WordNet
- easily agitated; "a nervous addict"; "a nervous thoroughbred"
- of or relating to the nervous system; "nervous disease"; "neural disorder" (同)neural
- the transmission of heat or electricity or sound (同)conductivity
PrepTutorEJDIC
- 『神経の』 / 『神経質な』,神経過敏な / 『心配な』,不安な
- (熱・電気の)伝導;(液体を)管などで導くこと
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- 1. 神経伝導検査：応答遅延 nerve conduction studies late responses
- 2. 神経伝導検査の概要 overview of nerve conduction studies
- 3. 血液透析における水質の維持 maintaining water quality for hemodialysis
- 4. 自動血液分析装置 automated hematology instrumentation
- 5. 熱傷の分類 classification of burns
English Journal
- Myelin architecture: zippering membranes tightly together.
- Bakhti M1, Aggarwal S, Simons M.Author information 1Max-Planck-Institute of Experimental Medicine, Hermann-Rein-Str. 3, Göttingen, Germany, mostafa.bakhti@helmholtz-muenchen.de.AbstractRapid nerve conduction requires the coating of axons by a tightly packed multilayered myelin membrane. In the central nervous system, myelin is formed from cellular processes that extend from oligodendrocytes and wrap in a spiral fashion around an axon, resulting in the close apposition of adjacent myelin membrane bilayers. In this review, we discuss the physical principles underlying the zippering of the plasma membrane of oligodendrocytes at the cytoplasmic and extracellular leaflet. We propose that the interaction of the myelin basic protein with the cytoplasmic leaflet of the myelin bilayer triggers its polymerization into a fibrous network that drives membrane zippering and protein extrusion. In contrast, the adhesion of the extracellular surfaces of myelin requires the down-regulation of repulsive components of the glycocalyx, in order to uncover weak and unspecific attractive forces that bring the extracellular surfaces into close contact. Unveiling the mechanisms of myelin membrane assembly at the cytoplasmic and extracelluar sites may help to understand how the myelin bilayers are disrupted and destabilized in the different demyelinating diseases.
- Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2014 Apr;71(7):1265-77. doi: 10.1007/s00018-013-1492-0. Epub 2013 Oct 29.
- Rapid nerve conduction requires the coating of axons by a tightly packed multilayered myelin membrane. In the central nervous system, myelin is formed from cellular processes that extend from oligodendrocytes and wrap in a spiral fashion around an axon, resulting in the close apposition of adjacent
- PMID 24165921
- Paranodal dysmyelination in peripheral nerves of Trembler mice.
- Rosenbluth J1, Bobrowski-Khoury N.Author information 1Department of Neuroscience and Physiology, NYU School of Medicine, New York, New York.AbstractSubtle defects in paranodes of myelinated nerve fibers can cause significant physiological malfunction. We have investigated myelinated fibers in the peripheral nervous system (PNS) of the Trembler mouse, a model of CMT-1A neuropathy, for evidence of such defects. Ultrastructural analysis shows that the "transverse bands," which attach the myelin sheath to the axon at the paranodal axoglial junction, are grossly diminished in number in Trembler nerve fibers. Although paranodes often appear to be greatly elongated, it is only a short region immediately adjacent to the node of Ranvier that displays transverse bands. Where transverse bands are missing, the junctional gap widens, thus reducing resistance to short circuiting of nodal action currents during saltatory conduction and increasing the likelihood that axonal K(+) channels under the myelin sheath will be activated. In addition, we find evidence that structural domains in Trembler axons are incompletely differentiated, consistent with diminution in nodal Na channel density, which could further compromise conduction. Deficiency of transverse bands may also increase susceptibility to disruption of the paranodal junction and retraction of the myelin sheath. We conclude that Trembler PNS myelinated fibers display subtle defects in paranodal and nodal regions that could contribute significantly to conduction defects and increased risk of myelin detachment. © 2014 Wiley Periodicals, Inc.
- Journal of neuroscience research.J Neurosci Res.2014 Apr;92(4):476-85. doi: 10.1002/jnr.23326. Epub 2014 Jan 21.
- Subtle defects in paranodes of myelinated nerve fibers can cause significant physiological malfunction. We have investigated myelinated fibers in the peripheral nervous system (PNS) of the Trembler mouse, a model of CMT-1A neuropathy, for evidence of such defects. Ultrastructural analysis shows that
- PMID 24446165
- T-type channels in the sino-atrial and atrioventricular pacemaker mechanism.
