- 関
- NK-2 receptor
WordNet
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- =sense organ / 受信装置
UpToDate Contents
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English Journal
- Behavioural and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant.
- Tamburella A, Leggio GM, Micale V, Navarria A, Bucolo C, Cicirata V, Drago F, Salomone S.SourceDepartment of Clinical and Molecular Biomedicine, Section of Pharmacology and Biochemistry, Catania University, Catania, Italy.
- The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP).Int J Neuropsychopharmacol.2013 May;16(4):813-23. doi: 10.1017/S1461145712000612. Epub 2012 Jun 14.
- These experiments were undertaken to assess the mechanisms underlying the antidepressant-like effects of the neurokinin-2 (NK(2)) receptor antagonist saredutant (SR48968) in rats tested in the forced swim test (FST), by analysing hippocampal brain-derived neurotrophic factor (BDNF) and plasma cortic
- PMID 22695046
- Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists.
- Misu R, Noguchi T, Ohno H, Oishi S, Fujii N.SourceGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
- Bioorganic & medicinal chemistry.Bioorg Med Chem.2013 Apr 15;21(8):2413-7. doi: 10.1016/j.bmc.2013.01.036. Epub 2013 Feb 1.
- Neurokinin B (NKB) is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R). NKB with the consensus sequence of the tachykinin peptide family also binds to other tachykinin receptors [neurokinin-1 receptor (NK1R) and neu
- PMID 23473945
- Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats.
- Brancati SB, Zádori ZS, Németh J, Gyires K.SourceDepartment of Pharmaceutical Sciences - Pharmacology Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
- Brain research bulletin.Brain Res Bull.2013 Feb;91:38-45. doi: 10.1016/j.brainresbull.2013.01.004. Epub 2013 Jan 14.
- The aim of the present study was to analyze the potential role of substance P (SP) in gastric mucosal defense and to clarify the receptors and mechanisms that may be involved in it. Gastric ulceration was induced by oral administration of acidified ethanol in male Wistar rats. Mucosal levels of calc
- PMID 23328537
Japanese Journal
- Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists.
- Misu Ryosuke,Noguchi Taro,Ohno Hiroaki,Oishi Shinya,Fujii Nobutaka
- Bioorganic & medicinal chemistry 21(8), 2413-2417, 2013-04-15
- … Neurokinin B (NKB) is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R). …
- NAID 120005244454
- モルモットの過換気誘発気道収縮モデルにおけるタキキニンの関与
- 津田 香織,馬島 徹,伊藤 玲子,服部 知洋,赤柴 恒人
- 日大医学雑誌 67(6), 339-345, 2008
- … 容体拮抗薬は喘息患者の気道収縮を減弱する.本研究では,モルモットの過換気誘発気道収縮 (HIB) モデルを人工換気下に過換気負荷をして,タキキニン受容体拮抗薬の選択的 NK1 受容体拮抗薬 (FK 888) と NK1 + NK2 受容体拮抗薬 (FK224) を投与し,肺抵抗,気管支肺胞洗浄液中のメディエーター・細胞分画を測定した.その結果,過換気負荷群は負荷 5 分後に肺抵抗が上昇し,FK224 投与群のみ投与濃度依存性に肺抵抗が減少 …
- NAID 130004548757
- Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage
Related Links
- potent antagonist of the neurokinin-2 receptor Daniela Fattori Menarini Ricerche, Rome, Italy J Med Chem 53:4148-65. 2010.... 64 ...
- 1. J Immunol. 2012 May 1;188(9):4200-8. doi: 10.4049/jimmunol.1102521. Epub 2012 Apr 2. Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor. Kitamura H, Kobayashi M ...
Related Pictures
★リンクテーブル★
[★]
- 英
- neurokinin-2 receptor、NK-2 receptor
- 関
- ニューロキニン-2受容体、ニューロキニン-2レセプター、ニューロキニン2レセプター、NK-2受容体、NK-2レセプター
[★]
- 英
- neurokinin-2 receptor
- 関
- ニューロキニン2受容体、ニューロキニン-2受容体、ニューロキニン-2レセプター
[★]
- 英
- neurokinin-2 receptor
- 関
- ニューロキニン2受容体、ニューロキニン-2受容体、ニューロキニン2レセプター
[★]
- 関
- neurokinin-2 receptor