WordNet

of long duration; not new; "old tradition"; "old house"; "old wine"; "old country"; "old friendships"; "old money"
past times (especially in the phrase `in days of old'
skilled through long experience; "an old offender"; "the older soldiers" (同)older
(used especially of persons) having lived for a relatively long time or attained a specific age; "his mother is very old"; "a ripe old age"; "how old are you?"
(used for emphasis) very familiar; "good old boy"; "same old story"

PrepTutorEJDIC

『年とった』,老齢の / 『年上の』,年長の / 『ある年月』(『年齢』)『の』,…歳の / (物事が)『古い』,古くさい,新しくない / 《名詞の前にのみ用いて》『昔なじみの』,昔なつかしい / 《名詞の前にのみ用いて》『古代の』,大昔の / 《名詞の前にのみ用いて》(現在に対して)以前の,もとの / (衣服など)使い古した / (人が)経験のある,老練な / 《話》《呼び掛けで親しみなどをこめて》 / 《話》《名詞の前にのみ用い,前の形容詞を強めて》非常な,すばらしい / 昔

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Novel naphthochalcone derivative accelerate dermal wound healing through induction of epithelial-mesenchymal transition of keratinocyte.

Seo GY1, Ho MT1, Bui NT1, Kim YM1, Koh D2, Lim Y3, Hyun C4, Cho M5,6.
Journal of biomedical science.J Biomed Sci.2015 Jul 1;22(1):47. doi: 10.1186/s12929-015-0141-3.
BACKGROUND: Wound healing is an intricate process whereby the skin repairs itself after injury. The epithelial-mesenchymal transition (EMT) is associated with wound healing and tissue regeneration. Naphthochalcone derivatives have various pharmaceutical properties. We investigated the effect of a no
PMID 26130135

Selective fluorescence sensing of Cu(II) and Zn(II) using a simple Schiff base ligand: naked eye detection and elucidation of photoinduced electron transfer (PET) mechanism.

Ganguly A1, Ghosh S1, Kar S1, Guchhait N2.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2015 May 15;143:72-80. doi: 10.1016/j.saa.2015.02.013. Epub 2015 Feb 12.
A simple Schiff base compound 2-((cyclohexylmethylimino)-methyl)-naphthalen-1-ol (2CMIMN1O) has been synthesized and characterized by (1)H NMR, (13)C NMR and FT-IR spectroscopic techniques. A significantly low emission yield of the compound has been rationalized in anticipation with photo-induced el
PMID 25721777

Effective targeting of proton transfer at ground and excited states of ortho-(2'-imidazolyl)naphthol constitutional isomers.

Oliveira TC1, Carmo LF, Murta B, Duarte LG, Nome RA, Rocha WR, Brandão TA.
Physical chemistry chemical physics : PCCP.Phys Chem Chem Phys.2015 Jan 28;17(4):2404-15. doi: 10.1039/c4cp04337e. Epub 2014 Dec 9.
Steady-state and time-resolved spectroscopy and quantum chemical computational studies were employed to investigate ground and excited state proton transfer of a novel series of ortho-(1H-imidazol-2-yl)naphthol constitutional isomers: 1-(1H-imidazol-2-yl)naphthalen-2-ol (1NI2OH), 2-(1H-imidazol-2-yl
PMID 25490412

Identification of Saccharomyces cerevisiae Tub1 a-Tubulin as a Potential Target for NKH-7, a Cytotoxic 1-Naphthol Derivative Compound

Chanklan Ruthada,Mizunuma Masaki,Kongkathip Ngampong [他],HASITAPAN Komkrit,KONGKATHIP Boonsong,MIYAKAWA Tokichi
Bioscience, biotechnology, and biochemistry 72(4), 1023-1031, 2008-04-23
… on <I>zds1</I>Δ strain yeast, we found 2-((1-(hydroxymethyl) cyclohexyl) methyl) naphthalen-1-ol (NKH-7) to be an active compound. … By gene cloning, a <I>TUB1</I> …
NAID 10027526664