ランジオロール
- 関
- landiolol hydrochloride
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/11/27 10:48:28」(JST)
[Wiki en表示]
Landiolol
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Systematic (IUPAC) name |
[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate
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Clinical data |
AHFS/Drugs.com |
International Drug Names |
Legal status |
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Routes of
administration |
IV |
Identifiers |
CAS Number |
133242-30-5 Y |
ATC code |
None |
PubChem |
CID: 114905 |
ChemSpider |
102855 N |
UNII |
62NWQ924LH Y |
Chemical data |
Formula |
C25H39N3O8 |
Molecular mass |
509.59 g/mol |
SMILES
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CC1(OCC(O1)COC(=O)CCC2=CC=C(C=C2)OCC(CNCCNC(=O)N3CCOCC3)O)C
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InChI
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InChI=1S/C25H39N3O8/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28/h3-4,6-7,20,22,26,29H,5,8-18H2,1-2H3,(H,27,31)/t20-,22+/m0/s1 N
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Key:WMDSZGFJQKSLLH-RBBKRZOGSA-N N
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N (what is this?) (verify) |
Landiolol (INN) is a drug which acts as a highly cardioselective, ultra short-acting beta blocker. It is used as an anti-arrhythmic agent.
References
- Yoshiya I (December 1998). "[Landiolol hydrochloride, a new sympathetic beta blocker]". Masui (in Japanese). 47 Suppl: S126–32. PMID 9921175.
- Ogata J, Okamoto T, Minami K (2003). "Landiolol for the treatment of tachyarrhythmia associated with atrial fibrillation". Can J Anaesth 50 (7): 753. doi:10.1007/BF03018726. PMID 12944459.
UpToDate Contents
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English Journal
- Target-controlled infusion and population pharmacokinetics of landiolol hydrochloride in gynecologic patients.
- Kunisawa T1, Yamagishi A, Suno M, Nakade S, Higashi R, Kurosawa A, Sugawara A, Matsubara K, Iwasaki H.
- Journal of anesthesia.J Anesth.2015 Apr;29(2):198-205. doi: 10.1007/s00540-014-1908-5. Epub 2014 Sep 4.
- PURPOSE: We previously determined the pharmacokinetic (PK) parameters of landiolol in healthy male volunteers. In this study, we evaluated the usefulness of target-controlled infusion (TCI) of landiolol hydrochloride and determined PK parameters of landiolol in gynecologic patients.METHODS: Nine pat
- PMID 25186494
- Efficacy of landiolol for the treatment of junctional ectopic tachycardia resulting from sepsis.
- Oka H1, Sugimoto M1, Azuma H1.
- Cardiology in the young.Cardiol Young.2015 Mar 18:1-5. [Epub ahead of print]
- Junctional ectopic tachycardia, after surgery for CHD, is a serious arrhythmia that can cause increased morbidity and mortality. We report a case of junctional ectopic tachycardia, preceded by sepsis, in a 4-year-old girl, 31 months after open-heart surgery. She was successfully treated using low-do
- PMID 25785611
- Landiolol in the treatment of the intraoperative supraventricular tachycardia: a multicenter, randomized, double-blind, placebo-controlled study.
- Xiao J1, He P1, Zou Q1, Zhao Y1, Xue Z2, Deng X3, Li S4, Guo Q5, Tao G6, Yang T7, Lang Z8, He J9, Wang X10.
- Journal of clinical anesthesia.J Clin Anesth.2015 Mar;27(2):120-8. doi: 10.1016/j.jclinane.2014.07.003. Epub 2014 Nov 28.
- BACKGROUND: Supraventricular tachycardia during the induction of anesthesia may carry a higher risk.STUDY OBJECTIVE: The aim of this study was to evaluate efficacy and safety of intravenous landiolol in Chinese patients with intraoperative supraventricular tachycardia during anesthesia.DESIGN: A ran
- PMID 25434501
Japanese Journal
- 房室伝導比2:1の心房粗動持続により頻脈誘発性心筋症をきたし,うっ血性心不全を発症した1例(症例検討)
- デクスメデトミジンとランジオロールを用いて鎮静を行った脊髄くも膜下麻酔の1症例
- Target-controlled infusion and population pharmacokinetics of landiolol hydrochloride in patients with peripheral arterial disease.
Related Links
- Landiolol (INN) is a drug which acts as a highly cardioselective, ultra short-acting beta blocker. It is used as an anti-arrhythmic agent. References [edit] Yoshiya I (December 1998). "[Landiolol hydrochloride, a new sympathetic beta ...
- Anesthesia 21 Century Vol.10 No.2-31 2008 (1881) 31 Short-Acting Type Beta Blocker:Landiolol and Esmolol 参考文献 1)London MJ:Quo Vadis, Perioperative beta blockade? Are you“POISE'd”on the brink? Anesth Analg ...
Related Pictures
![Let Me Buy](https://1mg.info/0/8/z/1153.jpg)
![Landiolol.png](https://1mg.info/0/8/z/1154.jpg)
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![Landiolol](https://1mg.info/0/8/z/1157.jpg)
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