WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
a small amount of liquor added to a food or beverage
resinlike substance secreted by certain lac insects; used in e.g. varnishes and sealing wax
the syllable naming the sixth (submediant) note of a major or minor scale in solmization (同)lah
informal term for information; "give me the gen on your new line of computers"

PrepTutorEJDIC

遺伝子
〈U〉ひもで縛ること;レース飾りをつけること / 〈U〉(各種の用途の)ひも,レース,金(銀)モール / 〈U〉〈C〉《話》むち打ち / 〈U〉酒を加えること
ラック(ワニス・赤色染料の原料)
ラ(全音階の第6音)

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1. 遺伝子治療、ゲノム編集、遺伝子発現抑制の概要overview of gene therapy gene editing and gene silencing [show details]
… Insertion of genes that inhibit immune or inflammatory responses (eg, genes from the adenoviral early region 3 [E3] that is responsible for downregulating host responses) . Deletion of viral genes that may …
2. 原発性免疫不全症に対する遺伝子治療gene therapy for primary immunodeficiency [show details]
…of immunodeficiencies are discussed separately. Gene therapy has the potential to cure genetically based diseases. In gene addition therapy, the gene copy must be introduced into a sufficient number of …
3. 遺伝学およびゲノミクスのためのツール：遺伝子発現プロファイリングtools for genetics and genomics gene expression profiling [show details]
… of the expression of thousands of genes simultaneously. In general, the greater the amount of mRNA from a particular gene (ie, the higher the expression of that gene), the more fluorescently-labeled material …
4. 肥大型心筋症：遺伝子変異および臨床遺伝子検査hypertrophic cardiomyopathy gene mutations and clinical genetic testing [show details]
… 2019, up to 11 causative genes with over 1500 mutations in genes encoding the thick or thin myofilament proteins of the sarcomere have been reported . In an analysis of 33 genes frequently included in HCM …
5. ネフロン癆の遺伝学および病因genetics and pathogenesis of nephronophthisis [show details]
… Patients with NPHP have gene mutations that encode components of the ciliary apparatus . Although mutations in NPHP1 gene account for 20 percent of cases, at least 20 different genes have been associated …

English Journal

What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems.

Bhogale PM1, Sorg RA2, Veening JW3, Berg J4.
Nucleic acids research.Nucleic Acids Res.2015 Feb 1;42(18):11321-8. doi: 10.1093/nar/gku839. Epub 2014 Sep 22.
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate selection in viral infection, cell-cycle control and d
PMID 25245949

A Novel, Broad-Range, CTXΦ-Derived Stable Integrative Expression Vector for Functional Studies.

Das B1, Kumari R2, Pant A2, Sen Gupta S2, Saxena S2, Mehta O2, Nair GB2.
Journal of bacteriology.J Bacteriol.2014 Dec 1;196(23):4071-80. doi: 10.1128/JB.01966-14. Epub 2014 Sep 15.
CTXΦ, a filamentous vibriophage encoding cholera toxin, uses a unique strategy for its lysogeny. The single-stranded phage genome forms intramolecular base-pairing interactions between two inversely oriented XerC and XerD binding sites (XBS) and generates a functional phage attachment site, attP(+)
PMID 25225263

Assembling Flagella in Salmonella Mutant Strains Producing a Type III Export Apparatus without FliO.

Barker CS1, Meshcheryakova IV2, Inoue T2, Samatey FA1.
Journal of bacteriology.J Bacteriol.2014 Dec 1;196(23):4001-11. doi: 10.1128/JB.02184-14. Epub 2014 Sep 8.
The type III export apparatus of the Salmonella flagellum consists of six transmembrane proteins (FlhA, FlhB, FliO, FliP, FliQ, and FliR) and three soluble proteins (FliH, FliI, and FliJ). Deletion of the fliO gene creates a mutant strain that is poorly motile; however, suppressor mutations in the f
PMID 25201947

Japanese Journal

Exploration of natural nod gene inducers for Mesorhizobium loti in seed and root exudates of Lotus corniculatus

Kojima Katsuhiro,Yokoyama Tadashi,Ohkama-Ohtsu Naoko,Saengkerdsub Suwat,Itakura Manabu,Mitsui Hisayuki,Minamisawa Kiwamu,Arima Yasuhiro
土と微生物 66(1), 12-21, 2012-04-01
… Tetronic acid is a candidate for an inducer of nodulation (nod) gene expression in Mesorhizobium loti. … This suggests that Lotus plants may produce other genuine nod gene inducers that differ from tetronic acid. … loti cells harboring a nodA-lacZ fusion were enclosed in dialysis tubing and immersed in L. … loti cells, indicating that nod gene inducers were present in the seed and root exudates. …
NAID 110009437362

Preclinical Safety and Efficacy of in Situ REIC/Dkk-3 Gene Therapy for Prostate Cancer

Kawauchi Keiichiro,Watanabe Masami,Kaku Haruki,Huang Peng,Sasaki Kasumi,Sakaguchi Masakiyo,Ochiai Kazuhiko,Huh Nam-ho,Nasu Yasutomo,Kumon Hiromi
Acta Medica Okayama 66(1), 7-16, 2012-02-00
… The preclinical safety and therapeutic efficacy of adenoviral vectors that express the REIC/Dkk-3 tumor suppressor gene (Ad-REIC) was examined for use in prostate cancer gene therapy. … Both experiments indicated that there was no significant difference in the examined parameters between the Ad-REIC-treated group and the control (PBS- or Ad-LacZ-treated) group. …
NAID 120003850603