- Mesirca P1, Torrente AG, Mangoni ME.Author information 1Département de Physiologie, Institut de Génomique Fonctionnelle, LabEx ICST, 34094, Montpellier, France.AbstractCardiac automaticity is a fundamental physiological function in vertebrates. Heart rate is under the control of several neurotransmitters and hormones and is permanently adjusted by the autonomic nervous system to match the physiological demand of the organism. Several classes of ion channels and proteins involved in intracellular Ca(2+) handling contribute to pacemaker activity. Voltage-dependent T-type Ca(2+) channels are an integral part of the complex mechanism underlying pacemaking. T-type channels also contribute to impulse conduction in mice and humans. Strikingly, T-type channel isoforms are co-expressed in the cardiac conduction system with other ion channels that play a major role in pacemaking such as f- (HCN4) and L-type Cav1.3 channels. Pharmacologic inhibition of T-type channels reduces the spontaneous activity of isolated pacemaker myocytes of the sino-atrial node, the dominant heart rhythmogenic centre. Target inactivation of T-type Cav3.1 channels abolishes I Ca,T in both sino-atrial and atrioventricular myocytes and reduces the daily heart rate of freely moving mice. Cav3.1 channels contribute also to automaticity of the atrioventricular node and to ventricular escape rhythms, thereby stressing the importance of these channels in automaticity of the whole cardiac conduction system. Accordingly, loss-of-function of Cav3.1 channels contributes to severe form of congenital bradycardia and atrioventricular block in paediatric patients.
- Pflügers Archiv : European journal of physiology.Pflugers Arch.2014 Apr;466(4):791-9. doi: 10.1007/s00424-014-1482-6. Epub 2014 Feb 27.
- Cardiac automaticity is a fundamental physiological function in vertebrates. Heart rate is under the control of several neurotransmitters and hormones and is permanently adjusted by the autonomic nervous system to match the physiological demand of the organism. Several classes of ion channels and pr
- PMID 24573175
Japanese Journal
- Selective Sinoatrial Node Optical Mapping and the Mechanism of Sinus Rate Acceleration
- SHINOHARA Tetsuji,PARK Hyung-Wook,JOUNG Boyoung,MARUYAMA Mitsunori,CHUA Su-Kiat,HAN Seongwook,SHEN Mark J.,CHEN Peng-Sheng,LIN Shien-Fong
- Circulation journal : official journal of the Japanese Circulation Society 76(2), 309-316, 2012-01-25
- … We conclude that, in the isolated canine RA, a high extracellular potassium concentration can suppress atrial excitability thus leading to SAN-RA conduction block, allowing selective optical mapping of the intact SAN. …
- NAID 10030035379
- 多チャンネル表面筋電図による非侵襲的神経-筋系活動計測法
- 中村 英夫,岩崎 孝紘,小西 有人 [他],吉田 正樹
- 電子情報通信学会技術研究報告. MBE, MEとバイオサイバネティックス 109(460), 79-82, 2010-03-02
- 本研究の目的は,多チャンネル表面筋電図から運動単位から発生する活動電位を同定し,神経系活動を反映する運動単位発火頻度と筋組織の電気的・化学的特性を反映する活動電位伝導速度の同時計測を行うための計測法を開発することである.運動単位発火時刻を同定し,発火頻度を算出し中枢神経系活動を評価する.また,同定した発火時刻をトリガとして切り出した筋電図チャンネル間の時間遅れから伝導速度を推定する.伝導速度から末 …
- NAID 110008000918
- ＜Poster＞Modulation of neuronal activities by interactions between neurons and glial cells
- Yamazaki Yoshihiko,Hozumi Yasukazu,Kaneko Kenya [他],Fujiwara Hiroki,Kato Hiroshi,Fujii Satoshi
- 弘前醫學 61(Supplement), S174-S180, 2010-00-00
- … Action potentials are the fundamental signals for relaying information from one region to another inthe nervous system. … Weinvestigated the modulatory eff ects of glial cells on the fi ring pattern and the axonal conduction of action potentialsusing rat hippocampal slice preparation. …
- NAID 110007617198
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- Organized group of cells specialized for the conduction of electrochemical stimuli from sensory receptors through a network to the site at which a response occurs. All living organisms are able to detect...
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★リンクテーブル★
| リンク元 | 「神経伝導」「nerve conduction」 |
| 関連記事 | 「nervous」「conduction」 |
「神経伝導」
「nerve conduction」
「nervous」
- adj.
- 神経の、心配な、神経質な
- 関
- anxiety、anxious、anxiously、care、concern、fear、nerve、nervi、nervousness、nervus、neural、neuro、neuron、neuroticism、trouble、uneasy、worrisome、worry
「conduction」
- n.
- 関
- conduct