月齢

WordNet

of long duration; not new; "old tradition"; "old house"; "old wine"; "old country"; "old friendships"; "old money"
past times (especially in the phrase `in days of old'
skilled through long experience; "an old offender"; "the older soldiers" (同)older
(used especially of persons) having lived for a relatively long time or attained a specific age; "his mother is very old"; "a ripe old age"; "how old are you?"
(used for emphasis) very familiar; "good old boy"; "same old story"
a time unit of approximately 30 days; "he was given a month to pay the bill"
of a very early stage in development; "Old English is also called Anglo Saxon"; "Old High German is High German from the middle of the 9th to the end of the 11th century"

PrepTutorEJDIC

『年とった』,老齢の / 『年上の』,年長の / 『ある年月』(『年齢』)『の』,…歳の / (物事が)『古い』,古くさい,新しくない / 《名詞の前にのみ用いて》『昔なじみの』,昔なつかしい / 《名詞の前にのみ用いて》『古代の』,大昔の / 《名詞の前にのみ用いて》(現在に対して)以前の,もとの / (衣服など)使い古した / (人が)経験のある,老練な / 《話》《呼び掛けで親しみなどをこめて》 / 《話》《名詞の前にのみ用い,前の形容詞を強めて》非常な,すばらしい / 昔
(また『calendar month』)(暦の上の1月から12月までのそれぞれの)『月』 / (ある日から翌月のその日までの)ひと月,1か月間 / (また『lunar month』)(太陰暦の)ひと月(月が地球の周りを1公転する期間;太陽暦では『solar month』)

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1. 小児における身体的診察：一般原則および標準的な測定 the pediatric physical examination general principles and standard measurements
2. プライマリケアにおける発達行動サーベイランスおよびスクリーニング developmental behavioral surveillance and screening in primary care
3. Incorporating residual kidney function into the dosing of intermittent hemodialysis
4. Evaluation and management of postmenopausal hyperandrogenism
5. 最新の診療アップデート practice changing updates

English Journal

Food restriction increases long-term memory persistence in adult or aged mice.

Talhati F1, Patti CL2, Zanin KA3, Lopes-Silva LB3, Ceccon LM1, Hollais AW1, Bizerra CS1, Santos R1, Tufik S4, Frussa-Filho R1.Author information 1Departamento de Farmacologia, Universidade Federal de São Paulo, R. Botucatu, 862, Ed. Leal Prado, 1° andar, 04023062, São Paulo, SP, Brazil.2Departamento de Farmacologia, Universidade Federal de São Paulo, R. Botucatu, 862, Ed. Leal Prado, 1° andar, 04023062, São Paulo, SP, Brazil. Electronic address: camila.patti@unifesp.br.3Departamento de Farmacologia, Universidade Federal de São Paulo, R. Botucatu, 862, Ed. Leal Prado, 1° andar, 04023062, São Paulo, SP, Brazil; Departamento de Psicobiologia, Universidade Federal de São Paulo, R. Napoleão de Barros, 925, 04024002, São Paulo, SP, Brazil.4Departamento de Psicobiologia, Universidade Federal de São Paulo, R. Napoleão de Barros, 925, 04024002, São Paulo, SP, Brazil.AbstractFood restriction (FR) seems to be the unique experimental manipulation that leads to a remarkable increase in lifespan in rodents. Evidences have suggested that FR can enhance memory in distinct animal models mainly during aging. However, only few studies systemically evaluated the effects FR on memory formation in both adult (3-month-old) and aged (18-24-month-old) mice. Thus, the aim of the present study was to investigate the effects of acute (12h) or repeated (12h/day for 2days) FR protocols on learning and memory of adult and aged mice evaluated in the plus-maze discriminative avoidance task (PM-DAT), an animal model that concurrently (but independently) evaluates learning and memory, anxiety and locomotion. We also investigated the possible role of FR-induced stress by the corticosterone concentration in adult mice. Male mice were kept at home cage with food ad libitum (CTRL-control condition) or subjected to FR during the dark phase of the cycle for 12h/day or 12h/2days. The FR protocols were applied before training, immediately after it or before testing. Our results demonstrated that only FR for 2days enhanced memory persistence when applied before training in adults and before testing in aged mice. Conversely, FR for 2days impaired consolidation and exerted no effects on retrieval irrespective of age. These effects do not seem to be related to corticosterone concentration. Collectively, these results indicate that FR for 2days can promote promnestic effects not only in aged mice but also in adults.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2014 Apr 3;50:125-36. doi: 10.1016/j.pnpbp.2013.12.007. Epub 2013 Dec 19.
Food restriction (FR) seems to be the unique experimental manipulation that leads to a remarkable increase in lifespan in rodents. Evidences have suggested that FR can enhance memory in distinct animal models mainly during aging. However, only few studies systemically evaluated the effects FR on mem
PMID 24361378

Modified toy cars for mobility and socialization: case report of a child with cerebral palsy.

