WordNet

involving or depending on several factors or causes (especially pertaining to a condition or disease resulting from the interaction of many genes)

English Journal

The ABCG5/8 cholesterol transporter and myocardial infarction versus gallstone disease.

Stender S1, Frikke-Schmidt R2, Nordestgaard BG3, Tybjærg-Hansen A4.Author information 1Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.2Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; The Copenhagen General Population Study, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.3The Copenhagen General Population Study, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.4Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; The Copenhagen General Population Study, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospitals and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address: anne.tybjaerg.hansen@regionh.dk.AbstractOBJECTIVE: To test the hypothesis that genetic variation in ABCG5/8, the transporter responsible for intestinal and hepatobiliary cholesterol efflux, might simultaneously influence plasma and biliary cholesterol levels, and hence risk of myocardial infarction(MI) and gallstone disease in opposite directions.
Journal of the American College of Cardiology.J Am Coll Cardiol.2014 Mar 5. pii: S0735-1097(14)01393-X. doi: 10.1016/j.jacc.2013.12.055. [Epub ahead of print]
OBJECTIVE: To test the hypothesis that genetic variation in ABCG5/8, the transporter responsible for intestinal and hepatobiliary cholesterol efflux, might simultaneously influence plasma and biliary cholesterol levels, and hence risk of myocardial infarction(MI) and gallstone disease in opposite di
PMID 24657701

Visible age-related signs and risk of ischemic heart disease in the general population: a prospective cohort study.

Christoffersen M1, Frikke-Schmidt R, Schnohr P, Jensen GB, Nordestgaard BG, Tybjærg-Hansen A.Author information 1Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark (M.C., R.F.-S.,A.T.-H.); The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen, Denmark (P.S., G.B.J., B.G.N., A.T.-H.); the Department of Cardiology, Hvidovre Hospital, Hvidovre, Denmark (G.B.J.); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen, Denmark (B.G.N.); and Copenhagen University Hospitals and Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark (M.C., R.F.-S., P.S., G.B.J., B.G.N., A.T.-H.).AbstractBACKGROUND: Cardiovascular disease is 1 of the most common age-related diseases, and also 1 of the most common causes of death in the general population. We tested the hypothesis that visible age-related signs associate with risk of ischemic heart disease (IHD), myocardial infarction (MI), and death in the general population, independent of chronological age.
Circulation.Circulation.2014 Mar 4;129(9):990-8. doi: 10.1161/CIRCULATIONAHA.113.001696. Epub 2013 Dec 13.
BACKGROUND: Cardiovascular disease is 1 of the most common age-related diseases, and also 1 of the most common causes of death in the general population. We tested the hypothesis that visible age-related signs associate with risk of ischemic heart disease (IHD), myocardial infarction (MI), and death
PMID 24334176

Assessment of cerebral tissue oxygen saturation in septic patients during acetazolamide provocation - A near infrared spectroscopy study.

Vaskó A, Siró P, László I, Szatmári S, Molnár L, Fülesdi B, Molnár C.Author information University of Debrecen Department of Anesthesiology and Intensive Care, Health and Medical Science Centre Nagyerdei krt. 98 H-4032 Debrecen Hungary.AbstractSepsis-associated encephalopathy is a multifactorially determined process of the brain parenchyma. Among other factors, vasogenic causes have been shown to play a role in its development. The aim of the present work was to assess whether cerebral tissue oxygen saturation is influenced by administration of acetazolamide in septic patients compared to controls.
Acta physiologica Hungarica.Acta Physiol Hung.2014 Mar;101(1):32-9. doi: 10.1556/APhysiol.101.2014.1.4.
Sepsis-associated encephalopathy is a multifactorially determined process of the brain parenchyma. Among other factors, vasogenic causes have been shown to play a role in its development. The aim of the present work was to assess whether cerebral tissue oxygen saturation is influenced by administrat
PMID 24631793

Japanese Journal

Catheter ablation of atrial fibrillation: Past, present, and future directions

Yoshida Kentaro,Aonuma Kazutaka
Journal of Arrhythmia 28(2), 83-90, 2012
… However, it is important to note that research into AF leads to better understanding of other cardiac and non-cardiac diseases because AF develops multifactorially in association with underlying systemic pathophysiologies. …
NAID 130002129513