WordNet

street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
having the characteristics of an acid; "an acid reaction"
the inflection of verbs
a class of verbs having the same inflectional forms
the complete set of inflected forms of a verb

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1. バルプロ酸中毒valproic acid poisoning [show details]
… distribution (0.13 to 0.23 L/kg) . VPA is metabolized extensively by the liver via glucuronic acid conjugation and beta and omega oxidation to produce multiple metabolites, some of which are biologically …
2. 尿酸腎結石症uric acid nephrolithiasis [show details]
… discussed separately. The two major factors that promote uric acid precipitation are a high urine uric acid concentration and an acid urine pH, which drives the following reaction toward the right, converting …
3. 胃酸分泌の生理学physiology of gastric acid secretion [show details]
…deficient mice and HDC-knockout mice have near normal basal acid secretion, a preserved acid secretory response to cholinergic agents, an absent acid secretory response to exogenous gastrin, and hypergastrinemia …
4. 尿酸による腎疾患uric acid renal diseases [show details]
… separately. Uric acid is a weak organic acid and exists in one of two forms in biological systems, depending upon the prevailing pH : the sparingly soluble undissociated uric acid form (the most highly …
5. 妊娠中の葉酸補充folic acid supplementation in pregnancy [show details]
…consume some folic acid as folate is a natural component of a variety of foods, and grain products in many countries are fortified with folic acid. This topic will discuss the role of folic acid supplementation …

Influence of glutathione-S-transferase (GST) inhibition on lung epithelial cell injury: role of oxidative stress and metabolism.

Fletcher ME1, Boshier PR2, Wakabayashi K1, Keun HC3, Smolenski RT4, Kirkham PA5, Adcock IM6, Barton PJ6, Takata M1, Marczin N7.
American journal of physiology. Lung cellular and molecular physiology.Am J Physiol Lung Cell Mol Physiol.2015 Jun 15;308(12):L1274-85. doi: 10.1152/ajplung.00220.2014. Epub 2015 Apr 10.
Oxidant-mediated tissue injury is key to the pathogenesis of acute lung injury. Glutathione-S-transferases (GSTs) are important detoxifying enzymes that catalyze the conjugation of glutathione with toxic oxidant compounds and are associated with acute and chronic inflammatory lung diseases. We hypot
PMID 26078397

Identification of the metabolites of Ixerin Z from Ixeris sonchifolia Hance in rats by HPLC-LTQ-Orbitrap mass spectrometry.

Cai W1, Zhang JY2, Dong LY1, Yin PH1, Wang CG2, Lu JQ3, Zhang HG4.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Mar 25;107:290-7. doi: 10.1016/j.jpba.2015.01.004. Epub 2015 Jan 10.
Ixerin Z, one of major sesquiterpene lactones from Ixeris sonchifolia Hance, was considered to be a major active compound because of their special structure and activity. However, studies on Ixerin Z metabolism have rarely been reported. This study is the first to investigate the in vivo metabolism
PMID 25636166

In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells.

Ibie C1, Knott R1, Thompson CJ1.
International journal of pharmaceutics.Int J Pharm.2015 Feb 1;479(1):103-17. doi: 10.1016/j.ijpharm.2014.12.058. Epub 2014 Dec 27.
The biocompatibility and cellular uptake of polymer, insulin polyelectrolyte complexes (PECs) prepared using polyallylamine-based polymers was evaluated in-vitro using Caco-2 cell monolayers as a predictive model for human small intestinal epithelial cells. Poly(allyl amine) (PAA) and Quaternised PA
PMID 25549853

Hepatotoxicity and Immunotoxicity of 1-Bromohexane and Its Glutathione Conjugation in Female BALB/c Mice

, , [他], , , , , , ,
Journal of Health Science 56(4), 434-441, 2010
… Hepatotoxic and immunotoxic effects of 1-bromohexane (1-BH) and its conjugation with glutathione (GSH) were investigated in female BALB/c mice. … The hepatic contents of thiobarbituric acid reactive substances were significantly increased at 2000 mg/kg of 1-BH from 12 to 24 hr after the treatment. …
NAID 130000303542

Compensatory Expression of MRP3 in the Livers of MRP2-Deficient EHBRs Is Promoted by DHA Intake

, ,
Bioscience, biotechnology, and biochemistry 73(11), 2432-2438, 2009-11-23
… We have hypothesized a suppressive mechanism against dietary docosahexaenoic acid (22:6n-3; … In the livers of the DHA-fed rats, the level of free malondialdehyde (MDA) + 4-hydroxy-2-alkenals (HAE) fell, and conversely glutathione <I>S</I>-transferase (GST) activity increased in MRP2-deficient EHBRs as compared to the SDRs, suggesting that the glutathione (GSH)-conjugation reaction for the aldehydes generated on DHA intake was accelerated in the MRP2-deficient EHBRs. …
NAID 10027547717

化学物質汚染の基本課題としての揮発性炭化水素類問題（３）―生体内活性酸素との反応に関連したメチルベンゼン類の生体影響と室内汚染問題―:－生体内活性酸素との反応に関連したメチルベンゼン類の生体影響と室内汚染問題－

田中正宣
生活衛生 49(1), 3-23, 2005
… In these methylbenzenes, the main metabolic route is the methyl group oxidation (benzylalchols) → benzoic acids → hippuric acids (glycine conjugation), which is regarded as less toxic. … By way of example, benzoic acid is easily metabolized to form hippuric acid in urine, which is permissible for the high level usage of food additives. … In particular, the mercapturic acids and phenols are notable in o-xylene and trimethylbenzenes with three methyl groups. …
NAID 130004809624