ムターゼ
- 関
- intramolecular transferase
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/02/06 08:38:54」(JST)
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Not to be confused with dismutase.
A mutase is an enzyme of the isomerase class that catalyzes the shifting of a functional group from one position to another within the same molecule. Examples of this are bisphosphoglycerate mutase, which appears in red blood cells and phosphoglycerate mutase, which acts in glycolysis. In glycolysis, it changes 3-phosphoglycerate to 2-phosphoglycerate. In particular it moves phosphate groups within a single molecule, for instance: phosphoglycerate mutase.
See also
- Phosphoglucomutase
- Methylmalonyl-CoA mutase
- Wikipedia:MeSH_D08#MeSH_D08.811.399.520_---_intramolecular_transferases_.28EC_5.4.29
Proteins: enzymes
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Activity |
- Active site
- Binding site
- Catalytic triad
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
- Enzyme kinetics
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
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Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
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Classification |
- Enzyme superfamily
- EC number
- List of enzymes
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Types |
- EC1 Oxidoreductases(list)
- EC2 Transferases(list)
- EC3 Hydrolases(list)
- EC4 Lyases(list)
- EC5 Isomerases(list)
- EC6 Ligases(list)
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- B
- enzm
- 1.1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 10
- 11
- 13
- 14
- 15-18
- 2.1
- 3.1
- 4.1
- 5.1
- 6.1-3
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Isomerase: mutases (EC 5.4)
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5.4.1 Acyl Groups |
- Lysolecithin acylmutase
- Precorrin-8X methylmutase
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5.4.2 Phosphomutases |
- Phosphoglycerate mutase
- Bisphosphoglycerate mutase
- Phosphoglucomutase
- Phosphomannomutase
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5.4.99 Other groups |
- Methylmalonyl-CoA mutase
- Lanosterol synthase
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- B
- enzm
- 1.1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 10
- 11
- 13
- 14
- 15-18
- 2.1
- 3.1
- 4.1
- 5.1
- 6.1-3
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UpToDate Contents
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English Journal
- Proteome basis for intramuscular variation in color stability of beef semimembranosus.
- Nair MN1, Suman SP2, Chatli MK3, Li S1, Joseph P4, Beach CM5, Rentfrow G1.
- Meat science.Meat Sci.2016 Mar;113:9-16. doi: 10.1016/j.meatsci.2015.11.003. Epub 2015 Nov 3.
- The objective of the present study was to characterize the proteome basis for intramuscular color stability variations in beef semimembranosus. Semimembranosus muscles from eight carcasses (n=8) were fabricated into 2.54-cm thick color-labile inside (ISM) and color-stable outside (OSM) steaks. One s
- PMID 26588815
- In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction.
- Mehra-Chaudhary R1, Dai Y2, Sobrado P2, Tanner JJ3.
- Biochemistry.Biochemistry.2016 Feb 16;55(6):833-6. doi: 10.1021/acs.biochem.6b00035. Epub 2016 Feb 4.
- UDP-galactopyranose mutase (UGM) plays an essential role in galactofuranose biosynthesis in pathogens by catalyzing the conversion of UDP-galactopyranose to UDP-galactofuranose. Here we report the first crystal structure of a covalent intermediate in the UGM reaction. The 2.3 Å resolution structure
- PMID 26836146
- Identification of B. anthracis N(5)-carboxyaminoimidazole ribonucleotide mutase (PurE) active site binding compounds via fragment library screening.
- Lei H1, Jones C1, Zhu T1, Patel K1, Wolf NM2, Fung LW2, Lee H3, Johnson ME4.
- Bioorganic & medicinal chemistry.Bioorg Med Chem.2016 Feb 15;24(4):596-605. doi: 10.1016/j.bmc.2015.12.029. Epub 2015 Dec 18.
- The de novo purine biosynthesis pathway is an attractive target for antibacterial drug design, and PurE from this pathway has been identified to be crucial for Bacillus anthracis survival in serum. In this study we adopted a fragment-based hit discovery approach, using three screening methods-satura
- PMID 26740153
Japanese Journal
- 植物細胞壁多糖の生合成ならびに構造解析に関する研究(受賞論文)
- Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2.
- Purification and Characterization of UDP-Arabinopyranose Mutase from Chlamydomonas reinhardtii
- Bioscience, biotechnology, and biochemistry 77(9), 1874-1878, 2013-09-23
- NAID 10031202737
Related Links
- Definition of MUTASE: any of various enzymes that catalyze molecular rearrangements and especially those involving the transfer of phosphate from one hydroxyl group to another in the same molecule Take a 3 minute break! Play ...
- mutase mu·tase (myōō'tās, -tāz) n. Any enzyme that catalyzes the rearrangement of atoms within a molecule, especially one that causes the transfer of a phosphate group from one carbon atom to another.
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