Huang HH, Ragonesi CB, Stoner T, Peffley T, Galloway JC.Author information Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, Healthy Aging Research Center (Dr Huang), Chang Gung University, Kwei-Shan Tao-Yuan, Taiwan; Infant Behavior Lab, Department of Physical Therapy (Ms Peffley and Drs Ragonesi, Stoner, and Galloway) and Biomechanics and Movement Sciences Program (Drs Ragonesi and Galloway), University of Delaware, Newark, Delaware.AbstractPURPOSE: Children with cerebral palsy have limited opportunities to explore their physical and social environment. The purpose of this study was to determine the feasibility of using a "ride-on toy car" as a readily available, low-cost, fun, and functional option for children with special needs.
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association.Pediatr Phys Ther.2014 Spring;26(1):76-84. doi: 10.1097/PEP.0000000000000001.
PURPOSE: Children with cerebral palsy have limited opportunities to explore their physical and social environment. The purpose of this study was to determine the feasibility of using a "ride-on toy car" as a readily available, low-cost, fun, and functional option for children with special needs.METH
PMID 24263247

Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB.

Zhang J1, Jiang W2, Zuo Z3.Author information 1Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA; Department of Anesthesiology, Shanghai 6th People's Hospital, Shanghai Jiaotong University, Shanghai, China.2Department of Anesthesiology, Shanghai 6th People's Hospital, Shanghai Jiaotong University, Shanghai, China. Electronic address: jiangw@sjtu.edu.en.3Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA. Electronic address: zz3c@virginia.edu.AbstractSurgery induces learning and memory impairment. Neuroinflammation may contribute to this impairment. Nuclear factor κB (NF-κB) is an important transcription factor to regulate the expression of inflammatory cytokines. We hypothesize that inhibition of NF-κB by pyrrolidine dithiocarbamate (PDTC) reduces neuroinflammation and the impairment of learning and memory. To test this hypothesis, four-month-old male Fischer 344 rats were subjected to right carotid exploration under propofol and buprenorphine anesthesia. Some rats received two doses of 50mg/kg PDTC given intraperitoneally 30min before and 6h after the surgery. Rats were tested in the Barnes maze and fear conditioning paradigm begun 6days after the surgery. Expression of various proteins related to inflammation was examined in the hippocampus at 24h or 21days after the surgery. Here, surgery, but not anesthesia alone, had a significant effect on prolonging the time needed to identify the target hole during the training sessions of the Barnes maze. Surgery also increased the time for identifying the target hole in the long-term memory test and decreased context-related learning and memory in fear conditioning test. Also, surgery increased nuclear expression of p65, a NF-κB component, decreased cytoplasmic amount of inhibitor of NF-κB, and increased the expression of interleukin-1β, interleukin-6, ionized calcium binding adaptor molecule 1 and active matrix metalloproteinase 9 (MMP-9). Finally, surgery enhanced IgG extravasation in the hippocampus. These surgical effects were attenuated by PDTC. These results suggest that surgery, but not propofol-based anesthesia, induces neuroinflammation and impairment of learning and memory. PDTC attenuates these effects possibly by inhibiting NF-κB activation and the downstream MMP-9 activity.
Neuroscience.Neuroscience.2014 Mar 7;261:1-10. doi: 10.1016/j.neuroscience.2013.12.034. Epub 2013 Dec 21.
Surgery induces learning and memory impairment. Neuroinflammation may contribute to this impairment. Nuclear factor κB (NF-κB) is an important transcription factor to regulate the expression of inflammatory cytokines. We hypothesize that inhibition of NF-κB by pyrrolidine dithiocarbamate (PDTC) r
PMID 24365462

Japanese Journal

腎神経内分泌腫瘍(カルチノイド)の1例

稲垣裕介,藤田和利,中井康友,高山仁志,辻村晃,野々村祝夫
泌尿器科紀要 59(11), 723-727, 2013-11
… A 32-year-old man was referred to our hospital for treatment of left renal cystic tumor, which was detected by computed tomographic (CT) scan 3 years ago. … At the 9-month follow up, he had no evidence of local recurrence or metastasis. …
NAID 120005350253

地域住民のソーシャル・キャピタルと精神的健康との関連

播摩優子,佐々木久長,HARIMA Yuko,SASAKI Hisanaga
秋田大学大学院医学系研究科保健学専攻紀要 21(2), 97-111, 2013-10-31
… Regarding mental health, 18.6％ marked over K6 15 points, and 2.3％ had suicidal ideation within the last month. … The results indicated that the negative aspects of mental health (over K6 15 points and suicidal ideation within a month) were affected by age (over 80 years old), insufficient social support, and a lack of trust. …
NAID 120005348741

成人腸重積を契機に発見された小腸悪性リンパ腫の1例

久都内慶子,瀧野陽子,高田厚,河原正樹
東京女子医科大学雑誌 83(5), 363-366, 2013-10-25
症例は75歳女性.約2ヵ月前からしばしば腹痛を自覚していたが,突然の強い腹痛を自覚し救急要請,当院搬送となった.CTにて大腸腸重積と診断し、透視下に用手整復を施行し症状の改善をみた.精査にて回盲部に腫瘤を認めたため待機的な手術を予定していたところ,腹痛が再燃し緊急手術となった。術中Hutchinson手技を施行するも完全には整復されず回盲部切除術を施行した。切除検体では回腸末端に直径4cm程度の表 …
NAID 110009631876