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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/27 10:48:28」(JST)

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Target-controlled infusion and population pharmacokinetics of landiolol hydrochloride in gynecologic patients.

Kunisawa T1, Yamagishi A, Suno M, Nakade S, Higashi R, Kurosawa A, Sugawara A, Matsubara K, Iwasaki H.
Journal of anesthesia.J Anesth.2015 Apr;29(2):198-205. doi: 10.1007/s00540-014-1908-5. Epub 2014 Sep 4.
PURPOSE: We previously determined the pharmacokinetic (PK) parameters of landiolol in healthy male volunteers. In this study, we evaluated the usefulness of target-controlled infusion (TCI) of landiolol hydrochloride and determined PK parameters of landiolol in gynecologic patients.METHODS: Nine pat
PMID 25186494

Efficacy of landiolol for the treatment of junctional ectopic tachycardia resulting from sepsis.

Oka H1, Sugimoto M1, Azuma H1.
Cardiology in the young.Cardiol Young.2015 Mar 18:1-5. [Epub ahead of print]
Junctional ectopic tachycardia, after surgery for CHD, is a serious arrhythmia that can cause increased morbidity and mortality. We report a case of junctional ectopic tachycardia, preceded by sepsis, in a 4-year-old girl, 31 months after open-heart surgery. She was successfully treated using low-do
PMID 25785611

Landiolol in the treatment of the intraoperative supraventricular tachycardia: a multicenter, randomized, double-blind, placebo-controlled study.

Xiao J1, He P1, Zou Q1, Zhao Y1, Xue Z2, Deng X3, Li S4, Guo Q5, Tao G6, Yang T7, Lang Z8, He J9, Wang X10.
Journal of clinical anesthesia.J Clin Anesth.2015 Mar;27(2):120-8. doi: 10.1016/j.jclinane.2014.07.003. Epub 2014 Nov 28.
BACKGROUND: Supraventricular tachycardia during the induction of anesthesia may carry a higher risk.STUDY OBJECTIVE: The aim of this study was to evaluate efficacy and safety of intravenous landiolol in Chinese patients with intraoperative supraventricular tachycardia during anesthesia.DESIGN: A ran
PMID 25434501

Target-controlled infusion and population pharmacokinetics of landiolol hydrochloride in patients with peripheral arterial disease.

リンク元	「ランジオロール」
拡張検索	「landiolol hydrochloride」

Landiolol
Systematic (IUPAC) name
	[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ (Prescription only);
Routes of; administration	IV
Identifiers
CAS Number	133242-30-5
ATC code	None
PubChem	CID: 114905
ChemSpider	102855
UNII	62NWQ924LH
Chemical data
Formula	C25H39N3O8
Molecular mass	509.59 g/mol
	SMILES CC1(OCC(O1)COC(=O)CCC2=CC=C(C=C2)OCC(CNCCNC(=O)N3CCOCC3)O)C ;
	InChI InChI=1S/C25H39N3O8/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28/h3-4,6-7,20,22,26,29H,5,8-18H2,1-2H3,(H,27,31)/t20-,22+/m0/s1 ; Key:WMDSZGFJQKSLLH-RBBKRZOGSA-N ;
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