients, we aime
- PMID 30385710
Japanese Journal
- α-グルコシダーゼ阻害剤による気腹症を伴う腸管囊胞状気腫症の1例
- 山本 昌明,小川 雅生,奥村 哲,豊田 翔,水村 直人,今川 敦夫,出村 公一,川崎 誠康,亀山 雅男
- 日本腹部救急医学会雑誌 35(1), 141-145, 2015
- 症例は86歳の女性で糖尿病に対してα-グルコシダーゼ阻害剤（以下，α-GI）の投与を受けていた。意識障害を主訴に前医へ搬送され，腹部CTで消化管穿孔を疑われ当院に救急搬送となった。JCS-200，腹部は膨満で軟，腹膜刺激症状は意識障害により不明であった。血液・尿検査などから，高浸透圧性非ケトン性昏睡の状態であり，腹部CTで腹腔内遊離ガスを認めたことから消化管穿孔の疑いで試験開腹術を施行した。開腹し …
- NAID 130005069708
- ミオグロビン尿症，各種すい酵素，ＣＡ１９‐９の上昇がみられた高浸透圧性非ケトン性糖尿病性昏睡の１例
- 影山 洋,野口 雅秀,山内 浩
- 医療 47(9), 705-709, 1993
- ミオグロビン尿症と各種膵酵素, CA19-9の上昇がみられた高浸透圧性非ケトン性糖尿病性昏睡(HKNC)の1例を報告する. 症例は52歳男性で主訴は意識障害, 入院約3カ月前より口渇・多尿・体重減少あり, 1週間前より感冒症状あり, 意識障害が出現したために入院. 入院時著明な高血糖, 高浸透圧血症があったがケトアシドーシスはみられなかった. CPK, ミオグロビンの著しい上昇と腎機能障害があり, …
- NAID 130004107435
- 骨格筋融解における急性腎不全 自験６例の臨床的検討:―自験6例の臨床的検討―
- 飯塚 正,小山 哲夫,小林 正貴,大場 正二,菊池 博,大越 教夫,成田 光陽,東條 静夫
- 日本腎臓学会誌 34(3), 317-324, 1992
- … The causes of rhabdomyolysis were as follows : one crush syndrome, one acute arterial occlusion, one diabetic hyperosmolar nonketotic coma and three cases of malignat syndrome due to neuroleptica (mainly haloperidol). … In patients with myoglobinuric ARF, severse metabolic acidosis and hypocalcemia in the oligulic phase and hypercalcemia in the diuretic phase were prominant. …
- NAID 130004169914
Related Links
- Hyperglycemic Hyperosmolar Nonketotic State (HONK) is a clinical picture occurring in Type II diabetes, characterized by hyperglycemia, hyperosmolarity (> 350 mOsm/L), and marked. HONK is often precipitated by the same 6 I's ...
- Diabetic ketoacidosis and Hyperglycemic Hyperosmolar Nonketotic Syndrome Diabetic Ketoacidosis: Affects mainly Type 1 diabetics Ketonesand Acidosis present Hyperglycemia presents >300 mg/dL Variableosmolality Happens ...
- INTRODUCTION Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS, also known as hyperosmotic hyperglycemic nonketotic state [HHNK]) are two of the most serious acute complications of diabetes. They are ...
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