キニナーゼ
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Japanese Journal
- A Missing Link Between a High Salt Intake and Blood Pressure Increase
- KATORI Makoto,MAJIMA Masataka
- Journal of pharmacological sciences 100(5), 370-390, 2006-05-15
- … Furthermore, pharmaceutical development of renal kallikrein releasers, such as KATP channel blockers, and renal kininase inhibitors, such as ebelactone B, may lead to the development of novel antihypertensive drugs. …
- NAID 10018238332
- Role of Aminopeptidases in the Blood Pressure Regulation(Aminopeptidases in Health and Disease)
- MITSUI Takashi,NOMURA Seiji,ITAKURA Atsuo,MIZUTANI Shigehiko
- Biological & pharmaceutical bulletin 27(6), 768-771, 2004-06-01
- … This review describes the roles of aminopeptidase A, placental leucine aminopeptidase and kininase I, which are enzymes responsible for hydrolyzing angiotensin II (Angll), vasopressin (AVP) and bradykinin (BK), respectively, in BP regulation. …
- NAID 110003608852
- Identification of Kallidin Degrading Enzymes in the Isolated Perfused Rat Heart
- WOLFRUM Sebastian,DENDORFER Andreas,DOMINIAK Peter
- The Japanese journal of pharmacology 79(1), 117-120, 1999-01
- … By inhibiting angiotensin-converting enzyme (ACE), aminopeptidase M (APM) and neutral endopeptidase (NEP) with ramiprilat (0.25 μM), amastatin (40 μM) and phosphoramidon (1 μM), respectively, relative kininase activities were obtained. …
- NAID 10008194342
Related Links
- 1-3) Angioedema due to ACE inhibitors appears to be linked to the decreased degradation of bradykinin because ACE, also known as kininase II, not only activates ... Angiotensin II [formed from angiotensin I in a reaction catalyzed ...
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アンジオテンシン変換酵素, CD143