メタサイクリン
- 関
- methacycline、methacycline hydrochloride
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/05/21 16:01:53」(JST)
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Metacycline
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Systematic (IUPAC) name |
(2Z,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylene-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
MedlinePlus |
a682778 |
Pregnancy cat. |
? |
Legal status |
? |
Identifiers |
ATC code |
J01AA05 |
PubChem |
CID 5281054 |
ChemSpider |
10468596 Y |
UNII |
IR235I7C5P N |
ChEMBL |
CHEMBL249837 N |
NIAID ChemDB |
001301 |
Chemical data |
Formula |
C22H22N2O8 |
Mol. mass |
442.419 g/mol |
SMILES |
eMolecules & PubChem |
InChI
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InChI=1S/C22H22N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31)/t10-,14-,15+,17+,22+/m1/s1 Y
Key:MHIGBKBJSQVXNH-IWVLMIASSA-N Y
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N (what is this?) (verify)
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Metacycline is a tetracycline antibiotic. It is used as a precursour in the industrial synthesis of doxycycline hyclate. It should not be confused with the antibiotic methicillin (aka meticillin).
Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)
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30S |
Aminoglycosides
(initiation inhibitors) |
-mycin (Streptomyces) |
- Streptomycin#
- Dihydrostreptomycin
- Neomycin#
- Framycetin
- Paromomycin
- Ribostamycin
- Kanamycin#
- Amikacin
- Arbekacin
- Bekanamycin
- Dibekacin
- Tobramycin
- Spectinomycin#
- Hygromycin B
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-micin (Micromonospora) |
- Gentamicin#
- Netilmicin
- Sisomicin
- Isepamicin
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Tetracycline antibiotics
(tRNA binding) |
Tetracyclines |
- Doxycycline#
- Chlortetracycline
- Clomocycline
- Demeclocycline
- Lymecycline
- Meclocycline
- Metacycline
- Minocycline
- Oxytetracycline
- Penimepicycline
- Rolitetracycline
- Tetracycline
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Glycylcyclines |
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50S |
Oxazolidinone
(initiation inhibitors) |
- Linezolid
- Torezolid
- Eperezolid
- Posizolid
- Radezolid
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Peptidyl transferase |
Amphenicols |
- Chloramphenicol#
- Azidamfenicol
- Thiamphenicol
- Florfenicol
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Pleuromutilins |
- Retapamulin
- Tiamulin
- Valnemulin
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MLS (transpeptidation/translocation) |
Macrolides |
- Azithromycin#
- Clarithromycin
- Dirithromycin
- Erythromycin#
- Flurithromycin
- Josamycin
- Midecamycin
- Miocamycin
- Oleandomycin
- Rokitamycin
- Roxithromycin
- Spiramycin
- Troleandomycin
- Tylosin
- Ketolides
- Telithromycin
- Cethromycin
- Solithromycin
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Lincosamides |
- Clindamycin#
- Lincomycin
- Pirlimycin
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Streptogramins |
- Pristinamycin
- Quinupristin/dalfopristin
- Virginiamycin
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EF-G |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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gr+f/gr+a(t)/gr-p(c)/gr-o
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English Journal
- Antibiotics in the coastal environment of the Hailing Bay region, South China Sea: Spatial distribution, source analysis and ecological risks.
- Chen H1, Liu S2, Xu XR3, Zhou GJ2, Liu SS4, Yue WZ2, Sun KF2, Ying GG4.
- Marine pollution bulletin.Mar Pollut Bull.2015 Jun 15;95(1):365-73. doi: 10.1016/j.marpolbul.2015.04.025. Epub 2015 Apr 22.
- In this study, the occurrence and spatial distribution of 38 antibiotics in surface water and sediment samples of the Hailing Bay region, South China Sea, were investigated. Twenty-one, 16 and 15 of 38 antibiotics were detected with the concentrations ranging from <0.08 (clarithromycin) to 15,163
- PMID 25913795
- pH-dependent spectroscopy of tetracycline and its analogs.
- Mojica ER1, Nguyen E, Rozov M, Bright FV.
- Journal of fluorescence.J Fluoresc.2014 Jul;24(4):1183-98. doi: 10.1007/s10895-014-1399-7. Epub 2014 May 9.
- Tetracyclines (TCs), broad spectrum antibiotics widely used in the prevention and treatment of infectious diseases, are amphoteric molecules containing several ionizable functional groups that exist predominantly as zwitterions at a given pH value. TCs are reported to undergo a wide variety of react
- PMID 24806484
- Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline.
- Xi Y1, Tan K, Brumwell AN, Chen SC, Kim YH, Kim TJ, Wei Y, Chapman HA.
- American journal of respiratory cell and molecular biology.Am J Respir Cell Mol Biol.2014 Jan;50(1):51-60. doi: 10.1165/rcmb.2013-0099OC.
- A high-throughput small-molecule screen was conducted to identify inhibitors of epithelial-mesenchymal transition (EMT) that could be used as tool compounds to test the importance of EMT signaling in vivo during fibrogenesis. Transforming growth factor (TGF)-β1-induced fibronectin expression and E-
- PMID 23944988
Japanese Journal
- Lysozyme-Enhanced Europium(III)-Metacycline Luminescence and Its Application to the Determination of Metacycline
- Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 21(5), 541-544, 2005-05-10
- NAID 10015717745
- 膿皮症に対するMetacycline Hydrochlorideの臨床的検討
- 膿皮症に対するMetacycline Hydrochlorideの臨床的検討
Related Links
- Metacyclineとは?goo Wikipedia (ウィキペディア) 。出典:Wikipedia(ウィキペディア)フリー百科事典。 Metacyclineとは - goo Wikipedia (ウィキペディア) gooトップ サイトマップ スタートページに設定 RSS ヘルプ メニューへスキップ ...
- Metacycline is a medicine available in a number of countries worldwide. A list of US medications equivalent to Metacycline is available on the Drugs.com website. ... Drugs.com provides accurate and independent information on more ...
Related Pictures
★リンクテーブル★
[★]
- 英
- methacycline MTC、metacycline
- ラ
- metacyclinum
- 化
- 塩酸メタサイクリン methacycline hydrochloride
[★]
- 関
- metacycline、methacycline