English Journal

Possible association between dysfunction of vitamin D binding protein (GC Globulin) and migraine attacks.

Nagata E1, Fujii N1, Hosomichi K2, Mitsunaga S3, Suzuki Y4, Mashimo Y5, Tsukamoto H6, Satoh T6, Osawa M7, Inoue I2, Hata A5, Takizawa S1.
PloS one.PLoS One.2014 Aug 22;9(8):e105319. doi: 10.1371/journal.pone.0105319. eCollection 2014.
To identify the genetic causality of migraine and acute, severe melalgia, we performed a linkage analysis and exome sequencing in a family with four affected individuals. We identified a variant (R21L) in exon 2 of the GC globulin gene, which is involved in the transportation of vitamin D metabolite
PMID 25147936

Effects of Gosha-jinki-gan (Chinese herbal medicine: Niu-Che-Sen-Qi-Wan) on hyperinsulinemia and hypertriglyceridemia in prediabetic Zucker fatty rats.

Hirotani Y1, Okumura K, Yoko U, Myotoku M.
Drug discoveries & therapeutics.Drug Discov Ther.2013 Jun;7(3):105-8.
The Chinese herbal medicine, Goshajinki-gan (GJ) (Niu-Che-Sen-Qi-Wan), has been widely used for treating patients with melalgia, lower back pain, numbness, and diabetic neuropathy. We investigated the effects of GJ on the regulation of serum insulin and triglyceride levels in obese Zucker fatty rats
PMID 23917858

NUTRITIONAL melalgia.

[No authors listed]
Nutrition reviews.Nutr Rev.1950 Nov;8(11):330-1.
PMID 14780587

Japanese Journal

Effects of Gosha-jinki-gan (Chinese herbal medicine: Niu-Che-Sen-Qi-Wan) on hyperinsulinemia and hypertriglyceridemia in pre-diabetic Zucker fatty rats

Drug Discoveries & Therapeutics 7(3), 105-108, 2013
NAID 130005054763

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