関: oropharyngeal cancer

WordNet

any malignant tumor derived from epithelial tissue; one of the four major types of cancer

PrepTutorEJDIC

がん,がん腫

English Journal

[Delayed laryngeal nerve paralysis after lung cancer surgery; report of a case].

Watanabe F, Kogure S, Yamamoto N, Fujii T, Yuasa U, Tokui T.Author information Department of Thoracic Surgery, Ise Red Cross Hospital, Ise, Japan.AbstractA 75-year-old woman with mesopharyngeal adenocarcinoma underwent left upper lobectomy for lung adenocarcinoma. Before the operation, computed tomography showed no stricture of the trachea, and laryngoscope showed no abnormality of vocal cord. Spiral tube( 7.5 mm I.D.) was used instead. One lung ventilation was achieved using balloon. It took 4 hours and 3 minutes to finish the surgical procedure. After extubation in the operation room, we did not recognize the breathing abnormality and laryngeal nerve palsy. 4 days after the operation, stridor was noticed, and laryngoscopic examination revealed stenosis of glottis due to bilateral laryngeal nerve paralysis. We performed the emergent tracheotomy. 7 days after the operation, nerve paralysis improved.
Kyobu geka. The Japanese journal of thoracic surgery.Kyobu Geka.2013 May;66(5):427-30.
A 75-year-old woman with mesopharyngeal adenocarcinoma underwent left upper lobectomy for lung adenocarcinoma. Before the operation, computed tomography showed no stricture of the trachea, and laryngoscope showed no abnormality of vocal cord. Spiral tube( 7.5 mm I.D.) was used instead. One lung vent
PMID 23674045

Effects of cytochrome P450 1A1 and uridine-diphosphate-glucuronosyltransferase 1A1 allelic polymorphisms on the risk of development and the prognosis of head and neck cancers.

Szanyi I, Ráth G, Móricz P, Somogyvári K, Révész P, Gerlinger I, Orsós Z, Ember I, Kiss I.Author information Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Pécs University, Pécs, Hungary. istvan.szanyi@gmail.comAbstractWe studied the effect of allelic polymorphisms of cytochrome P450 1A1 (CYP1A1) and uridine-diphosphate-glucuronosyltransferase 1A1 (UGT1A1) on the risk of development of head and neck cancers and overall survival. One hundred and forty-two head and neck cancer patients (48 with laryngeal, 42 with hypopharyngeal and 52 with mesopharyngeal tumours) were included in the study. The control group (150 individuals) included volunteers without malignant tumours. There was no statistically significant difference in age, sex distribution, or smoking habits between the two groups. The participants were genotyped for the CYP1A1 isoleucine/valine (Ile/Val) polymorphism in exon 7 and for the UGT1A1 thymine-adenine-repeat polymorphism (*1 and *28 alleles) in the promoter region of the gene. The effect of the allelic variants on survival was studied using the log-rank test, whereas the χ-test and odds ratios (OR) with 95% confidence intervals (CI) were used to compare the allelic frequencies between patients and controls. Our study revealed a significant link between the occurrence of the CYP1A1 Ile/Val, Val/Val (OR: 1.72, 95% CI: 1.02-2.96, P=0.044) and UGT1A1*28 alleles (OR: 2.74, 95% CI: 1.45-5.18, P=0.002) and an increased risk of head and neck cancers. These alleles decreased the duration of survival significantly (P=0.018 and 0.006). The survival was significantly more strongly reduced when the two high-risk alleles were carried simultaneously (OR: 2.149, 95% CI: 1.111-4.157, P=0.001). Our results suggest that the use of the CYP1A1 Ile/Val and Val/Val variants and UGT1A1*28 as biomarkers can aid risk assessment while their prognostic value can aid planning of individual therapy.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).Eur J Cancer Prev.2012 Nov;21(6):560-8.
We studied the effect of allelic polymorphisms of cytochrome P450 1A1 (CYP1A1) and uridine-diphosphate-glucuronosyltransferase 1A1 (UGT1A1) on the risk of development of head and neck cancers and overall survival. One hundred and forty-two head and neck cancer patients (48 with laryngeal, 42 with hy
PMID 22273851

Autologus groin lymph node transfer for “sentinel lymph network” reconstruction after head-and-neck cancer resection and neck lymph node dissection: a case report.

Mihara M, Iida T, Hara H, Hayashi Y, Yamamoto T, Narushima M, Hayami S, Sawamoto N, Naito M, Koshima I.Author information Department of Plastic and Reconstructive Surgery, University of Tokyo,Tokyo, Japan. mihara@keiseigeka.nameAbstractLocal or distant metastatic recurrence after therapy is observed in 20–30% of cases of head-and-neck cancer. An unfavorable course may occur after cervical lymph node dissection due to loss of immunoprotective lymph nodes in the head-and-neck region. To overcome this problem, we performed autologous lymph node transplantation from the groin after head-and-neck cancer resection and cervical lymph node dissection. The patient was a 63-year-old man with squamous cell carcinoma in the mesopharyngeal lateral wall. After tumor resection and right cervical lymph node dissection, a lymph node-containing superficial circumflex iliac artery perforator flap was transplanted from the left groin. Pathological examination showed that cancer had invaded the primary tumor tissue stump. Thus, radiotherapy (66 Gy) was performed for the residual tumor from days 28 to 84 after surgery. At 12 months after surgery, no recurrent lesion or has developed. The biopsy of flap and lymphatic vessel endothelial hyaluronan receptor-1 (LYVE1) immunostaining shows creditable lymph network in the flap, compared with normal free flap. This case suggests that autologous lymph node transplantation may keep watch on cancer recurrence by reconstruction of the lymph node system in the resected region, and we suggest that this approach may be very useful in cancer therapy.
Microsurgery.Microsurgery.2012 Feb;32(2):153-7. doi: 10.1002/micr.20970.
Local or distant metastatic recurrence after therapy is observed in 20–30% of cases of head-and-neck cancer. An unfavorable course may occur after cervical lymph node dissection due to loss of immunoprotective lymph nodes in the head-and-neck region. To overcome this problem, we performed autologo
PMID 22389902