ネチコナゾール
- 関
- neticonazole hydrochloride
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/17 21:55:40」(JST)
[Wiki en表示]
Neticonazole
|
Systematic (IUPAC) name |
1-{(E)-2-(Methylthio)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Identifiers |
ATC code
|
None |
PubChem |
CID: 5282433 |
ChemSpider |
4445587 N |
UNII |
KVL61ZF9UO Y |
Chemical data |
Formula |
C17H22N2OS |
Molecular mass
|
302.43 g/mol |
SMILES
- CCCCCOc1ccccc1/C(=C\SC)/n2ccnc2
|
InChI
-
InChI=1S/C17H22N2OS/c1-3-4-7-12-20-17-9-6-5-8-15(17)16(13-21-2)19-11-10-18-14-19/h5-6,8-11,13-14H,3-4,7,12H2,1-2H3/b16-13+ N
Key:VWOIKFDZQQLJBJ-DTQAZKPQSA-N N
|
N (what is this?) (verify) |
Neticonazole (INN) is an imidazole antifungal for the treatment of fungal skin infections.[1][2]
Neticonazole is only approved for use in Japan. It is sold as a topical ointment under the tradename Atolant.
References
- ^ Nimura K, Niwano Y, Ishiduka S, Fukumoto R (August 2001). "Comparison of in vitro antifungal activities of topical antimycotics launched in 1990s in Japan". Int. J. Antimicrob. Agents 18 (2): 173–8. doi:10.1016/S0924-8579(01)00365-X. PMID 11516941.
- ^ Tsuboi R, Matsumoto T, Ogawa H (May 1996). "Hyperkeratotic chronic tinea pedis treated with neticonazole cream. Neticonazole Study Group". Int. J. Dermatol. 35 (5): 371–3. doi:10.1111/j.1365-4362.1996.tb03644.x. PMID 8734665.
Antifungals (D01 and J02)
|
|
Wall/
membrane |
Ergosterol
inhibitors |
Azoles
(lanosterol 14
alpha-demethylase inhibitors) |
Imidazoles |
- Topical: bifonazole
- butoconazole
- chlormidazole
- clotrimazole#
- croconazole
- econazole
- fenticonazole
- ketoconazole
- isoconazole
- miconazole#
- neticonazole
- omoconazole
- oxiconazole
- sertaconazole
- sulconazole
- tioconazole
|
|
Triazoles |
- Topical: (fluconazole#, fosfluconazole
- terconazole)
- Systemic: (fluconazole
- hexaconazole
- isavuconazole
- itraconazole
- posaconazole
- voriconazole)
|
|
Thiazoles |
|
|
|
Polyene antimycotics
(ergosterol binding) |
- Topical: (hamycin
- natamycin
- nystatin#)
Systemic: (amphotericin B#, hamycin)
|
|
Allylamines
(squalene monooxygenase
inhibitors) |
- Topical: (amorolfine
- butenafine
- naftifine
- terbinafine)
Systemic: terbinafine
|
|
|
β-glucan synthase
inhibitors |
- echinocandins (anidulafungin
- caspofungin
- micafungin)
|
|
|
Intracellular |
Pyrimidine analogues/
thymidylate synthase inhibitors |
|
|
Mitotic inhibitors |
|
|
Aminoacyl tRNA synthetase inhibitors |
|
|
|
Others |
- bromochlorosalicylanilide
- methylrosaniline
- tribromometacresol
- undecylenic acid
- polynoxylin
- chlorophetanol
- chlorphenesin
- ticlatone
- sulbentine
- ethylparaben
- haloprogin
- salicylic acid
- selenium disulfide#
- ciclopirox
- amorolfine
- dimazole
- tolnaftate
- tolciclate
- sodium thiosulfate#
- Whitfield's ointment#
- potassium iodide#
- taurolidine
- tea tree oil
- citronella oil
- lemon grass
- orange oil
- patchouli
- lemon myrtle
- PCP: pentamidine
- dapsone
- atovaquone
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of fungal disease
|
|
Description |
|
|
Disease |
|
|
Treatment |
|
|
|
English Journal
- Expression of epidermal growth factor receptor in canine osteosarcoma: association with clinicopathological parameters and prognosis.
- Selvarajah GT1, Verheije MH, Kik M, Slob A, Rottier PJ, Mol JA, Kirpensteijn J.
- Veterinary journal (London, England : 1997).Vet J.2012 Aug;193(2):412-9. doi: 10.1016/j.tvjl.2012.02.009. Epub 2012 Mar 19.
- Expression of epidermal growth factor receptor (EGFR) is associated with aggressive growth and metastasis of a range of tumours, including osteosarcomas (OS), although some studies have reported no relevance to clinicopathological events or prognosis. The present study evaluated EGFR mRNA and protei
- PMID 22436430
- In vitro antifungal activities of luliconazole, a new topical imidazole.
- Koga H1, Nanjoh Y, Makimura K, Tsuboi R.
- Medical mycology.Med Mycol.2009;47(6):640-7. doi: 10.1080/13693780802541518.
- Luliconazole is a topical antifungal drug newly developed in Japan. The present study compares the in vitro antifungal activity of luliconazole against clinically important dermatomycotic fungi with that of other representative antifungal drugs. The reference drugs chosen were five classes of nine t
- PMID 19115136
- [Guidelines for diagnosis and treatment of mucocutaneous candidiasis].
- Katoh T1.
- Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology.Nihon Ishinkin Gakkai Zasshi.2009;50(4):207-12.
- This document summarizes current knowledge about diagnosis and treatment of candidiasis affecting the skin and oral mucosa. Several clinical forms of mucocutaneous candidiasis are distinguished depending on a patient's age and infected site, e.g. Candida intertrigo, erythema mycoticum infantile, ero
- PMID 19942790
Japanese Journal
- 日本医真菌学会雑誌 = Japanese journal of medical mycology 50(4), 207-212, 2009-10-30
- NAID 10026094530
- 各種外用抗真菌薬の in vitro 抗真菌活性の測定
- Effects of Antifungal Drugs on Proliferation Signals in Candida albicans(Microbiology)
Related Links
- ネチコナゾール塩酸塩(Neticonazole hydrochloride)の検索ならお薬検索QLife(キューライフ)。お医者さんが処方する処方薬と、薬局で買える市販薬(OTC)、の効果と副作用、写真、添付文書、保管方法等を掲載。商品名だけでなく一般名や ...
- 抗真菌剤アトラント軟膏 (製薬会社:久光製薬株式会社)アトラントクリーム (製薬会社:久光製薬株式会社)白癬菌やカンジダ菌などの真菌の細胞膜に作用し、完全発育阻止と殺菌作用を示します。 通常、水虫、皮膚のカンジダ症 ...
Related Pictures
★リンクテーブル★
[★]
- 英
- neticonazole
- 化
- 塩酸ネチコナゾール neticonazole hydrochloride
- 商
- アトラント
[★]
- 関
- neticonazole