神経芽細胞腫
WordNet
- malignant tumor containing embryonic nerve cells; usually metastasizes quickly
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English Journal
- Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y CELLS.
- Ngok-Ngam P, Watcharasit P, Thiantanawat A, Satayavivad J.SourceChulabhorn Graduate Institute, 54 Kamphaeng Phet 6 Road, Lak Si, Bangkok, 10210, Thailand.
- Cellular & molecular biology letters.Cell Mol Biol Lett.2013 Mar;18(1):58-74. doi: 10.2478/s11658-012-0039-y. Epub 2012 Nov 16.
- Glycogen synthase kinase-3 (GSK3) and p53 play crucial roles in the mitochondrial apoptotic pathway and are known to interact in the nucleus. However, it is not known if GSK3 has a regulatory role in the mitochondrial translocation of p53 that participates in apoptotic signaling following DNA damage
- PMID 23161404
- Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
- Ando K, Dourlen P, Sambo AV, Bretteville A, Bélarbi K, Vingtdeux V, Eddarkaoui S, Drobecq H, Ghestem A, Bégard S, Demey-Thomas E, Melnyk P, Smet C, Lippens G, Maurage CA, Caillet-Boudin ML, Verdier Y, Vinh J, Landrieu I, Galas MC, Blum D, Hamdane M, Sergeant N, Buée L.SourceInserm, UMR 837, Alzheimer & Tauopathies, Jean-Pierre Aubert Research Centre, Faculty of Medicine, Institute of Predictive Medicine and Therapeutic Research, Lille, France; Univ. Lille Nord de France, UDSL, Lille, France.
- Neurobiology of aging.Neurobiol Aging.2013 Mar;34(3):757-69. doi: 10.1016/j.neurobiolaging.2012.08.004. Epub 2012 Aug 25.
- A prerequisite to dephosphorylation at Ser-Pro or Thr-Pro motifs is the isomerization of the imidic peptide bond preceding the proline. The peptidyl-prolyl cis/trans isomerase named Pin1 catalyzes this mechanism. Through isomerization, Pin1 regulates the function of a growing number of targets inclu
- PMID 22926167
- Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes.
- Troiber C, Edinger D, Kos P, Schreiner L, Kläger R, Herrmann A, Wagner E.SourceDepartment of Pharmacy, Pharmaceutical Biotechnology, Center for System-based Drug Research and Center for NanoScience (CeNS), Ludwig-Maximilians-University, Butenandtstrasse 5-13, 81377 Munich, Germany.
- Biomaterials.Biomaterials.2013 Feb;34(5):1624-33. doi: 10.1016/j.biomaterials.2012.11.021. Epub 2012 Nov 28.
- Nine sequence-defined, polycationic oligomers were synthesized containing motifs of three consecutive tyrosines (Y3) as stabilizing components for pDNA and siRNA polyplex assembly. For pDNA, a combination of terminal oligotyrosines and cysteines was necessary and sufficient for stable polyplex forma
- PMID 23199743
Japanese Journal
- Implications of surgical intervention in the treatment of neuroblastomas : 20-year experience of a single institution
- TAJIRI Tatsuro,SOUZAKI Ryota,KINOSHITA Yoshiaki,KOGA Yuhki,SUMINOE Aiko,HARA Toshiro,TAGUCHI Tomoaki
- Surgery today : the Japanese journal of surgery 42(3), 220-224, 2012-03-01
- NAID 10030231044
- Clinical study of olfactory neuroblastomas
- 前田 明輝,原口 正大,梅野 博仁,千年 俊一,三橋 拓之,中島 格
- 頭頸部外科 22(2), 141-147, 2012
- A clinical study was performed on 13 patients with olfactory neuroblastoma who were treated between 1984 and 2011 at the Department of Otolaryngology-Head and Neck Surgery, Kurume University School of …
- NAID 130002136986
- 山下 真治,上原 久生,新甫 武也,横上 聖貴,盛口 清香,佐藤 勇一郎,丸塚 浩助,福島 剛,竹島 秀雄
- 脳神経外科ジャーナル 20(11), 833-840, 2011-11-20
- まれな原発性トルコ鞍部神経芽腫を経験したので報告する.症例は75歳,女性.当初偶然に発見されたトルコ鞍部腫瘍であり,無症候性であるため経過観察されていた.2年後,視力視野障害が出現し,傍鞍部に伸展する腫瘍の拡大が認められた.神経内視鏡を用いたTSSに加え,放射線照射,白金製剤を用いた化学療法にて腫瘍縮小効果を得た.原発性トルコ鞍部神経芽腫は,これまでに9例の報告しか存在しない非常にまれな腫瘍である …
- NAID 110008762365
Related Links
- Neuroblastoma is an embryonal neoplasm that is predominantly a disease of early childhood. It is the most common extracranial, solid neoplasm and is responsible... ... Epidemiology Fewer than 100 children are diagnosed with ...
- Treating Pediatric Cancers Posted on July 31, 2012 by admin Here is a link to an article about the surprising success of using Crizotinib to treat three pediatric cancers (anaplastic large cell lymphoma(ALCL), inflammatory ...
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神経芽細胞腫 NB neuroblastomas