UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. アルツハイマー病の疫学、病理、および病因 epidemiology pathology and pathogenesis of alzheimer disease
2. プリオンによる中枢神経系疾患 diseases of the central nervous system caused by prions
3. 味覚および嗅覚障害の解剖学および病因 anatomy and etiology of taste and smell disorders
4. 認知症の予防 prevention of dementia
5. アルツハイマー病の遺伝学 genetics of alzheimer disease

English Journal

Deterministic control of mean alignment and elongation of neuron-like cells by grating geometry: a computational approach.

Sergi PN1, Marino A, Ciofani G.
Integrative biology : quantitative biosciences from nano to macro.Integr Biol (Camb).2015 Oct 5;7(10):1242-1252.
Neuron-like cells are driven by their surrounding environment through local topography. A causal mechanotransductive web of topography-force relationships influences and controls complex cellular phenomena such as growth and alignment. This work aimed to provide a computational framework able to mod
PMID 26114801

Effect of Genetic Polymorphisms (SNPs) in CHRNA7 Gene on Response to Acetylcholinesterase Inhibitors (AChEI) in Patients with Alzheimer's Disease.

Russo P1, Kisialiou A, Moroni R, Prinzi G, Fini M.
Current drug targets.Curr Drug Targets.2015 Oct 1. [Epub ahead of print]
Cholinergic transmission loss is one of the major features in Alzheimer's Disease (AD). Acetylcholinesterase inhibitors (AChEI) are moderately active in AD. 7nAChR (nicotinic acetylcholine receptor), encoded by CHRNA7, is involved in cholinergic neurotransmission and AD pathogenesis. 7nAChR is
PMID 26424395

Li A1, Ceballos-Diaz C1, DiNunno N1, Levites Y1, Cruz PE1, Lewis J1, Golde TE2, Chakrabarty P2.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.FASEB J.2015 Oct;29(10):4384-98. doi: 10.1096/fj.15-275834. Epub 2015 Jul 8.
Inflammatory activation precedes and correlates with accumulating τ lesions in Alzheimer's disease and tauopathies. However, the relationship between neuroinflammation and etiology of pathologic τ remains elusive. To evaluate whether inflammatory signaling may promote or accelerate neurofibrillary
PMID 26156074

Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons

吉村教
弘前医療福祉大学紀要 2(1), 1-14, 2011-03-30
… The resultsshowed that neurons were classi›ed into 3 types: neuron types with NFT-rich, NFT-rare, and NFT-free.As to the pathogenesis of AD brain lesions, it is known that Aβ deposition occurs first and theoligomers with the highest toxicity develop into proto›brils and ›brils and ›nally form neuritic plaqueswhich contain degenerated neurites. …
NAID 40019065546

高野憲一,井野口友紀,倉地道雄
薬学雑誌 131(4), 581-586, 2011
… In this study, we investigated the effects of ethanol extracts of herbal medicines on neuritic outgrowth induced by NGF. … Four herbal extracts (Geranium thunbergii, Humulus lupulus, Rosmarinus officinalis and Salvia officinalis L.) inhibited NGF-induced neuritic outgrowth in PC12 cells. …
NAID 130000678839

リンク元	「neurite」「神経突起」
拡張検索	「polyneuritic hereditary spinocerebellar ataxia」「polyneuritic hereditary spinocerebellarat axia」