流量
WordNet
- a state of uncertainty about what should be done (usually following some important event) preceding the establishment of a new direction of action; "the flux following the death of the emperor" (同)state of flux
- a substance added to molten metals to bond with impurities that can then be readily removed
- excessive discharge of liquid from a cavity or organ (as in watery diarrhea)
- the rate of flow of energy or particles across a given surface
- in constant change; "his opinions are in flux"; "the newness and flux of the computer industry"
- a flow or discharge (同)fluxion
- of or relating to metabolism; "metabolic rate"
- undergoing metamorphosis (同)metabolous
PrepTutorEJDIC
- 流動,流れ;上げ潮 / 絶え間ない変化,流転(るてん) / 融剤,フラックス / (流体・粒子・エネルギーの)流量,流束,流動率 / (電気・磁気の)束(そく) / (体内の液体の)異常流出,異常排出
- 新陳代謝の
- インフルエンザ,流感
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/20 23:00:30」(JST)
[Wiki en表示]
Not to be confused with Magnetic_flux.
For other uses of "Flux", see Flux (disambiguation).
Flux, or metabolic flux is the rate of turnover of molecules through a metabolic pathway. Flux is regulated by the enzymes involved in a pathway. Within cells, regulation of flux is vital for all metabolic pathways to regulate the metabolic pathway's activity under different conditions.[1][2] Flux is therefore of great interest in metabolic network modelling, where it is analysed via flux balance analysis.
Existing metabolic networks regulate the movement of chemicals through their enzymatic steps by mostly regulating enzymes that catalyze irreversible reactions, while the movement of chemicals through reversible steps is generally unregulated directly.[1][2] As a result, the movement of precursors/products through a metabolic network is governed by simple chemical equilibria, with specific key enzymes that are subject to regulation. This regulation may be indirect, in the case of an enzyme being regulated by some cell signalling mechanism, or it may be direct, as in the case of allosteric regulation, where metabolites from a different portion of a metabolic network bind directly to and affect the catalytic function of other enzymes in order to maintain homeostasis.
In this manner, flux is the movement of matter through metabolic networks that are connected by chemical equilibria, and is therefore a way of describing the activity of the metabolic network as a whole using a single characteristic.
References
- ^ a b "Lehninger's Principles of Biochemistry", 4th edition, pp. 571 and 592, 2004.
- ^ a b "Voet's Biochemistry", 2nd edition, pp. 439, 1995.
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 透析の方法および患者の転帰dialysis modality and patient outcome [show details]
…perhaps other factors may lead to higher patient survival with high-flux dialysis . The question of a possible survival benefit with high-flux dialysis was best addressed in a large, randomized clinical trial …
- 2. 末期腎疾患における他の腎代替療法alternative renal replacement therapies in end stage kidney disease [show details]
… Renal replacement therapy in its current forms does not replace the metabolic and endocrine functions of the renal tubular cells.… survival compared with high-flux hemodialysis (HR 0.70, 95% CI 0.46-1.08). The ESHOL trial randomly assigned 906 patients to either high-flux hemodialysis (450 patients) or on-line…
- 3. 血液透析膜の生体適合性についての臨床結果clinical consequences of hemodialysis membrane biocompatibility [show details]
…predialysis from patients chronically dialyzed with cellulosic membranes have a significantly attenuated metabolic response to phagocytic stimuli such as latex or zymosan when compared with neutrophils from patients…
- 4. 適切な血液透析の実施および評価prescribing and assessing adequate hemodialysis [show details]
… control, a review of intradialytic or interdialytic symptoms, and laboratory monitoring for anemia, metabolic bone disease, and electrolyte disturbances. However, there is a paucity of evidence to support… Dialysis is now more commonly performed with large-pore high-flux dialysis membranes,…
- 5. 高用量メトトレキサートの治療使用および毒性therapeutic use and toxicity of high dose methotrexate [show details]
… (leucovorin, also called folinic acid, N5-formyl-tetrahydrofolate, citrovorum factor) to bypass the metabolic block induced by MTX . In these pioneering experiments, administration of leucovorin within 24 to … high-flux hemodialysis (n = 9), and charcoal hemofiltration (n = 7); 16 patients were treated with multiple modalities. High-flux hemodialysis resulted in the greatest…
English Journal
Japanese Journal
- Comparative metabolic flux analysis of an Ashbya gossypii wild type strain and a high riboflavin-producing mutant strain(BIOCHEMICAL ENGINEERING)
- Jeong Bo-Young,Wittmann Christoph,Kato Tatsuya [他],Park Enoch Y.
- Journal of bioscience and bioengineering 119(1), 101-106, 2015-01
- NOTICE: this is the author's version of a work that was accepted for publication in Journal of Bioscience and Bioengineering. Changes resulting from the publishing process, such as peer review, editin …
- NAID 110009892242
- Recent advances to improve fermentative butanol production : Genetic engineering and fermentation technology
- Zheng Jin,Tashiro Yukihiro,Wang Qunhui,Sonomoto Kenji
- Journal of bioscience and bioengineering 119(1), 1-9, 2015-01
- … Genetic engineering is now available for improving butanol yield and butanol ratio through overexpression, knock out/down, and insertion of genes encoding key enzymes in the metabolic pathway of butanol fermentation. …
- NAID 110009892226
- C-3 左右差を考慮した人体7部位への局所熱刺激に対する人体温熱生理反応(セッションC)
- 内和田 雅哉,島崎 康弘,野津 滋
- 人間-生活環境系シンポジウム報告集 38, 153-156, 2014-11-20
- 局所熱刺激を人体へ付与した際の人体温熱生理反応を把握するために,人体の生理的情報である皮膚表面熱流束,皮膚温,代謝率,心拍数と心理情報である温冷感や温熱的快適感を計測した.本実験は,3つの環境下で行われ,局所熱刺激は左右を含む人体主要七箇所に付与した.実験結果として,環境温は人体温熱生理反応に影響を与えた.この要因は,主に人体温熱状態を維持するために,皮膚温が環境によって変動するためである.また, …
- NAID 110009878868
Related Links
- Flux balance analysis is a mathematical approach for analyzing the flow of metabolites through a metabolic network. This primer covers the theoretical basis of the approach, several practical examples and a software ...
- こんにちは、B&Mの大賀です。いまアツいメタボローム解析とは？第一弾、代謝フラックス解析のレビュー3報目のご紹介です。 3報目は、微生物の醗酵育種にフォーカスして、特に解析理論が詳しく説明されている最新のレビューです。
★リンクテーブル★
[★]
- 関
- flow、mobilization、solvent、stream、streaming
[★]
- 関
- metabolically
[★]
- 関
- grippe、influenza