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- a nonsteroidal anti-inflammatory (trade name Meclomen) used to treat arthritis (同)meclofenamate sodium, Meclomen
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/12/31 09:08:33」(JST)
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- 1. 成人女性における原発性月経困難症の治療 treatment of primary dysmenorrhea in adult women
- 2. 非選択性非ステロイド性抗炎症剤（NSAIDs）：心血管系への有害作用 nonselective nsaids adverse cardiovascular effects
- 3. 非ステロイド性抗炎症剤（NSAIDs）中毒 nonsteroidal antiinflammatory drug nsaid poisoning
- 4. 妊娠中および授乳中のリウマチ性疾患における抗炎症剤および免疫抑制剤の使用 use of antiinflammatory and immunosuppressive drugs in rheumatic diseases during pregnancy and lactation
English Journal
- Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils.
- Domínguez-Luis M, Herrera-García A, Arce-Franco M, Armas-González E, Rodríguez-Pardo M, Lorenzo-Díaz F, Feria M, Cadenas S, Sánchez-Madrid F, Díaz-González F.SourceServicio de Reumatología, Hospital Universitario de Canarias, La Laguna, Spain.
- Biochemical pharmacology.Biochem Pharmacol.2013 Jan 15;85(2):245-56. doi: 10.1016/j.bcp.2012.10.024. Epub 2012 Nov 8.
- Non-steroidal anti-inflammatory drugs (NSAIDs) induce the shedding of L-selectin in human neutrophils through a mechanism still not well understood. In this work we studied both the functional effect of NSAIDs on the neutrophils/endothelial cells dynamic interaction, and the potential involvement of
- PMID 23142710
- Structure-activity relationship of fenamates as Slo2.1 channel activators.
- Garg P, Sanguinetti MC.SourceNora Eccles Harrison Cardiovascular Research and Training Institute, Department of Physiology, University of Utah, Salt Lake City, Utah 84112, USA.
- Molecular pharmacology.Mol Pharmacol.2012 Nov;82(5):795-802. doi: 10.1124/mol.112.079194. Epub 2012 Jul 31.
- Niflumic acid, 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid (NFA), a nonsteroidal anti-inflammatory drug that blocks cyclooxygenase (COX), was shown previously to activate [Na(+)](i)-regulated Slo2.1 channels. In this study, we report that other fenamates, including flufenamic acid
- PMID 22851714
- Development and validation of two multiresidue liquid chromatography tandem mass spectrometry methods based on a versatile extraction procedure for isolating non-steroidal anti-inflammatory drugs from bovine milk and muscle tissue.
- Gentili A, Caretti F, Bellante S, Mainero Rocca L, Curini R, Venditti A.SourceDepartment of Chemistry, Faculty of Mathematical, Physical and Natural Sciences, Sapienza University of Rome, Rome, Italy.
- Analytical and bioanalytical chemistry.Anal Bioanal Chem.2012 Sep;404(5):1375-88. doi: 10.1007/s00216-012-6231-0. Epub 2012 Jul 11.
- The main difficulties in analysing non-steroidal anti-inflammatory drugs (NSAIDs) in food and biological samples are due to the tight non-covalent interactions established with matrix proteins and the amount of occurring fatty material. The present paper describes an effective extraction procedure a
- PMID 22777033
Japanese Journal
- Nitric Oxide Buffers Renal Medullary Vasoconstriction Induced by Prostaglandins Synthesis Blockade
- NAKANISHI Kazushige,CHINEN Akira,SAITO Yoshihito,HAMADA Kaoru,HARA Noriko,NAGAI Yohko
- Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 24(6), 699-704, 2001-11-01
- … Infusion of meclofenamate, a nonisozyme-specific cyclooxygenase (COX) inhibitor, at 5μg/kg/min over 4 consecutive days (n=12 rats) elicited a transitory increase (p<0.05) in mean arterial pressure (MAP) and a transitory decrease (p<0.05) in MBF and sodium excretion without altering CBF. …
- NAID 10009565678
- Dock4.0を用いた非ステロイド性抗炎症剤のCOX1およびCOX2に対する結合モードに関する研究
- 赤穂 栄一,藤川 智香子,Runion Howell I. [他],HILL Craig R,中野 英彦
- The Journal of chemical software 5(4), 147-162, 1999-12-15
- … COX１の阻害モードに関しては1種類が類似、他の1種類が類似せず、3番目は中間であったnabumetone, meclofenamate, niflumic acid, indomethacin, sulindac, および flurbiprofenのごときNSAIDがCOX2に結合する場合、1から3種類（延べ少なくとも１２種類）の水素結合が存在することがわかった。 …
- NAID 10004709279
- 持久的運動トレーニングラットにおける低酸素性肺血管収縮に一酸化窒素合成酵素阻害剤が与える影響
- 樫村 修生,酒井 秋男
- 体力科学 47(5), 573-579, 1998
- … This study determined whether nitric oxide (NO) plays a role in inhibition of the HPV after endurance exercise training in isolated rat lung perfused with physiological saline solution containing meclofenamate. …
- NAID 130001836218
Related Links
- Learn about the prescription medication Meclofenamate (Meclofenamate), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. ... What are the precautions when taking meclofenamate ...
- Meclofenamate is also used to treat ankylosing spondylitis (arthritis that mainly affects the spine), gouty arthritis (joint pain caused by a build-up of certain substances in the joints), and psoriatic arthritis (arthritis that ...
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★リンクテーブル★
| リンク元 | 「メクロフェナム酸」 |
「メクロフェナム酸」
-meclofenamate