WordNet

of or relating to an inheritable character that is controlled by a single pair of genes
an inherited disease controlled by a single pair of genes (同)monogenic disease

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/12/20 18:33:10」(JST)

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1. 単一遺伝子性疾患の非メンデル遺伝のパターン non mendelian inheritance patterns of monogenic diseases
2. メンデル遺伝の概要 overview of mendelian inheritance
3. 遺伝的変異の概要 overview of genetic variation
4. 高血圧の病因における遺伝的要因 genetic factors in the pathogenesis of hypertension
5. 小児や青年の高血圧の疫学、危険因子、および原因 epidemiology risk factors and etiology of hypertension in children and adolescents

No mutations in the serotonin related TPH1 and HTR1B genes in patients with monogenic sclerosing bone disorders.

Boudin E, Jennes K, de Freitas F, Tegay D, Mortier G, Van Hul W.SourceDepartment of Medical Genetics, University and University Hospital of Antwerp, Edegem, Belgium. Electronic address: eveline.boudin@ua.ac.be.
Bone.Bone.2013 Jul;55(1):52-6. doi: 10.1016/j.bone.2013.03.015. Epub 2013 Apr 3.
Since the identification of LRP5 as the causative gene for the osteoporosis pseudoglioma syndrome (OPPG) as well as the high bone mass (HBM) phenotype, LRP5 and the Wnt/β-catenin signaling have been extensively studied for their role in the differentiation and proliferation of osteoblasts, in the a
PMID 23563356

First successful double-factor PGD for Lynch syndrome: monogenic analysis and comprehensive aneuploidy screening.

Daina G, Ramos L, Obradors A, Rius M, Martinez-Pasarell O, Polo A, Del Rey J, Obradors J, Benet J, Navarro J.SourceCàtedra de Recerca Eugin-UAB; Unitat de Biologia Cel·lular i Genètica Mèdica, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Clinical genetics.Clin Genet.2013 Jul;84(1):70-3. doi: 10.1111/cge.12025. Epub 2012 Oct 17.
Preimplantation genetic diagnosis (PGD) has been applied worldwide for a great variety of single-gene disorders over the last 20 years. The aim of this work was to perform a double-factor preimplantation genetic diagnosis (DF-PGD) protocol in a family at risk for Lynch syndrome. The family underwe
PMID 22998423

Prevalence of monogenic diabetes in the population-based Norwegian Childhood Diabetes Registry.

Irgens HU, Molnes J, Johansson BB, Ringdal M, Skrivarhaug T, Undlien DE, Søvik O, Joner G, Molven A, Njølstad PR.SourceKG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
Diabetologia.Diabetologia.2013 Jul;56(7):1512-9. doi: 10.1007/s00125-013-2916-y. Epub 2013 Apr 27.
AIMS/HYPOTHESIS: Monogenic diabetes (MD) might be misdiagnosed as type 1 diabetes. The prevalence of MD among children with apparent type 1 diabetes has not been established. Our aim was to estimate the prevalence of common forms of MD in childhood diabetes.METHODS: We investigated 2,756 children ag
PMID 23624530