nabumetone

ナブメトン

 

WordNet

  1. a nonsteroidal anti-inflammatory drug (trade name Relafen) (同)Relafen

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/22 11:28:11」(JST)

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English Journal

  • Synthesis and antidiabetic performance of β-amino ketone containing nabumetone moiety.
  • Wang H, Yan JF, Song XL, Fan L, Xu J, Zhou GM, Jiang L, Yang DC.SourceSchool of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
  • Bioorganic & medicinal chemistry.Bioorg Med Chem.2012 Mar 15;20(6):2119-30. Epub 2012 Feb 2.
  • We wish to report the further design and improved synthesis that resulted in two series of target molecules, TM-1 and TM-2, with remarkably simplified structures containing β-amino ketone of discrete nabumetone moiety. These were obtained via a 'one-pot, two-step, three-component' protocol of Manni
  • PMID 22364952
  • Toxicology of frequently encountered nonsteroidal anti-inflammatory drugs in dogs and cats.
  • Khan SA, McLean MK.SourceASPCA Animal Poison Control Center, 1717 South Philo Road, Suite 36, Urbana, IL 61802, USA. safdar.khan@aspca.org
  • The Veterinary clinics of North America. Small animal practice.Vet Clin North Am Small Anim Pract.2012 Mar;42(2):289-306, vi-vii.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) are a group of heterogeneous compounds extensively used in both human and veterinary medicine for their antipyretic, anti-inflammation, and analgesic properties. NSAIDs consist of a wide range of pharmacologically active agents with different chemical st
  • PMID 22381180

Japanese Journal

  • In Vitro Characterization of the Cytochrome P450 Isoforms Involved in the Metabolism of 6-Methoxy-2-napthylacetic Acid, an Active Metabolite of the Prodrug Nabumetone
  • Matsumoto Kaori,Nemoto Eiichi,Hasegawa Tetsuya,Akimoto Masayuki,Sugibayashi Kenji
  • Biological & Pharmaceutical Bulletin 34(5), 734-739, 2011
  • … The cytochrome P450 (CYP) isoforms that catalyze the oxidation metabolism of 6-methoxy-2-napthylacetic acid (6-MNA), an active metabolite of nabumetone, were studied in rats and humans. …
  • NAID 130000657788
  • アルブミンサイト2結合阻害薬である6-メトキシー2-ナフチル酢酸によるフチルビプロフェンの蛋白結合阻害に関する基礎的検討
  • 徳永 仁,高村 徳人,緒方 賢次,吉田 裕樹,瀬戸口 奈央,近藤 照義,西尾 豊隆,川井 恵一
  • 九州保健福祉大学研究紀要 11, 153-158, 2010-03
  • 非ステロイド性抗炎症薬(NSAID)フルルビプロフェン(FP)の蛋白結合率は約99%であり、組織移行性が低い。6-メトキシ-2-ナフチル酢酸(6MNA)は、NSAIDの1つであるナブメトンの活性代謝産物である。これらの薬物は、ともにヒト血清アルブミン(HSA)のサイトIIに強く結合する。私たちは、LLC-PK1を用いて6MNA添加時のFPの細胞膜透過性について調べた。この実験では、細胞膜プレートの …
  • NAID 110007577972

Related Links

Nabumetone is a non-steroidal anti-inflammatory drug (NSAID), the only 1- naphthaleneacetic acid derivative. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex and ...
Learn about the prescription medication Relafen (Nabumetone), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling.


Related Pictures

Nabumetone 750mg Tablets - Generic RelafenNabumetone Oral Tablet 500Mg Drug NABUMETONE (NABUMETONE)DailyMed - NABUMETONE- nabumetone tablet Label: NABUMETONE- nabumetone tablet, film Nabumetone Oral Tablet Drug Information



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