出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/12/28 11:15:30」(JST)
| Dura mater | |
|---|---|
| Meninges of the CNS | |
| The dura mater extends into the skull cavity as the falx cerebri and tentorium cerebelli etc. | |
| Latin | Dura mater |
| Gray's | subject #193 872 |
| MeSH | Dura+Mater |
| Code | TA A14.1.01.101 |
Dura mater (UK /ˈdjʊərə ˈmeɪtər/ or US /ˈdʊərə ˈmætr/), or dura, is a thick membrane that is the outermost of the three layers of the meninges that surround the brain and spinal cord. It is derived from mesoderm.
The two meningeal layers are the pia mater and the arachnoid mater. The dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid. The name dura mater derives from the Latin for tough mother, a loan translation of Arabic أم الدماغ الصفيقة (umm al-dimāgh aṣ-ṣafīqah), literally thick mother of the brain, matrix of the brain.[1][2] and is also referred to by the term "pachymeninx" (plural "pachymeninges"). The dura has been described as "tough and inflexible" and "leather-like".[1]
The dura mater has several functions and layers. The dura mater is a sac (aka thecal sac) that envelops the arachnoid mater. It surrounds and supports the dural sinuses (also called dural venous sinuses, cerebral sinuses, or cranial sinuses) and carries blood from the brain toward the heart.
The dura mater has two layers, or lamellae: The superficial layer, which serves as the skull's inner periosteum, called the endocranium; and a deep layer, the actual dura mater.
The dura separates into two layers at dural reflections (also known as dural folds), places where the inner dural layer is reflected as sheet-like protrusions into the cranial cavity. There are two main dural reflections:
Two other dural infoldings are the cerebellar falx and the sellar diaphragm:
| This section requires expansion. (December 2009) |
The two layers of dura mater run together throughout most of the skull. Where they separate, the gap between them is called a dural venous sinus. These sinuses drain blood and cerebrospinal fluid from the brain and empty into the internal jugular vein.
Arachnoid villi, which are outgrowths of the arachnoid mater (the middle meningeal layer), extend into the venous sinuses to drain CSF. These villi act as one-way valves. Meningeal veins, which course through the dura mater, and bridging veins, which drain the underlying neural tissue and puncture the dura mater, empty into these dural sinuses. A rupture of a bridging vein causes a subdural hematoma.
| This section requires expansion. (December 2009) |
Many medical conditions involve the dura mater. A subdural hematoma occurs when there is an abnormal collection of blood between the dura and the arachnoid, usually as a result of torn bridging veins secondary to head trauma. An epidural hematoma is a collection of blood between the dura and the inner surface of the skull, and is usually due to arterial bleeding. Intradural procedures, such as removal of a brain tumour, or treatment of trigeminal neuralgia via a microvascular decompression require that an incision is made to the dura mater. To achieve a watertight repair and avoid potential post-operative complications the dura is typically closed with sutures. In the event that there is a dural deficiency, a dural substitute may be used to replace this membrane. Small gaps in the dura can be covered with a surgical sealant film.
In 2011, Scali et al., reported a connection of soft tissue from the rectus capitis posterior major to the cervical dura mater. Various clinical manifestations may be linked to this anatomical relationship such as headaches, trigeminal neuralgia and other symptoms that involved the cervical dura (Spine 2011).[5] The rectus capitis posterior minor has a similar attachment as described by Hack et al. in 1995.
The dura-muscular, dura-ligamentous connections in the upper cervical spine and occipital areas may provide anatomic and physiologic answers to the cause of the cervicogenic headache. This proposal would further explain manipulation's efficacy in the treatment of cervicogenic headache.[6]
This depends upon the area of the cranial cavity: in the anterior cranial fossa the anterior meningeal artery (branch from the ethmoidal artery) is responsible for blood supply, in the middle cranial fossa the middle meningeal artery and some accessory arteries are responsible for blood supply, the middle meningeal artery is a direct branch from the maxillary artery and enter the cranial cavity through the foramen spinosum and then divides into anterior (which runs usually in vertical direction across the pterion) and posterior (which runs posteriosuperiorly) branches, while the accessory meningeal arteries (which are branches from the maxillary artery) enter the skull through foramen ovale and supply area between the two foramens, and the in posterior cranial fossa the dura mater has numerous blood supply from different possible arteries:
A. posterior meningeal artery (from the ascending pharyngeal artery through the jugular foramen)
B. meningeal arteries (from the ascending pharyngeal artery through hypoglossal canal)
C. meningeal arteries (from occipital artery through jugular or mastoid foramen)
D. meningeal arteries (from vertebral artery through foramen magnum)
| This section requires expansion. (January 2010) |
Sensory innervation of the supratentorial dura mater is via small meningeal branches of the trigeminal nerve (V1, V2 and V3).[7] The innervation for the infratentorial dura mater are upper cervical nerves.
The American Red Cross and some other agencies accepting blood donations consider dura mater transplants, along with receipt of pituitary-derived growth hormone, a risk factor due to concerns about Creutzfeldt–Jakob disease.[8]
Dural ectasia is the enlargement of the dura and is common in connective tissue disorders, such as Marfan syndrome and Ehlers–Danlos syndrome.
Spontaneous cerebrospinal fluid leak is the fluid and pressure loss of spinal fluid due to holes in the dura mater.
Dura mater (spinal section)
Diagrammatic representation of a section across the top of the skull, showing the membranes of the brain, etc.
Diagrammatic transverse section of the medulla spinalis and its membranes.
Upper part of medulla spinalis and hind- and mid-brains; posterior aspect, exposed in situ.
Diagrammatic section of scalp.
Autopsy photo from the CDC: The white "sheet" being held by the forceps is the dura mater.
Human brain dura mater
Spinal cord. Spinal membranes and nerve roots.Deep dissection. Posterior view.
Spinal cord. Spinal membranes and nerve roots.Deep dissection. Posterior view.
Spinal cord. Spinal membranes and nerve roots.Deep dissection. Posterior view.
Spinal cord. Spinal membranes and nerve roots.Deep dissection. Posterior view.
Meninges and superficial cerebral veins.Deep dissection.Superior view.
Meninges and superficial cerebral veins.Deep dissection.Superior view.
| Wikimedia Commons has media related to Dura mater. |
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| 関連記事 | 「vein」「meningeal」 |