luciferase gene

WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
informal term for information; "give me the gen on your new line of computers"

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Molecular characterization and function of the Prohibitin2 gene in Litopenaeus vannamei responses to Vibrio alginolyticus.

Gu MM1, Kong JR1, Di-Huang1, Peng T1, Xie CY1, Yang KY2, Liu Y1, Wang WN3.
Developmental and comparative immunology.Dev Comp Immunol.2017 Feb;67:177-188. doi: 10.1016/j.dci.2016.10.004. Epub 2016 Oct 15.
Prohibitin2 (PHB2), a potential tumor suppressor protein, plays important roles in inhibition of cell cycle progression, transcriptional regulation, apoptosis and the mitochondrial respiratory chain. To explore its potential roles in crustaceans' immune responses we have identified and characterized
PMID 27756688

MicroRNA-590-5p Stabilizes Runx2 by Targeting Smad7 During Osteoblast Differentiation.

Vishal M1, Vimalraj S1, Ajeetha R1, Gokulnath M1, Keerthana R1, He Z2, Partridge NC2, Selvamurugan N3.
Journal of cellular physiology.J Cell Physiol.2017 Feb;232(2):371-380. doi: 10.1002/jcp.25434. Epub 2016 Jun 15.
Mesenchymal stem cells (MSCs) are multipotent cells and their differentiation into the osteoblastic lineage is strictly controlled by several regulators, including microRNAs (miRNAs). Runx2 is a bone transcription factor required for osteoblast differentiation. Here, we used in silico analysis to id
PMID 27192628

Functional polymorphisms in PD-L1 gene are associated with the prognosis of patients with early stage non-small cell lung cancer.

Lee SY1, Jung DK2, Choi JE3, Jin CC2, Hong MJ3, Do SK2, Kang HG3, Lee WK4, Seok Y5, Lee EB5, Jeong JY6, Shin KM7, Yoo SS1, Lee J8, Cha SI8, Kim CH8, Park JY9.
Gene.Gene.2017 Jan 30;599:28-35. doi: 10.1016/j.gene.2016.11.007. Epub 2016 Nov 10.
INTRODUCTION: This study was conducted to investigate whether polymorphisms of genes involved in immune checkpoints can predict the prognosis of patients with early stage non-small cell lung cancer (NSCLC) after surgical resection.MATERIALS AND METHODS: Twelve single nucleotide polymorphisms (SNPs)
PMID 27838455

Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation

Otani Yuki,Kawakami Shigeru,Mukai Hidefumi,Fuchigami Yuki,Yamashita Fumiyoshi,Hashida Mitsuru
Journal of Drug Targeting 23(5), 427-435, 2015-06-01
… Background: Achieving long-term gene expression in kidney will be beneficial for gene therapy of renal and congenital diseases, genetic studies constructing animal disease models, and the functional analysis of disease-related genes. … Purpose: The purpose of this study was to develop an in vivo long-term gene expression system in murine kidney using φC31 integrase. … Methods: Gene expression in cultured RENCA, TCMK-1, and HEK293 cells was assessed. …
NAID 120005621902

microRNA-340-5p Functions Downstream of Cardiotrophin-1 to Regulate Cardiac Eccentric Hypertrophy and Heart Failure via Target Gene Dystrophin

Zhou Jian,Gao Jie,Zhang Xiaoya,Liu Yan,Gu Song,Zhang Xitao,An Xiangguang,Yan Jun,Xin Yue,Su Pixiong
International Heart Journal 56(4), 454-458, 2015
… Recently, we observed upregulation of microRNA-340-5p (miR-340) in failing human hearts because of dilated cardiomyopathy, but the functional consequence of miR-340 remains to be clarified.We transfected neonatal cardiomyocytes with miR-340 and found fetal gene expression including Nppa, Nppb and Myh7. … Knockdown of miR-340 using antagomir attenuated fetal gene expression and hypertrophy formation, which means miR-340 could convey the hypertrophic signal of CT-1. …
NAID 130005087581