- 関
- biotransformation
WordNet
- making active and effective (as a bomb)
- stimulation of activity in an organism or chemical
- of or relating to metabolism; "metabolic rate"
- undergoing metamorphosis (同)metabolous
PrepTutorEJDIC
- 活動化 / (物質の)活性化(化学反応を起こしやすくすること)
- 新陳代謝の
UpToDate Contents
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English Journal
- Hepatic biotransformation of alkylresorcinols is mediated via cytochrome P450 and β-oxidation: A proof of concept study.
- Marklund M, McKeown NM, Blumberg JB, Chen CY.SourceJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA.
- Food chemistry.Food Chem.2013 Aug 15;139(1-4):925-30. doi: 10.1016/j.foodchem.2013.01.122. Epub 2013 Feb 13.
- Alkylresorcinols (AR) are phenolic lipids present in the bran of some cereals. AR may serve as a biomarker for whole grain wheat and rye intake. While AR pharmacokinetics and two major metabolites have been reported, the metabolic pathways contributing to their relatively rapid elimination from the
- PMID 23561191
- Croton lechleri Müll. Arg. (Euphorbiaceae) stem bark essential oil as possible mutagen-protective food ingredient against heterocyclic amines from cooked food.
- Rossi D, Guerrini A, Paganetto G, Bernacchia G, Conforti F, Statti G, Maietti S, Poppi I, Tacchini M, Sacchetti G.SourceDipartimento di Scienze della Vita e Biotecnologie (SVeB) - LT Terra&Acqua Tech UR7, Università degli Studi di Ferrara, C.so Ercole I d'Este 32, I-44121 Ferrara, Italy.
- Food chemistry.Food Chem.2013 Aug 15;139(1-4):439-47. doi: 10.1016/j.foodchem.2013.01.076. Epub 2013 Feb 7.
- The Amazonian Croton lechleri stem bark essential oil was tested for its anti-mutagenic potential by performing the Ames test against heterocyclic amines (HCAs), in continuing research on applicative functional profile of this phytocomplex as food ingredient (Rossi et al., 2011). Salmonella typhimur
- PMID 23561129
- A new process for obtaining hydroxytyrosol using transformed Escherichia coli whole cells with phenol hydroxylase gene from Geobacillus thermoglucosidasius.
- Orenes-Piñero E, García-Carmona F, Sánchez-Ferrer A.SourceDepartment of Biochemistry and Molecular Biology-A, Faculty of Biology, Regional Campus of International Excellence Campus Mare Nostrum, University of Murcia, Campus Espinardo, E-30100 Murcia, Spain.
- Food chemistry.Food Chem.2013 Aug 15;139(1-4):377-83. doi: 10.1016/j.foodchem.2012.12.063. Epub 2013 Feb 1.
- Phenol hydroxylase gene cloning from the thermophilic bacteria Geobacillus thermoglucosidasius was used to develop an effective method to convert tyrosol into the high-added-value compound hydroxytyrosol by hydroxylation. Phenol hydroxylase is a two-component enzyme encoded by pheA1 and pheA2 genes
- PMID 23561120
Japanese Journal
- Oxidation of N-Alkyl-N-(3-carboxypropyl)nitrosamines by Iron Porphyrin and Oxidant Forms Alkylating Mutagens
- Inami Keiko,Yasui Hiroki,Tsugumi Hirotaka [他]
- Genes and environment : the official journal of the Japanese Environmental Mutagen Society 35(4), 99-104, 2013-11
- NAID 40019868021
- α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells
- Michikoshi Hiromitsu,Nakamura Takahiro,Sakai Katsuya,Suzuki Yoshinori,Adachi Eri,Matsugo Seiichi,Matsumoto Kunio
- Cancer Letters 335(2), 472-478, 2013-07-28
- … α-Lipoic acid (α-LA), a naturally occurring anti-oxidant and co-factor for metabolic enzymes, suppresses the growth of different types of tumor cells. … In the present study, we investigated the effects of α-LA on the proliferation and activation status of definitive receptor tyrosine kinases, epidermal growth factor receptor (EGFR) and Met/hepatocyte growth factor (HGF) receptor, in gefitinib-sensitive human non-small cell lung cancer cells harboring EGFRs with an activating mutation. …
- NAID 120005254051
- The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
- Kimura Ikuo,Ozawa Kentaro,Inoue Daisuke,Imamura Takeshi,Kimura Kumi,Maeda Takeshi,Terasawa Kazuya,Kashihara Daiji,Hirano Kanako,Tani Taeko,Takahashi Tomoyuki,Miyauchi Satoshi,Shioi Go,Inoue Hiroshi,Tsujimoto Gozoh
- Nature communications 4, 2013-05-07
- … Here we show that the short-chain fatty acid receptor GPR43 links the metabolic activity of the gut microbiota with host body energy homoeostasis. … We further show that short-chain fatty acid-mediated activation of GPR43 suppresses insulin signalling in adipocytes, which inhibits fat accumulation in adipose tissue and promotes the metabolism of unincorporated lipids and glucose in other tissues. …
- NAID 120005244704
Related Links
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- 1. Cancer Cell. 2014 Oct 13;26(4):549-64. doi: 10.1016/j.ccell.2014.09.003. Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes. Wolf MJ ...
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★リンクテーブル★
[★]
- 関
- biotransform、biotransformed、metabolic activation
[★]
- 英
- metabolic activation
- 関
- 生体内変換
[★]
- 関
- metabolically
[★]
- 関
- activate、activated、turn on