micrometastasis

微小転移

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/28 19:04:01」(JST)

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Micrometastasis is a form of metastasis (the spread of a cancer from its original location to other sites in the body) in which the newly formed tumors are too minuscule to be detected

Adjuvant chemotherapy and adjuvant radiotherapy are directed at killing any micrometastases, thus preventing relapse (regrowth of the cancer) and the (likely) death of the patient. Early detection of micrometastases could identify the patients who are most (and least) likely to benefit from adjuvant therapy.

See also

• Metastasis
• Adjuvant chemotherapy

References

UpToDate Contents

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• 1. 乳癌における診断、ステージング、およびリンパ節評価におけるセンチネルリンパ節生検の役割 diagnosis staging and the role of sentinel lymph node biopsy in the nodal evaluation of breast cancer
• 2. 黒色腫（メラノーマ）における所属リンパ節の病理学的評価 pathologic evaluation of regional lymph nodes in melanoma
• 3. 微小浸潤乳癌 microinvasive breast carcinoma
• 4. 皮膚黒色腫におけるtumor node metastasis（TNM）病期分類法およびその他の予後因子 tumor node metastasis tnm staging system and other prognostic factors in cutaneous melanoma
• 5. 子宮頸癌に対する妊孕性温存手術 fertility sparing surgery for cervical cancer

English Journal

• Intraoperative fluorescence imaging to localize tumors and sentinel lymph nodes in rectal cancer.

• Handgraaf HJ1, Boogerd LS1, Verbeek FP1, Tummers QR1, Hardwick JC2, Baeten CI1, Frangioni JV3,4,5, van de Velde CJ1, Vahrmeijer AL1.
• Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy.Minim Invasive Ther Allied Technol.2016 Feb;25(1):48-53. doi: 10.3109/13645706.2015.1042389. Epub 2015 May 7.
• Tumor involvement at the resection margin remains the most important predictor for local recurrence in patients with rectal cancer. A careful description of tumor localization is therefore essential. Currently, endoscopic tattooing with ink is customary, but visibility during laparoscopic resections
• PMID 25950124

• Sentinel Lymph Node in Breast Cancer: Review Article from a Pathologist's Point of View.

• Apple SK.
• Journal of pathology and translational medicine.J Pathol Transl Med.2016 Jan 12. doi: 10.4132/jptm.2015.11.23. [Epub ahead of print]
• Breast cancer staging, in particular N-stage changed most significantly due to the advanced technique of sentinel lymph node biopsy two decades ago. Pathologists have more thoroughly examined and scrutinized sentinel lymph node and found increased number of small volume metastases. While pathologist
• PMID 26757203

• Human Adipose Tissue-Derived Stromal/Stem Cells Promote Migration and Early Metastasis of Head and Neck Cancer Xenografts.

• Rowan BG1, Lacayo EA1, Sheng M1, Anbalagan M1, Gimble JM1, Jones RK1, Joseph WJ1, Friedlander PL1, Chiu ES1.
• Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery.Aesthet Surg J.2016 Jan;36(1):93-104. doi: 10.1093/asj/sjv090. Epub 2015 Jun 10.
• BACKGROUND: Fat grafting has become popular for repair of postsurgical/postradiation defects after head/neck cancers resection. Fat graft supplementation with adipose tissue-derived stromal/stem cells (ASCs) is proposed to improve graft viability/efficacy, although the impact of ASCs on head/neck ca
• PMID 26063833

Japanese Journal

• Assessment of Melanoma-Initiating Cell Markers and Conventional Parameters in Sentinel Lymph Nodes of Malignant Melanoma

• Suzuki Norihiro,Takata Minoru,Shirafuji Yoshinori,Otsuka Masaki,Yamasaki Osamu,Asagoe Kenji,Hatta Naohito,Iwatsuki Keiji
• Acta Medica Okayama 69(1), 17-27, 2015-02
• … The presence of micrometastasis was confirmed immunohistochemically using antibodies to S-100, HMB-45, MART-1, and tyrosinase. … Discordance between immunohistochemical and molecular data was observed in 14 of 70 (20.0%) patients, among whom five (7.1%) were positive for only molecular markers;two of these five patients tested positive for micrometastasis by repeated immunohistochemical stainings. …
• NAID 120005549933

• Proposed new lymphology combined with lymphatic physiology, innate immunology, and oncology

• Ohhashi Toshio,Kawai Yoshiko
• The journal of physiological sciences 65(1), 51-66, 2015-01
• NAID 40020323553

• Clinical implications of quantitative pathological and immunohistochemical markers for lymph node metastasis in esophageal cancer patients based on preoperative treatment status

• Kinjo Tatsuya,Shimoji Hideaki,Nagahama Masayoshi [他]
• Esophagus : official journal of the Japan Esophageal Society 11(4), 238-244, 2014-09
• NAID 40020229806

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