listeriolysin

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1. リステリア菌感染の疫学および病因 epidemiology and pathogenesis of listeria monocytogenes infection
2. リステリア菌感染の臨床症状および診断 clinical manifestations and diagnosis of listeria monocytogenes infection
3. クロストリジウム性筋肉壊死 clostridial myonecrosis

PLGA-Listeriolysin O microspheres: Opening the gate for cytosolic delivery of cancer antigens.

Gilert A1, Baruch L1, Bronshtein T1, Machluf M2.
Biomedical microdevices.Biomed Microdevices.2016 Apr;18(2):23. doi: 10.1007/s10544-016-0050-6.
Strategies for cancer protein vaccination largely aim to activate the cellular arm of the immune system against cancer cells. This approach, however, is limited since protein vaccines mostly activate the system's humoral arm instead. One way to overcome this problem is to enhance the cross-presentat
PMID 26888439

Eugenol in combination with lactic acid bacteria attenuate Listeria monocytogenes virulence in vitro and in invertebrate model, Galleria mellonella.

Upadhyay A1, Upadhyaya I2, Mooyottu S3, Venkitanarayanan K4.
Journal of medical microbiology.J Med Microbiol.2016 Mar 22. doi: 10.1099/jmm.0.000251. [Epub ahead of print]
Listeria monocytogenes is a human enteric pathogen that causes severe foodborne illness in high-risk populations. Crossing the intestinal barrier is the first critical step for L. monocytogenes infection. Therefore, reducing L. monocytogenes colonization and invasion of intestinal epithelium and pro
PMID 27002648

Liposomal Coencapsulation of Doxorubicin with Listeriolysin O Increases Potency via Subcellular Targeting.

Walls ZF1, Gong H1, Wilson RJ1.
Molecular pharmaceutics.Mol Pharm.2016 Mar 7;13(3):1185-90. doi: 10.1021/acs.molpharmaceut.5b00674. Epub 2016 Jan 25.
Liposomal doxorubicin is a clinically important drug formulation indicated for the treatment of several different forms of cancer. For doxorubicin to exert a therapeutic effect, it must gain access to the nucleus. However, a large proportion of the liposomal doxorubicin dose fails to work because it
PMID 26751497