WordNet

make ones way by force; "He muscled his way into the office"
animal tissue consisting predominantly of contractile cells (同)muscular_tissue
one of the contractile organs of the body (同)musculus
authority or power or force (especially when used in a coercive way); "the senators used their muscle to get the party leader to resign"
examination of tissues or liquids from the living body to determine the existence or cause of a disease

PrepTutorEJDIC

〈U〉(動物体の組織としての)『筋肉』,筋(きん);〈C〉(体の各部を動かす)筋肉 / 〈U〉力,(特に)筋力,腕力 / 《俗に》(…に)強引に割り込む《+『in on』(『into, through』)+『名』》
筋肉の,筋力のある / 力ずくの

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/25 22:31:46」(JST)

wiki en

In medicine, a muscle biopsy is a procedure in which a piece of muscle tissue is removed from an organism and examined microscopically. A muscle biopsy can lead to the discovery of problems with a nervous system, connective tissue, vascular system, or musculoskeletal system.

Indications

In humans with weakness and low muscle tone, a muscle biopsy can help distinguish between myopathies (where the pathology is in the muscle tissue itself) and neuropathies (where the pathology is at the nerves innervating those muscles). Muscle biopsies can also help to distinguish among various types of myopathies, by microscopic analysis for differing characteristics when exposed to a variety of chemical reactions and stains.

However, in some cases the muscle biopsy alone is inadequate to distinguish between certain myopathies. For example, a muscle biopsy showing the nucleus pathologically located in the center of the muscle cell would indicate "centronuclear myopathy", but research has shown that a variety of myopathies can cause these centronuclear biopsy appearance, and hence the specific genetic testing becomes increasingly important.^[1]^[2] Additionally muscle biopsy is the only certain way to clarify ones muscle fiber types. I.e. by undergoing a muscle biopsy one can get a clear picture of which type of muscles dominates his/her body.

Procedure

A biopsy needle is usually inserted into a muscle, wherein a small amount of tissue remains. Alternatively, an "open biopsy" can be performed by obtaining the muscle tissue through a small surgical incision.

References

^ Pierson CR, Tomczak K, Agrawal P, Moghadaszadeh B, Beggs AH (July 2005). "X-linked myotubular and centronuclear myopathies". J. Neuropathol. Exp. Neurol. 64 (7): 555–64. doi:10.1097/01.jnen.0000171653.17213.2e. PMID 16042307.
^ Bitoun M, Maugenre S, Jeannet PY et al. (November 2005). "Mutations in dynamin 2 cause dominant centronuclear myopathy". Nat. Genet. 37 (11): 1207–9. doi:10.1038/ng1657. PMID 16227997.

External links

Muscle Biopsy MedlinePlus
Muscle Biopsy: Overview Therapath Pathology

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 筋力低下患者へのアプローチ approach to the patient with muscle weakness
2. 成人における皮膚筋炎および多発性筋炎の診断および鑑別診断 diagnosis and differential diagnosis of dermatomyositis and polymyositis in adults
3. 末梢神経疾患および筋疾患の鑑別診断 differential diagnosis of peripheral nerve and muscle disease
4. 代謝性ミオパチーへのアプローチ approach to the metabolic myopathies
5. ミトコンドリアミオパシー：臨床的特徴および診断 mitochondrial myopathies clinical features and diagnosis

English Journal

Mesenchymal stem cell injection ameliorates chronic renal failure in a rat model.

Villanueva S, Ewertz E, Carrion F, Tapia A, Vergara C, Cespedes C, Saez PJ, Luz P, Irarrazabal C, Carreno JE, Figueroa F, Vio CP.Source*Laboratory of Integrative and Molecular Physiology, Los Andes University, Santiago, Chile.
Clinical science (London, England : 1979).Clin Sci (Lond).2011 Dec 1;121(11):489-99.
CKD (chronic kidney disease) has become a public health problem. The therapeutic approaches have been able to reduce proteinuria, but have not been successful in limiting disease progression. In this setting, cell therapies associated with regenerative effects are attracting increasing interest. We
PMID 21675962

Ghrelin reduces rat myocardial calcification induced by nicotine and vitamin D3 in vivo.

Wang F, Jiang T, Tang C, Su Z, Zhang N, Li G.SourceDepartment of Pathology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
International journal of molecular medicine.Int J Mol Med.2011 Oct;28(4):513-9. doi: 10.3892/ijmm.2011.710. Epub 2011 May 23.
Ghrelin, a newly discovered bioactive peptide, initially was identified as a strong stimulant for the release of growth hormone (GH) and that has improved cardiac function in patients suffering from end-stage chronic heart failure. Increasing evidence has demonstrated that ghrelin may have myocardia
PMID 21617846

Japanese Journal

多発性筋炎を合併した自己免疫性肝炎の1例

林学,阿部和道,斉藤理恵,佐藤秀三,物江恭子,菅野有紀子,斎藤広信,岩館治代,高橋敦史,大平弘正
肝臓 52(6), 344-350, 2011
症例は72歳女性．これまで健診では異常を指摘されたことがなく，ここ数年間は受診していなかった．2009年9月頃から骨粗鬆症のため近医へ通院していたが，同年12月の血液検査にて肝障害を指摘され精査目的に紹介となった．抗核抗体陽性とIgG高値，肝生検組織にてinterface hepatitisとロゼット形成を認め自己免疫性肝炎（AIH）と診断された．また，下肢筋力低下と筋原性酵素の上昇が認められ，筋 …
NAID 130000880382

特異的なCT像を呈した直腸癌穿通による骨盤内膿瘍の1例

金澤周,塩澤学,田村周三,稲垣大輔,山本直人,大島貴,湯川寛夫,利野靖,今田敏夫,赤池信
日本大腸肛門病学会雑誌 64(2), 88-92, 2011
症例は54歳女性．主訴は血便．下部消化管内視鏡検査で肛門縁から8cmの部位に全周性狭窄をともなう2型病変を認め，生検で高分化型腺癌の診断であった．注腸造影検査では上部直腸から直腸S状部にかけて全周性の狭窄像を認めたが，腸管外への造影剤の流出は認めなかった．CTでは仙骨前面から両側梨状筋に至る広範な骨盤内膿瘍形成を認め，直腸癌の腸間膜側への穿通による骨盤内膿瘍の診断でHartmann手術およびドレナ …
NAID 130000428450

Related Pictures

★リンクテーブル★

「muscle」

Muscle biopsy
	Intervention
	Micrograph of a muscle biopsy showing ragged red fibers, a finding seen in various types of mitochondrial diseases. Gomori trichrome stain.
ICD-9:	15.01

　　[★]

n.

筋肉

[1] Pierson CR, Tomczak K, Agrawal P, Moghadaszadeh B, Beggs AH (July 2005). "X-linked myotubular and centronuclear myopathies". J. Neuropathol. Exp. Neurol. 64 (7): 555–64. doi:10.1097/01.jnen.0000171653.17213.2e. PMID 16042307.

[2] Bitoun M, Maugenre S, Jeannet PY et al. (November 2005). "Mutations in dynamin 2 cause dominant centronuclear myopathy". Nat. Genet. 37 (11): 1207–9. doi:10.1038/ng1657. PMID 16227997.

匿名

検索

案内

案内

muscle biopsy