ニコチン性アセチルコリン受容体, nAChR
WordNet
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- releasing or activated by acetylcholine or a related compound
PrepTutorEJDIC
- =sense organ / 受信装置
UpToDate Contents
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- 1. ニコチンの心血管系への影響cardiovascular effects of nicotine [show details]
…dose. Nicotine is a ganglionic and central nervous system stimulant, the actions of which are mediated via nicotinic cholinergic receptors. Nicotine binds to nicotinic cholinergic receptors that are …
- 2. COPDにおけるムスカリン受容体拮抗薬治療の役割role of muscarinic antagonist therapy in copd [show details]
…mediated through nicotinic and muscarinic cholinergic receptors. The figure outlines the role of nicotinic and muscarinic receptors in cholinergic transmission in the airway Nicotinic receptors are located …
- 3. 手術室外での小児への迅速導入気管挿管（RSI）：鎮静薬と筋弛緩薬rapid sequence intubation rsi outside of the operating room in children medications for sedation and paralysis [show details]
…nondepolarizing paralytic agent that induces muscle paralysis by competitive antagonism at the nicotinic cholinergic receptor. At a dose of 1 mg/kg, it has a rapid onset of effect (30 to 60 seconds, IV), but a duration …
- 4. エストロゲンと認知機能estrogen and cognitive function [show details]
…by stimulating choline acetyltransferase activity and raises the concentration of hypothalamic nicotinic acetylcholine receptors. The glutamate system, a second neurotransmitter system involved in learning…
- 5. 有機リン剤およびカルバメート中毒organophosphate and carbamate poisoning [show details]
…ganglia and end organs of the parasympathetic nervous system are regulated by nicotinic and muscarinic cholinergic receptor subtypes, respectively The dominant clinical features of acute cholinergic toxicity …
English Journal
- Glucose attenuates impairments in memory and CREB activation produced by an α4β2 but not an α7 nicotinic receptor antagonist.
- Morris KA, Li S, Bui DD, Gold PE.SourceNeuroscience Program, College of Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, United States.
- Neuropharmacology.Neuropharmacology.2013 Apr;67:233-42. doi: 10.1016/j.neuropharm.2012.11.008. Epub 2012 Nov 16.
- Glucose improves memory for a variety of tasks when administered to rats and mice near the time of training. Prior work indicates glucose may enhance memory by increasing the synthesis and release of the neurotransmitter acetylcholine in the brain. To investigate if specific acetylcholine receptor s
- PMID 23164619
- γ-Aminobutyric acid type a receptor inhibition triggers a nicotinic neuroprotective mechanism.
- Ferchmin PA, Pérez D, Castro Alvarez W, Penzo MA, Maldonado HM, Eterovic VA.SourceSchool of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico. ferchmin@gmail.com.
- Journal of neuroscience research.J Neurosci Res.2013 Mar;91(3):416-25. doi: 10.1002/jnr.23155. Epub 2012 Dec 26.
- Nicotinic acetylcholine receptor (nAChR)-mediated neuroprotection has been implicated in the treatment of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases and hypoxic ischemic events as well as other diseases hallmarked by excitotoxic and apoptotic neuronal death. Several mod
- PMID 23280428
- Inhibition of Cholinergic Signaling Causes Apoptosis in Human Bronchioalveolar Carcinoma.
- Lau JK, Brown KC, Thornhill BA, Crabtree CM, Dom AM, Witte TR, Hardman WE, McNees CA, Stover CA, Carpenter AB, Luo H, Chen YC, Shiflett BS, Dasgupta P.SourceAuthors' Affiliations: Departments of Pharmacology, Physiology, and Toxicology, Biochemistry and Microbiology, and Anatomy and Pathology, Joan C. Edwards School of Medicine, Marshall University, Huntington; and Department of Biology, Alderson-Broaddus College, Philippi, West Virginia.
- Cancer research.Cancer Res.2013 Feb 7. [Epub ahead of print]
- Recent case-controlled clinical studies show that bronchioalveolar carcinomas (BAC) are correlated with smoking. Nicotine, the addictive component of cigarettes, accelerates cell proliferation through nicotinic acetylcholine receptors (nAChR). In this study, we show that human BACs produce acetylcho
- PMID 23222296
Japanese Journal
- Ketamine-Induced Prefrontal Serotonin Release Is Mediated by Cholinergic Neurons in the Pedunculopontine Tegmental Nucleus
- The international journal of neuropsychopharmacology 21(3), 305-310, 2018-03
- NAID 120006469165
- Nicotinic Acetylcholine Receptors Mediate the Suppressive Effect of an Injection of Diluted Bee Venom into the GV3 Acupoint on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats
Related Links
- The figure below shows the two main families of acetylcholine receptors: muscarinic and nicotinic. In structural terms, muscarinic receptors are G-coupled protein receptors, while nicotinic receptors are ligand-gated ion channels ...
- Acetylcholine Receptors Two Types of Receptors There are two types of acetylcholine receptors (AChR) that bind acetylcholine and transmit its signal: muscarinic AChRs and nicotinic AChRs, which are named after the agonists ...
★リンクテーブル★
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- 関
- nicotine、nicotine sulfate
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